##gff-version 3
E9PYH6	UniProtKB	Chain	1	1716	.	.	.	ID=PRO_0000445151;Note=Histone-lysine N-methyltransferase SETD1A	
E9PYH6	UniProtKB	Domain	84	172	.	.	.	Note=RRM;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00176	
E9PYH6	UniProtKB	Domain	1577	1694	.	.	.	Note=SET;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00190	
E9PYH6	UniProtKB	Domain	1700	1716	.	.	.	Note=Post-SET;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00155	
E9PYH6	UniProtKB	Region	60	89	.	.	.	Note=Interaction with WDR82;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Region	194	367	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Region	380	499	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Region	516	670	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Region	849	869	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Region	911	1206	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Region	1230	1259	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Region	1275	1297	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Region	1355	1427	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Region	1424	1459	.	.	.	Note=Interaction with CFP1;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Region	1459	1546	.	.	.	Note=Interaction with ASH2L%2C RBBP5 and WDR5;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Region	1480	1508	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Motif	1307	1311	.	.	.	Note=HCFC1-binding motif (HBM);Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Motif	1501	1506	.	.	.	Note=WDR5 interaction motif (WIN);Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Motif	1546	1551	.	.	.	Note=RxxxRR motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P38827	
E9PYH6	UniProtKB	Compositional bias	220	367	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	403	418	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	482	499	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	579	593	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	606	670	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	911	935	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	944	979	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	986	1008	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	1028	1080	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	1126	1151	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	1232	1252	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	1368	1384	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	1412	1426	.	.	.	Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Compositional bias	1486	1500	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
E9PYH6	UniProtKB	Binding site	1693	1693	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00190	
E9PYH6	UniProtKB	Modified residue	477	477	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Modified residue	521	521	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Modified residue	578	578	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Modified residue	930	930	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047	
E9PYH6	UniProtKB	Modified residue	1110	1110	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O15047