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Protein
Submitted name:

Bloom syndrome protein homolog

Gene

Blm

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Bloom syndrome protein homologImported
Gene namesi
Name:BlmImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1328362 Blm

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9PZ97
PeptideAtlasiE9PZ97
PRIDEiE9PZ97

Expressioni

Gene expression databases

BgeeiENSMUSG00000030528
ExpressionAtlasiE9PZ97 baseline and differential
GenevisibleiE9PZ97 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9PZ97
SMRiE9PZ97
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini687 – 862Helicase ATP-bindingInterPro annotationAdd BLAST176
Domaini888 – 1035Helicase C-terminalInterPro annotationAdd BLAST148
Domaini1220 – 1300HRDCInterPro annotationAdd BLAST81

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili216 – 236Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0351 Eukaryota
COG0514 LUCA
GeneTreeiENSGT00550000074520
OMAiCENITEC
OrthoDBiEOG091G021X
TreeFamiTF317801

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR012532 BDHCT
IPR032439 BDHCT_assoc
IPR032437 BLM_N
IPR011545 DEAD/DEAH_box_helicase_dom
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR004589 DNA_helicase_ATP-dep_RecQ
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR010997 HRDC-like_sf
IPR002121 HRDC_dom
IPR027417 P-loop_NTPase
IPR032284 RecQ_Zn-bd
IPR018982 RQC_domain
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF08072 BDHCT, 1 hit
PF16204 BDHCT_assoc, 1 hit
PF16202 BLM_N, 1 hit
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
PF00570 HRDC, 1 hit
PF16124 RecQ_Zn_bind, 1 hit
PF09382 RQC, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SM00341 HRDC, 1 hit
SM00956 RQC, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF47819 SSF47819, 1 hit
SSF52540 SSF52540, 3 hits
TIGRFAMsiTIGR00614 recQ_fam, 1 hit
PROSITEiView protein in PROSITE
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS50967 HRDC, 1 hit

Sequencei

Sequence statusi: Complete.

E9PZ97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIMAAVPLN NLQEQLQRHS ARKLNNQPSL SKPKSLGFTF KKKTSEGDVS
60 70 80 90 100
VTSVSVVKTP ALSDKDVNVS EAFSFTESPL HKPKQQAKIE GFFKHFPGRQ
110 120 130 140 150
QSKGTCSEPS LPATVQTAQD TLCTTPKTPT AKKLPVAVFK KLEFSSSADS
160 170 180 190 200
LSDWADMDDF DMSASDAFAS LAKNPATRVS TAQKMKKTKR NFFKPPPRKA
210 220 230 240 250
NAVKTDLTPP SPECLQVDLT KESEEEEEEE EEAEGADCLS RDVICIDNDS
260 270 280 290 300
ASEELTEKDT QESQSLKAHL GAERGDSEKK SHEDEAVFHS VQNTEYFEHN
310 320 330 340 350
DNDYDIDFVP PSPEEIISTA SSSLKCSSML KDLDDSDKEK GILSTSEELL
360 370 380 390 400
SKPEEMTTHK SDAGTSKDCD AQQIRIQQQL IHVMEHICKL VDTVPTDELE
410 420 430 440 450
ALNCGTELLQ QRNIRRKLLA EAGFNGNDVR LLGSLWRHRP DSLDNTVQGD
460 470 480 490 500
SCPVGHPNKE LNSPYLLSHS PSTEECLPTT TPGKTGFSAT PKNLFERPLL
510 520 530 540 550
NSHLQKSFVS SNWAETPRME NRNESTDFPG SVLTSTTVKA QSKQAASGWN
560 570 580 590 600
VERHGQASYD IDNFNIDDFD DDDDDDDWEN IMHNFPASKS STATYPPIKE
610 620 630 640 650
GGPVKSLSER ISSAKAKFLP VVSTAQNTNL SESIQNCSDK LAQNLSSKNP
660 670 680 690 700
KHEHFQSLNF PHTKEMMKIF HKKFGLHNFR TNQLEAINAA LLGEDCFILM
710 720 730 740 750
PTGGGKSLCY QLPACVSPGV TIVISPLRSL IVDQVQKLTS FDIPATYLTG
760 770 780 790 800
DKTDSEAANI YLQLSKKDPI IKLLYVTPEK VCASNRLIST LENLYERKLL
810 820 830 840 850
ARFVIDEAHC VSQWGHDFRQ DYKRMNMLRQ KFPSVPVMAL TATANPRVQK
860 870 880 890 900
DILTQLKILR PQVFSMSFNR HNLKYYVLPK KPKKVAFDCL EWIRKHHPYD
910 920 930 940 950
SGIIYCLSRR ECDTMADTLQ REGLAALAYH AGLSDSARDE VQHKWINQDN
960 970 980 990 1000
CQVICATIAF GMGIDKPDVR FVIHASLPKS MEGYYQESGR AGRDGEISHC
1010 1020 1030 1040 1050
VLFYTYHDVT RLKRLIMMEK DGNYHTKETH VNNLYSMVHY CENITECRRI
1060 1070 1080 1090 1100
QLLAYFGEKG FNPDFCKKYP DVSCDNCCKT KDYKTKDVTD DVKNIIRFVQ
1110 1120 1130 1140 1150
EHSSSPGTRN IGPAGRFTLN MLVDIFLGSK SAKVKSGIFG KGTTYSRHNA
1160 1170 1180 1190 1200
ERLFKKLILD KILDEDLYIN ANDQPIAYVM LGTKAHSVLS GHLKVDFMET
1210 1220 1230 1240 1250
ENSSSIKKQK ALVAKVSQRE EVVKKCLGEL TEVCKLLGKV FGVHYFNIFN
1260 1270 1280 1290 1300
TATLKKLAES LSSDPEVLLQ IDGVTEDKLE KYGAEVIPVL QKYSEWTVPA
1310 1320 1330 1340 1350
EDGSPGARGA PEDTEEEEEE APVSSHYFAN QTRNERKRKK MSATHKPKRR
1360 1370 1380 1390 1400
RTSYGGFRAK GGSTTCRKTT SKSKFYGVTG SRSASCASQA TSSASRKLGI
1410
MAPPKPVNRT FLRPSYAFS
Length:1,419
Mass (Da):158,766
Last modified:April 5, 2011 - v1
Checksum:iF6BD6CBC6498AC3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110907 Genomic DNA No translation available.
RefSeqiNP_031576.4, NM_007550.4
UniGeneiMm.12932

Genome annotation databases

EnsembliENSMUST00000170315; ENSMUSP00000127995; ENSMUSG00000030528
GeneIDi12144
UCSCiuc009iaw.2 mouse

Similar proteinsi

Entry informationi

Entry nameiE9PZ97_MOUSE
AccessioniPrimary (citable) accession number: E9PZ97
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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