Protein Parp4 - Mus musculus (Mouse)

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E9PYK3 (E9PYK3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified March 6, 2013. Version 17. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Protein Parp4 Ensembl ENSMUSP00000124258

Gene names

Name:

Parp4 Ensembl ENSMUSP00000124258 MGI 2685589

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000124258

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1969 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 PARP catalytic domain. SAAS SAAS012317
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000124258

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell death Inferred from electronic annotation. Source: Compara inflammatory response Inferred from electronic annotation. Source: Compara protein ADP-ribosylation Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara nucleus Traceable author statement PubMed 15169895. Source: MGI spindle Traceable author statement PubMed 15169895. Source: MGI spindle microtubule Inferred from electronic annotation. Source: Compara
Molecular_function	NAD+ ADP-ribosyltransferase activity Inferred from electronic annotation. Source: Compara enzyme binding Inferred from sequence alignment PubMed 15169895. Source: MGI
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

E9PYK3 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: B1EDC5481653F93A
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FASTA

1,969

216,133

        10         20         30         40         50         60 
MTLGIFANCI FCLKVKYLPR QQKKKLQTDI KENGGKFSFL LNPQCTHVIV DSADVLSRCH 

        70         80         90        100        110        120 
LNSIQKNDVQ IANPAFIQDS VRQRRLLDVR NYDPLSPAPA APPAERSRSE VQSEYLPSDN 

       130        140        150        160        170        180 
TPEKENTEVT EVSAENVEIP PFLQDFEVVK YNILEKVGGP ETVVVELQSS QDPESCPFVI 

       190        200        210        220        230        240 
TAHFLLADQK TRRESTGKQT SEGAIEYYES YVEDLKRQGF LLQEHFTAEA TQLASEKLQA 

       250        260        270        280        290        300 
LLLEEVISSG ALSQEVSDLL EVIWTEALGH LENTLLKPVN SMSLNDVSKA EGILLLVKTA 

       310        320        330        340        350        360 
LKNGDSPGQL QKTMAEFYRL LPHRHPASEE VNLRLLAQKE DLCQLVRDMV NVCETNLSKP 

       370        380        390        400        410        420 
NPPSLAKYRA LRCKIEHVDQ NTEEFSRVRK EVLQNNRSEQ PVDILQIFRV GRVNEATEFL 

       430        440        450        460        470        480 
SKLGNVRLLF HGSPVRNILG ILSRGLLLPK VAEDRGVQRT DVGNLGSGIY FSDSLSTSIK 

       490        500        510        520        530        540 
YAHAGETDGS RLLVVCDVAL GKCVNLFKKD FSLTEAPPGY DSVHGVSETT SVPTDFQDDE 

       550        560        570        580        590        600 
FVVYKTNQVK MKYIVKFCTP GDQIKEFHPH ENTEVEEQRA EPSSVPEAGD FQLPDIKPFT 

       610        620        630        640        650        660 
NIKAGLQDAS ANPVPLDSVH IKGRVIDFVA QVIVFQTYTN QSHVPIEAKY IFPLDDKAAV 

       670        680        690        700        710        720 
CGFEAFINGK HIVGEIKEKE EARQEYREAV SQGHGAYLMD QDTPDVFTVS VGNLPPRAKV 

       730        740        750        760        770        780 
LIKITYITEL SIQSPVAIFF IPGTVAPWQQ DKALNENLQD TVETIRIKEI GAEQSFSLAM 

       790        800        810        820        830        840 
SIEMPYMIEF ISSDTHELRQ KSTDCKAVVS TVEGSSLDSG GFSLHIGLRD AYLPRMWVEK 

       850        860        870        880        890        900 
HPEKESEACM LVFQPELADV LPDLRGKNEV IICLDCSSSM EGVTFTQAKQ VALYALSLLG 

       910        920        930        940        950        960 
EEQKVNIMQF GTGYKELFSY PKCITDSKMA TEFIMSAAPS MGNTDFWKVL RYLSLLYPSE 

       970        980        990       1000       1010       1020 
GFRNILLISD GHLQSESLTL QLVKRNIQHT RVFTCAVGST ANRHILRTLS QCGAGVFEYF 

      1030       1040       1050       1060       1070       1080 
NSKSKHSWKK QIEAQMTRIR SPSCHSVSVK WQQLSRDAPE PLQAPAWVPS LFHNDRLLVY 

      1090       1100       1110       1120       1130       1140 
GFIPHCTQAT LQAFIQEKEF CTMVSTTELQ KTTGTMIHKL AARALIRDYE DGILHDDETN 

      1150       1160       1170       1180       1190       1200 
HEMKKNIMKS LIIELSKENS LITQFTSFVA VEKRDVNEIP FANVPNISEL VAKEDVDFLP 

      1210       1220       1230       1240       1250       1260 
YVSWQEKQPE ASISQTEIDS SRLKHNKLSD GHGVLQPVSV SSEVNEKPSL LLAAKKRKIK 

      1270       1280       1290       1300       1310       1320 
TIKKCSLDIS EDFEDRTAVA QSPATAQSLN FHLPLSVRPQ LKAVEQQLHG NRLEPKQRGG 

      1330       1340       1350       1360       1370       1380 
FRKLLMAKKC RNVPDSLVSS APAVTAEFSY LSACSSSSAF LSPLCDIPSS LPPHPLGGTH 

      1390       1400       1410       1420       1430       1440 
PPPPLPLPDG THLPSPLFGS THPPPPLFGG TLIPPPSSLF GGTHLPPPPP LPGGTHIPPP 

      1450       1460       1470       1480       1490       1500 
PPIPGGTLIP PSSSLFGGTH LPPPPLLSAG THIPPPPLLS AGTHLPPPPL LPAGTHIPPP 

      1510       1520       1530       1540       1550       1560 
PPITGSTHPP PPSSLFGGTH LPPPPPLPGG THIPPPPPIP GGTLIPSPSS LFGGTHLPPP 

      1570       1580       1590       1600       1610       1620 
PLLPAGTHIP PPPPITGSTH PPPPSSLFGG THLPPPPPAG TQFSLSPIGF IPPKLGPPKL 

      1630       1640       1650       1660       1670       1680 
SHSHKLVGDT NIHDSEPPLL GFKDLCSRDM GFSCGTAFSG SFASSKDFDP GKFSQGPNNI 

      1690       1700       1710       1720       1730       1740 
SFSPKAPEMG VLHQSPFCSP PKPPSAPPLV TNVLCSEAPQ SYFLNLQSAA VHQSPNNRVS 

      1750       1760       1770       1780       1790       1800 
EIIMESVESS LPSDYSSRDA SSYLALEGAE DSLLGGSSFE TDTDEAAAFI ANDLLTSIET 

      1810       1820       1830       1840       1850       1860 
SSDEECAFCD EDQESPVPWA SLFALQTENG FWKLTPELGL ILNLNVNALL TSLEEKGIRS 

      1870       1880       1890       1900       1910       1920 
LGTKGRERLL DLIATLLVLQ FLYTKLEQEG MVAKSLIKMD DAFISRNIPW AFENIKKARE 

      1930       1940       1950       1960 
WARKTEGQYP SICQRLELGK DWESATKQLL GIQPQANTSL HRILYYSQG

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000124258.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000124258.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC154731 Genomic DNA. No translation available. AC154837 Genomic DNA. No translation available.
IPI	IPI00970711.
RefSeq	NP_001139450.2. NM_001145978.2.
UniGene	Mm.379357.
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	E9PYK3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000161553; ENSMUSP00000124258; ENSMUSG00000054509.
GeneID	328417.
KEGG	mmu:328417.
Organism-specific databases
CTD	143.
MGI	MGI:2685589. Parp4.
Phylogenomic databases
GeneTree	ENSGT00530000063006.
KO	K10798.
OMA	PGGTHIP.
Gene expression databases
Bgee	E9PYK3.
Family and domain databases
Gene3D	1.20.142.10. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR009408. Formin_homology_1. IPR012317. Poly(ADP-ribose)pol_cat_dom. IPR004102. Poly(ADP-ribose)pol_reg_dom. IPR013694. VIT. IPR002035. VWF_A. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF06346. Drf_FH1. 2 hits. PF00644. PARP. 1 hit. PF08487. VIT. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 1 hit. SM00609. VIT. 1 hit. SM00327. VWA. 1 hit. [Graphical view]
SUPFAM	SSF52113. BRCT. 1 hit. SSF47587. PARP_reg. 1 hit.
PROSITE	PS50172. BRCT. 1 hit. PS51060. PARP_ALPHA_HD. 1 hit. PS51059. PARP_CATALYTIC. 1 hit. PS51468. VIT. 1 hit. PS50234. VWFA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	PARP4. mouse.
NextBio	398289.
SOURCE	Search...

Entry information

Entry name

E9PYK3_MOUSE

Accession

Primary (citable) accession number: E9PYK3

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	March 6, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

PTM databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information