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Protein
Submitted name:

Chromodomain-helicase-DNA-binding protein 5

Gene

Chd5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Chromodomain-helicase-DNA-binding protein 5Imported
Gene namesi
Name:Chd5Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:3036258 Chd5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiE9PYU4
PRIDEiE9PYU4

Expressioni

Gene expression databases

BgeeiENSMUSG00000005045
ExpressionAtlasiE9PYU4 baseline and differential
GenevisibleiE9PYU4 MM

Structurei

3D structure databases

ProteinModelPortaliE9PYU4
SMRiE9PYU4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini345 – 392PHD-typeInterPro annotationAdd BLAST48
Domaini418 – 465PHD-typeInterPro annotationAdd BLAST48
Domaini499 – 556ChromoInterPro annotationAdd BLAST58
Domaini594 – 627ChromoInterPro annotationAdd BLAST34
Domaini714 – 898Helicase ATP-bindingInterPro annotationAdd BLAST185
Domaini1030 – 1195Helicase C-terminalInterPro annotationAdd BLAST166

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili65 – 85Sequence analysisAdd BLAST21
Coiled coili96 – 123Sequence analysisAdd BLAST28
Coiled coili1259 – 1279Sequence analysisAdd BLAST21
Coiled coili1815 – 1835Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IREB Eukaryota
ENOG410XNUT LUCA
GeneTreeiENSGT00760000119067

Family and domain databases

CDDicd00024 CHROMO, 2 hits
cd00079 HELICc, 1 hit
Gene3Di3.30.40.10, 2 hits
3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR028727 CHD5
IPR012957 CHD_C2
IPR012958 CHD_N
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR009462 DUF1086
IPR009463 DUF1087
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10799:SF583 PTHR10799:SF583, 3 hits
PfamiView protein in Pfam
PF08074 CHDCT2, 1 hit
PF08073 CHDNT, 1 hit
PF00385 Chromo, 1 hit
PF06461 DUF1086, 1 hit
PF06465 DUF1087, 1 hit
PF00271 Helicase_C, 1 hit
PF00628 PHD, 2 hits
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 2 hits
SM00487 DEXDc, 1 hit
SM01146 DUF1086, 1 hit
SM01147 DUF1087, 1 hit
SM00490 HELICc, 1 hit
SM00249 PHD, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF54160 SSF54160, 3 hits
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50013 CHROMO_2, 2 hits
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 2 hits

Sequencei

Sequence statusi: Complete.

E9PYU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGPLGTEEE LPRLFAEEME NEEEMSEEED GGLEGFEDFF PAEPVSLPKK
60 70 80 90 100
KPKKLKESKS SKGKRKKKEG SNDEMSDNEE DLEEKSESEG SDYSPTKKKK
110 120 130 140 150
KKLKEKKEKK EKKEKRKKRG EDEDDNDDGG LKEPKSSGQL MAEWGLDDVD
160 170 180 190 200
YLFSEDDYHT LTNYKAFSQF LRPLIAKKNP KIPMSKMMTV LGAKWREFSA
210 220 230 240 250
NNPFKGSSAA AAAAAVAAAV ETVTIAPPLA ISPQQVPQTL PIRKAKTKEG
260 270 280 290 300
KGPGVRKKNK GAKDSKKKGR GKRVAGLKFR FGGISKRKKG SSSEEDERED
310 320 330 340 350
SDLDNASIHS SSVRSECSAA LGKKNKRRRK KKRIDDGDGY ETDHQDYCEV
360 370 380 390 400
CQQGGEIILC DTCPRAYHLV CLDPELEKAP EGKWSCPHCE KEGIQWEPKD
410 420 430 440 450
DDEEEEEGGC EEEEDDHMEF CRVCKDGGEL LCCDACPSSY HLHCLNPPLP
460 470 480 490 500
EIPNGEWLCP RCTCPPLKGK VQRILHWRWT EPPAPFVVGL PGPEVEPGMP
510 520 530 540 550
PPRPLEGIPE REFFVKWAGL SYWHCSWVKE LQLELYHTVM YRNYQRKNDM
560 570 580 590 600
DEPPPFDYGS GDEDGKSEKR KNKDPLYAKM EERFYRYGIK PEWMMVHRIL
610 620 630 640 650
NHSFDKKGDI HYLIKWKDLP YDQCTWEIDE IDIPYYDNLK QAYWGHRELM
660 670 680 690 700
LGEDARLPKR LVKKGKKLKD DKQEKPPDTP IVDPTVKFDK QPWYIDATGG
710 720 730 740 750
TLHPYQLEGL NWLRFSWAQG TDTILADEMG LGKTVQTIVF LYSLYKEGHS
760 770 780 790 800
KGPYLVSAPL STIINWEREF EMWAPDFYVV TYTGDKESRS VIRENEFSFE
810 820 830 840 850
DNAIRGGKKV FRMKKEVQIK FHVLLTSYEL ITIDQAILGS IEWACLVVDE
860 870 880 890 900
AHRLKNNQSK FFRVLNSYKI DYKLLLTGTP LQNNLEELFH LLNFLTPERF
910 920 930 940 950
NNLEGFLEEF ADISKEDQIK KLHDLLGPHM LRRLKADVFK NMPAKTELIV
960 970 980 990 1000
RVELSQMQKK YYKFILTRNF EALNSKGGGN QVSLLNIMMD LKKCCNHPYL
1010 1020 1030 1040 1050
FPVAAVEAPV LPNGSYDGSS LVKSSGKLML LQKMLKKLRD EGHRVLIFSQ
1060 1070 1080 1090 1100
MTKMLDLLED FLEYEGYKYE RIDGGITGGL RQEAIDRFNA PGAQQFCFLL
1110 1120 1130 1140 1150
STRAGGLGIN LATADTVIIY DSDWNPHNDI QAFSRAHRIG QNKKVMIYRF
1160 1170 1180 1190 1200
VTRASVEERI TQVAKRKMML THLVVRPGLG SKSGSMTKQE LDDILKFGTE
1210 1220 1230 1240 1250
ELFKDDVEGD NKDVEDSSVI HYDDAAISKL LDRNQDATDD TELQNMNEYL
1260 1270 1280 1290 1300
SSFKVAQYVV REEDGVEEVE REVIKQEENV DPDYWEKLLR HHYEQQQEDL
1310 1320 1330 1340 1350
ARNLGKGKRI RKQVNYNDAS QEDQEWQDEL SDNQSEYSIG SEDEDEDFEE
1360 1370 1380 1390 1400
RPEGQSGRRQ SRRQLKSDRD KPLPPLLARV GGNIEVLGFN ARQRKAFLNA
1410 1420 1430 1440 1450
IMRWGMPPQD AFNSHWLVRD LRGKSEKEFR AYVSLFMRHL CEPGADGAET
1460 1470 1480 1490 1500
FADGVPREGL SRQHVLTRIG VMSLVRKKVQ EFEHVNGKYS TPDLVPEGAE
1510 1520 1530 1540 1550
GKKPGEVISS DPNTPVPASP AQLPPAPLGL TDKMEAQLGY TDEKESGMQK
1560 1570 1580 1590 1600
PKKSLEIQTL PTALDRVEGE DKHQSSDSKD RAREERTEEV EKAQGSPEQP
1610 1620 1630 1640 1650
LKEEVLPDKE PIPDKPELSL GHSGDFRPDD PKTEEKEPGE TQQNGDREED
1660 1670 1680 1690 1700
EEGKKEDKNG KFKFMFNIAD GGFTELHTLW QNEERAAVSS GKIYEIWHRR
1710 1720 1730 1740 1750
HDYWLLAGIV THGYARWQDI QNDPRYMILN EPFKSEIHKG NYLEMKNKFL
1760 1770 1780 1790 1800
ARRFKLLEQA LVIEEQLRRA AYLNMTQDPN HPAMALNARL AEVECLAESH
1810 1820 1830 1840 1850
QHLSKESLAG NKPANAVLHK VLNQLEELLS DMKADVTRLP SMLSRIPPVA
1860 1870 1880 1890 1900
ARLQMSERSI LSRLTNRAGD PTIQQGAFGS SQMYNNSFGP NFRGPGPGGI
1910
VNYNQMPLGP YVTDI
Length:1,915
Mass (Da):218,953
Last modified:April 5, 2011 - v1
Checksum:iA5E370E3CFB2A92C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL611985 Genomic DNA No translation available.
RefSeqiNP_083492.2, NM_029216.2
UniGeneiMm.40192

Genome annotation databases

EnsembliENSMUST00000164662; ENSMUSP00000132600; ENSMUSG00000005045
GeneIDi269610
UCSCiuc012dqc.1 mouse

Similar proteinsi

Entry informationi

Entry nameiE9PYU4_MOUSE
AccessioniPrimary (citable) accession number: E9PYU4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health