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Protein
Submitted name:

Semaphorin-3C

Gene

Sema3c

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • chemorepellent activity Source: GO_Central
  • neuropilin binding Source: GO_Central
  • semaphorin receptor binding Source: MGI

GO - Biological processi

  • blood vessel remodeling Source: MGI
  • dichotomous subdivision of terminal units involved in salivary gland branching Source: MGI
  • heart development Source: MGI
  • negative chemotaxis Source: GO_Central
  • negative regulation of axon extension involved in axon guidance Source: GO_Central
  • neural crest cell migration Source: MGI
  • positive regulation of cell migration Source: GO_Central
  • post-embryonic development Source: MGI
  • semaphorin-plexin signaling pathway Source: GO_Central
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Semaphorin-3CImported
Gene namesi
Name:Sema3cImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:107557. Sema3c.

Subcellular locationi

GO - Cellular componenti

  • extracellular exosome Source: MGI
  • extracellular space Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 226205Sequence analysisPRO_5003243054Add
BLAST

Proteomic databases

PaxDbiE9Q0Z0.

Expressioni

Gene expression databases

BgeeiE9Q0Z0.
ExpressionAtlasiE9Q0Z0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030568.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini28 – 226199SemaInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410XQZC. LUCA.
KOG3611. Eukaryota.
GeneTreeiENSGT00760000118854.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR001627. Semap_dom.
IPR027231. Semaphorin.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11036. PTHR11036. 1 hit.
PfamiPF01403. Sema. 1 hit.
[Graphical view]
SUPFAMiSSF101912. SSF101912. 1 hit.
PROSITEiPS51004. SEMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9Q0Z0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFRAICVLV GVFICSICVR GSSQPQARVY LTFDELRETK TSEYFSLSHQ
60 70 80 90 100
QLDYRILLMD EDQDRIYVGS KDHILSLNIN NISQEPLSVF WPASTIKVEE
110 120 130 140 150
CKMAGKDPTH GCGNFVRVIQ TFNRTHLYVC GSGAFSPVCT YLNRGRRSEV
160 170 180 190 200
FMIDSKCESG KGRCSFNPNV NTVSVMINEE LFSGMYIDFM GTDAAIFRSL
210 220
TKRNAVRTDQ HNSKWLSEPM FVDAHV
Length:226
Mass (Da):25,641
Last modified:April 5, 2011 - v1
Checksum:iBEC1C7C05FC032E0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei226 – 2261Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122936 Genomic DNA. No translation available.
AC161507 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000169603; ENSMUSP00000132330; ENSMUSG00000028780.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122936 Genomic DNA. No translation available.
AC161507 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030568.

Proteomic databases

PaxDbiE9Q0Z0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000169603; ENSMUSP00000132330; ENSMUSG00000028780.

Organism-specific databases

MGIiMGI:107557. Sema3c.

Phylogenomic databases

eggNOGiENOG410XQZC. LUCA.
KOG3611. Eukaryota.
GeneTreeiENSGT00760000118854.

Miscellaneous databases

NextBioi35554654.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q0Z0.
ExpressionAtlasiE9Q0Z0. baseline and differential.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR001627. Semap_dom.
IPR027231. Semaphorin.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PANTHERiPTHR11036. PTHR11036. 1 hit.
PfamiPF01403. Sema. 1 hit.
[Graphical view]
SUPFAMiSSF101912. SSF101912. 1 hit.
PROSITEiPS51004. SEMA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q0Z0_MOUSE
AccessioniPrimary (citable) accession number: E9Q0Z0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: December 9, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.