ID   E9Q1I6_MOUSE            Unreviewed;       165 AA.
AC   E9Q1I6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   RecName: Full=Protein Mpv17 {ECO:0000256|ARBA:ARBA00040811};
GN   Name=Mpv17 {ECO:0000313|Ensembl:ENSMUSP00000143843.2,
GN   ECO:0000313|MGI:MGI:97138};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000143843.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000143843.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000143843.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0007829|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000143843.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000143843.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC       {ECO:0000256|ARBA:ARBA00006824, ECO:0000256|RuleBase:RU363053}.
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DR   RefSeq; NP_001281251.1; NM_001294322.1.
DR   AlphaFoldDB; E9Q1I6; -.
DR   jPOST; E9Q1I6; -.
DR   MaxQB; E9Q1I6; -.
DR   ProteomicsDB; 327079; -.
DR   Antibodypedia; 28381; 195 antibodies from 28 providers.
DR   DNASU; 17527; -.
DR   Ensembl; ENSMUST00000200744.4; ENSMUSP00000143843.2; ENSMUSG00000107283.4.
DR   GeneID; 17527; -.
DR   UCSC; uc056zzc.1; mouse.
DR   AGR; MGI:97138; -.
DR   CTD; 4358; -.
DR   MGI; MGI:97138; Mpv17.
DR   VEuPathDB; HostDB:ENSMUSG00000107283; -.
DR   GeneTree; ENSGT00940000160891; -.
DR   OrthoDB; 314578at2759; -.
DR   BioGRID-ORCS; 17527; 1 hit in 45 CRISPR screens.
DR   ChiTaRS; Mpv17; mouse.
DR   Proteomes; UP000000589; Chromosome 5.
DR   Bgee; ENSMUSG00000107283; Expressed in right kidney and 256 other cell types or tissues.
DR   ExpressionAtlas; E9Q1I6; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007248; Mpv17_PMP22.
DR   PANTHER; PTHR11266; PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17; 1.
DR   PANTHER; PTHR11266:SF17; PROTEIN MPV17; 1.
DR   Pfam; PF04117; Mpv17_PMP22; 1.
PE   1: Evidence at protein level;
KW   Membrane {ECO:0000256|RuleBase:RU363053};
KW   Proteomics identification {ECO:0007829|EPD:E9Q1I6,
KW   ECO:0007829|MaxQB:E9Q1I6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Transmembrane {ECO:0000256|RuleBase:RU363053};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363053}.
FT   TRANSMEM        51..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363053"
FT   TRANSMEM        95..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363053"
FT   TRANSMEM        135..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363053"
SQ   SEQUENCE   165 AA;  18357 MW;  C78AF99B529F374D CRC64;
     MALWRAYQRA LAAHPWKVQV LTAGSLMGVG DMISQQLVER RGLQQHQAGR TLTMVSLGCG
     FVGPVVGGWY KVLDHLIPGT TKVHALKKML LDQGGFAPCF LGCFLPLVGI LNGMSAQDNW
     AKLKRLWPAV QLANFYLVPL HYRLAVVQCV AIVWNSYLSW KAHQF
//