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Protein
Submitted name:

Prosaposin

Gene

Psap

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
ProsaposinImported
Gene namesi
Name:PsapImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:97783. Psap.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi60 ↔ 135UniRule annotation
Disulfide bondi63 ↔ 129UniRule annotation
Disulfide bondi91 ↔ 103UniRule annotation
Disulfide bondi194 ↔ 267UniRule annotation
Disulfide bondi197 ↔ 261UniRule annotation
Disulfide bondi226 ↔ 237UniRule annotation
Disulfide bondi311 ↔ 384UniRule annotation
Disulfide bondi314 ↔ 378UniRule annotation
Disulfide bondi342 ↔ 353UniRule annotation
Disulfide bondi436 ↔ 509UniRule annotation
Disulfide bondi439 ↔ 503UniRule annotation
Disulfide bondi467 ↔ 478UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Proteomic databases

MaxQBiE9PZ00.
PaxDbiE9PZ00.
PeptideAtlasiE9PZ00.
PRIDEiE9PZ00.

Expressioni

Gene expression databases

BgeeiENSMUSG00000004207.
ExpressionAtlasiE9PZ00. baseline and differential.
GenevisibleiE9PZ00. MM.

Structurei

3D structure databases

ProteinModelPortaliE9PZ00.
SMRiE9PZ00.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 55Saposin A-typeInterPro annotationAdd BLAST41
Domaini56 – 139Saposin B-typeInterPro annotationAdd BLAST84
Domaini190 – 271Saposin B-typeInterPro annotationAdd BLAST82
Domaini307 – 388Saposin B-typeInterPro annotationAdd BLAST82
Domaini432 – 513Saposin B-typeInterPro annotationAdd BLAST82
Domaini515 – 551Saposin A-typeInterPro annotationAdd BLAST37

Phylogenomic databases

eggNOGiKOG1340. Eukaryota.
ENOG410XSI5. LUCA.
GeneTreeiENSGT00530000063434.

Family and domain databases

Gene3Di1.10.225.10. 4 hits.
InterProiView protein in InterPro
IPR003119. SAP_A.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB_dom.
PfamiView protein in Pfam
PF02199. SapA. 2 hits.
PF05184. SapB_1. 4 hits.
PF03489. SapB_2. 4 hits.
PIRSFiPIRSF002431. Saposin. 1 hit.
PRINTSiPR01797. SAPOSIN.
SMARTiView protein in SMART
SM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
SUPFAMiSSF47862. SSF47862. 3 hits.
PROSITEiView protein in PROSITE
PS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.

Sequencei

Sequence statusi: Complete.

E9PZ00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGSGQTLVM PLTSPVQDPK TCSGGSAVLC RDVKTAVDCG AVKHCQQMVW
60 70 80 90 100
SKPTAKSLPC DICKTVVTEA GNLLKDNATQ EEILHYLEKT CEWIHDSSLS
110 120 130 140 150
ASCKEVVDSY LPVILDMIKG EMSNPGEVCS ALNLCQSLQE YLAEQNQKQL
160 170 180 190 200
ESNKIPEVDM ARVVAPFMSN IPLLLYPQDH PRSQPQPKAN EDVCQDCMKL
210 220 230 240 250
VSDVQTAVKT NSSFIQGFVD HVKEDCDRLG PGVSDICKNY VDQYSEVCVQ
260 270 280 290 300
MLMHMQPKEI CVLAGFCNEV KRVPMKTLVP ATETIKNILP ALEMMDPYEQ
310 320 330 340 350
NLVQAHNVIL CQTCQFVMNK FSELIVNNAT EELLVKGLSN ACALLPDPAR
360 370 380 390 400
TKCQEVVGTF GPSLLDIFIH EVNPSSLCGV IGLCAARPEL VEALEQPAPA
410 420 430 440 450
IVSALLKEPT PPKQPAQPKQ SALPAHVPPQ KNGGFCEVCK KLVLYLEHNL
460 470 480 490 500
EKNSTKEEIL AALEKGCSFL PDPYQKQCDD FVAEYEPLLL EILVEVMDPG
510 520 530 540 550
FVCSKIGVCP SAYKLLLGTE KCVWGPSYWC QNMETAARCN AVDHCKRHVW

N
Length:551
Mass (Da):60,672
Last modified:April 5, 2011 - v1
Checksum:i9EBC7879A6EA11D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079082 Genomic DNA. No translation available.
RefSeqiNP_001139596.1. NM_001146124.1.
UniGeneiMm.277498.
Mm.29978.

Genome annotation databases

EnsembliENSMUST00000165878; ENSMUSP00000126407; ENSMUSG00000004207.
GeneIDi19156.
UCSCiuc007feq.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiE9PZ00_MOUSE
AccessioniPrimary (citable) accession number: E9PZ00
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 25, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported