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E9Q1G1

- E9Q1G1_MOUSE

UniProt

E9Q1G1 - E9Q1G1_MOUSE

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Protein
Submitted name: Alpha-aminoadipic semialdehyde dehydrogenase
Gene
Aldh7a1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. oxidoreductase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Alpha-aminoadipic semialdehyde dehydrogenaseImported
    Gene namesi
    Name:Aldh7a1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 18

    Organism-specific databases

    MGIiMGI:108186. Aldh7a1.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: MGI
    Complete GO annotation...

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q1G1.
    BgeeiE9Q1G1.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q1G1.
    SMRiE9Q1G1. Positions 21-121.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00720000108597.

    Family and domain databases

    Gene3Di3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    E9Q1G1-1 [UniParc]FASTAAdd to Basket

    « Hide

    VQSVKTSKLS GPWSRPAAHM STLLIHHPQY AWLQDLGLRE DNEGVYNGSW    50
    GGRGEASLKD YEETIGKAKK AWNIWADIPA PKRGEIVRKI GDAFREKIQL 100
    LGRLVSLEMG KILVEGIGEV Q 121
    Length:121
    Mass (Da):13,478
    Last modified:November 16, 2011 - v2
    Checksum:iDBF98985B597A3FA
    GO

    Non-terminal residue

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei121 – 1211Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC162035 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000171844; ENSMUSP00000127652; ENSMUSG00000053644.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC162035 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9Q1G1.
    SMRi E9Q1G1. Positions 21-121.
    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000171844 ; ENSMUSP00000127652 ; ENSMUSG00000053644 .

    Organism-specific databases

    MGIi MGI:108186. Aldh7a1.

    Phylogenomic databases

    GeneTreei ENSGT00720000108597.

    Miscellaneous databases

    NextBioi 35554717.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q1G1.
    Bgeei E9Q1G1.

    Family and domain databases

    Gene3Di 3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    3. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J., Newman J.C., Held J.M., Cusack M.P., Sorensen D.J., Li B., Schilling B., Mooney S.D., Kahn C.R., Verdin E., Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A. 110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiE9Q1G1_MOUSE
    AccessioniPrimary (citable) accession number: E9Q1G1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: November 16, 2011
    Last modified: May 14, 2014
    This is version 21 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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