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E9PZW0

- E9PZW0_MOUSE

UniProt

E9PZW0 - E9PZW0_MOUSE

Protein
Submitted name:

Desmoplakin

Gene

Dsp

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. adherens junction organization Source: MGI
    2. desmosome organization Source: MGI
    3. intermediate filament cytoskeleton organization Source: MGI
    4. single organismal cell-cell adhesion Source: MGI
    5. skin development Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    DesmoplakinImported
    Gene namesi
    Name:DspImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 13

    Organism-specific databases

    MGIiMGI:109611. Dsp.

    Subcellular locationi

    GO - Cellular componenti

    1. basolateral plasma membrane Source: MGI
    2. cell-cell junction Source: MGI
    3. cytoskeleton Source: InterPro
    4. desmosome Source: MGI
    5. intercalated disc Source: MGI
    6. membrane Source: MGI
    7. mitochondrion Source: MGI

    PTM / Processingi

    Proteomic databases

    PRIDEiE9PZW0.

    Expressioni

    Gene expression databases

    ArrayExpressiE9PZW0.
    BgeeiE9PZW0.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PZW0.
    SMRiE9PZW0. Positions 190-639, 1622-1861, 2026-2221.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00720000108730.
    KOiK10381.
    OrthoDBiEOG7TQTZV.

    Family and domain databases

    Gene3Di3.90.1290.10. 5 hits.
    InterProiIPR028462. Desmoplakin.
    IPR001101. Plectin_repeat.
    IPR018159. Spectrin/alpha-actinin.
    [Graphical view]
    PANTHERiPTHR11915:SF234. PTHR11915:SF234. 1 hit.
    PfamiPF00681. Plectin. 8 hits.
    [Graphical view]
    SMARTiSM00250. PLEC. 18 hits.
    SM00150. SPEC. 2 hits.
    [Graphical view]
    SUPFAMiSSF75399. SSF75399. 5 hits.

    Sequencei

    Sequence statusi: Complete.

    E9PZW0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSCNGGSHPR INTLGRMTRA ESGPDLRYEM TYSGGGGGGG GGGGGGTSRT     50
    FYSHSRRCTV NDQNSDGYCQ TGTMSRHQNQ NTIQEMLQNC SDCLMRAELI 100
    AQPELKFGEG MQLAWNRELD EYFTQANDQM EIIDGLIREM RQMGQPCDAY 150
    QKRLLQLQEQ MRALYKAISV PRVRRASSKG AGGYTCQSGS GWDEFTKRLT 200
    GECLGWMRQQ REEMDLMAWG VDAGSVEQHI NSHRSIHNTI GDYRWQLDKI 250
    KADLREKSAI YQLEEEYENL LKASFERMDH LRQLQNIIQA TSREIMWIND 300
    CEEEELLYDW SDKNTNIAQK QEAFSIRMSQ LEVKEKELNK LKQESDQLVL 350
    NQHPASDKIE AYMDTLQTQW SWILQITKCI DVHLKENAAY FQFFEEAQST 400
    EAYLKGLQDS IRKKYPCDKN MPLQHLLEQI KELEKEREKI IEYKRQVQNL 450
    VNKSKKIVQL KPRNPDYRSN KPIILRALCD YKQDQKIVHK GDECILKDNN 500
    ERSKWYVTGP GGVDMLVPSV GLIIPPPNPL AVDLSCKIEQ YYEAILALWN 550
    QLYINMKSLV SWHYCMIDIE KIRAMTIAKL KTMRQEDYMK TIEDLELHYQ 600
    DFIKNSQGSE MFGDDDKRRM QSQFTDAQKH YQTLVIQLPG HPQHQTVTKT 650
    EITHLGTCQD VNHNKVIETN RENDKQETWL LMELQKIRRQ MEHCEARMTL 700
    KNLLLAEQGS THHITVKINE LKSVQNDSQA LAEVLNQLKD MLANFRGSEK 750
    YCYLQNEIFG LFQKLENING VSDGYLNSLC SVRALLQAIL QTEDMLKVYE 800
    ARLTEEETVC LDLDKVEAYR CGLKKIKNDL NLKKSLLATM KTELQKAQQI 850
    HSQSSQQYPL YDLDLGKFTE KVTQLTDRWQ KIDKQIDFRL WDLEKQIKQL 900
    RNYRDNYQSF CKWLYDAKRR QDSLESMKFG DSNTVMRFLN EQKNLHSEIS 950
    GKRDKSEEVH KIAELCANSI KDYELQLASY TSGLETLLNI PIKRTMVQSP 1000
    SGVILQEAAD IHARYIELLT RSGDYYRFLS EMLKSLEDLK LKNTKIEVLE 1050
    EELRLARDAN SENCNKNKFL DQNLQKYQAE CSQFKAKLVS LEELKRQAEL 1100
    DGKSAKQNLD KCYGQIKELN EKITRLTYEI EDEKRRRKTV EDRFDQQKND 1150
    YDQLQKARQC EKENLSWQKL ESEKAIKEKE YEIERLRVLL QEEGARKREY 1200
    ENELAKASNR IQESKSQCTQ VVQERESLLV KIKVLEQDKA RLQRLEDELN 1250
    RAKATLEAES RVKQRLECEK QQIQNDLNQW KTQYSRKEET IRKIESEREK 1300
    SEREKNSLRS EIERLQAEIK RIEERCRRKL EDSSRETQSQ LESERCRLQK 1350
    EIEKLRQRPY GSHRETQTEY EWTVDSSKLV FDGLRKKVTA MQLYECQLID 1400
    KTTLDKLLKG KKSVEEVASE IQPFLRGAGA IAGASASPKE KYSLVEAKRK 1450
    KFITPESTVM LLEAQAATGG IIDPHRNEKL TVDNAVARDL IDFDDRQQIY 1500
    TAEKAITGFD DPFSGKTVSV SEAIKKNLID RETGMRLLEA QLASGGVVDP 1550
    VNSVFLPKDV ALARGLIDRD LYRSLNDPRD SQKNFVDPIT KKKVSYMQLR 1600
    ERCRIEPHTG LLLLSVQKRS MSFQGIRQPV TVTELVDSGI LRPSTVNELE 1650
    SGQISYDEVG ERIKDFLQGS SCIAGIYNET TKQKLGIYEA MKIGLVRPGT 1700
    ALELLEAQAA TGFIVDPVSN LRLPVEEAYK RGLVGIEFKE KLLSAERAVT 1750
    GYNDPETGNI ISLFQAMNKE LIEKGHGIRL LEAQIATGGI IDPKESHRLP 1800
    VDMAYKRGYF NEELSEILSD PSDDTKGFFD PNTEENLTYL QLKERCIKDE 1850
    ETGLCLLPLK EKKKQVQTSQ KNTLRKRRVV IVDPETNKEM SVQEAYKKGL 1900
    IDYDTFKELC EQECEWEEIT ITGSDGSTRV VLVDRKTGSQ YDIQDAIDKG 1950
    LVDRKFFDQY RSGSLSLTQF ADMISLKNGV GNSSGLGGSV NDDVFSSSRH 2000
    DSVSKISTIS SVRNLTIRSS SLSDPLEESS PIAAIFDTEN LEKISIAEGI 2050
    ERGIVDSITG QRLLEAQACT GGIIHPTTGQ KLSLQDAVNQ GLIDQDMATR 2100
    LKPAQKAFIG FEGVKGKKKM SAAEAVKEKW LPYEAGQRFL EFQFLTGGLV 2150
    DPEVHGRIST EEAIRKGFID GRAAQRLQDI SSYAKILTCP KTKLKISYKD 2200
    AMNRSMVEDI TGLRLLEAAS VSSKGLPSPY NMSAPGSRSG SRSGSRSGSR 2250
    SGSRSGSRRG SFDATGNSSY SYSYSFSSSS IGGY 2284
    Length:2,284
    Mass (Da):261,420
    Last modified:April 5, 2011 - v1
    Checksum:i8C5DB16985159434
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC140331 Genomic DNA. No translation available.
    RefSeqiXP_006516595.1. XM_006516532.1.
    UniGeneiMm.355327.

    Genome annotation databases

    EnsembliENSMUST00000127906; ENSMUSP00000117252; ENSMUSG00000054889.
    GeneIDi109620.
    KEGGimmu:109620.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC140331 Genomic DNA. No translation available.
    RefSeqi XP_006516595.1. XM_006516532.1.
    UniGenei Mm.355327.

    3D structure databases

    ProteinModelPortali E9PZW0.
    SMRi E9PZW0. Positions 190-639, 1622-1861, 2026-2221.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi E9PZW0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000127906 ; ENSMUSP00000117252 ; ENSMUSG00000054889 .
    GeneIDi 109620.
    KEGGi mmu:109620.

    Organism-specific databases

    CTDi 1832.
    MGIi MGI:109611. Dsp.

    Phylogenomic databases

    GeneTreei ENSGT00720000108730.
    KOi K10381.
    OrthoDBi EOG7TQTZV.

    Miscellaneous databases

    ChiTaRSi DSP. mouse.
    NextBioi 35554491.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9PZW0.
    Bgeei E9PZW0.

    Family and domain databases

    Gene3Di 3.90.1290.10. 5 hits.
    InterProi IPR028462. Desmoplakin.
    IPR001101. Plectin_repeat.
    IPR018159. Spectrin/alpha-actinin.
    [Graphical view ]
    PANTHERi PTHR11915:SF234. PTHR11915:SF234. 1 hit.
    Pfami PF00681. Plectin. 8 hits.
    [Graphical view ]
    SMARTi SM00250. PLEC. 18 hits.
    SM00150. SPEC. 2 hits.
    [Graphical view ]
    SUPFAMi SSF75399. SSF75399. 5 hits.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9PZW0_MOUSE
    AccessioniPrimary (citable) accession number: E9PZW0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3