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E9Q1R7 (E9Q1R7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:Tiam1 Ensembl ENSMUSP00000126020 MGI 103306
OrganismMus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000126020
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length622 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains DH (DBL-homology) domain. SAAS SAAS001331

Contains PH domain. SAAS SAAS000219

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000126020

Sequences

Sequence LengthMass (Da)Tools
E9Q1R7 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 20549BC068A55E80

FASTA62270,648
        10         20         30         40         50         60 
MSSLWKIKRK PRVESDRAGD SLYRTLHLST EQVAAFCRSL HEMSPSDSSP SPQDATSPQL 

        70         80         90        100        110        120 
ATTRQLSDAD KLRKVICELL ETERTYVKDL NCLMERYLKP LQKETFLTQD ELDVLFGNLT 

       130        140        150        160        170        180 
EMVEFQVEFL KTLEDGVRLV PDLEKLEKVD QFKKVLFSLG GSFLYYADRF KLYSAFCASH 

       190        200        210        220        230        240 
TKVPKVLVKA KTDTAFKAFL DAQNPRQQHS STLESYLIKP IQRVLKYPLL LRELFALTDA 

       250        260        270        280        290        300 
ESEEHYHLDV AIKTMNKVAS HINEMQKIHE EFGAVFDQLI AEQTGEKKEV ADLSMGDLLL 

       310        320        330        340        350        360 
HTSVIWLNPP ASLGKWKKEP ELAAFVFKTA VVLVYKDGSK QKKKLVGSHR LSIYEEWDPF 

       370        380        390        400        410        420 
RFRHMIPTEA LQVRALPSAD AEANAVCEIV HVKSESEGRP ERVFHLCCSS PESRKDFLKS 

       430        440        450        460        470        480 
VHSILRDKHR RQLLKTESLP SAQQYVPFGG KRLCALKGAR PAMSRAVSAP SKSLGRRRRR 

       490        500        510        520        530        540 
LARNRFTIDS DAISASSPEK EPQQPAGGGD TDRWVEEQFD LAQYEEQDDI KETDILSDDD 

       550        560        570        580        590        600 
EFCESLKGAS VDRDLQEQLQ AASISQRARG RRTLDSHASR MTQLKKQAAL SGINGGLESA 

       610        620 
SEEVIWVRRE DFAPSRKLNT EI 

« Hide

References

« Hide 'large scale' references
[1]"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., Zha X.M., Polakiewicz R.D., Comb M.J.
Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[2]"Quantitative time-resolved phosphoproteomic analysis of mast cell signaling."
Cao L., Yu K., Banh C., Nguyen V., Ritz A., Raphael B.J., Kawakami Y., Kawakami T., Salomon A.R.
J. Immunol. 179:5864-5876(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[3]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000126020.
[4]Ensembl
Submitted (MAY-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000126020.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC087840 Genomic DNA. No translation available.
AC102908 Genomic DNA. No translation available.
AC122218 Genomic DNA. No translation available.
RefSeqNP_001139359.1. NM_001145887.1.
UniGeneMm.310902.

3D structure databases

ProteinModelPortalE9Q1R7.
SMRE9Q1R7. Positions 65-432.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000164263; ENSMUSP00000126020; ENSMUSG00000002489.
GeneID21844.
KEGGmmu:21844.
UCSCuc007zvs.2. mouse.

Organism-specific databases

CTD7074.
MGIMGI:103306. Tiam1.

Phylogenomic databases

GeneTreeENSGT00740000114955.
KOK05731.
TreeFamTF319686.

Gene expression databases

ArrayExpressE9Q1R7.
BgeeE9Q1R7.

Family and domain databases

Gene3D1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProIPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR011993. PH_like_dom.
IPR001849. Pleckstrin_homology.
[Graphical view]
PfamPF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMSSF48065. SSF48065. 1 hit.
PROSITEPS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio301314.
SOURCESearch...

Entry information

Entry nameE9Q1R7_MOUSE
AccessionPrimary (citable) accession number: E9Q1R7
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 14, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)