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E9PYH6 (E9PYH6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length1716 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214

Sequence similarities

Contains 1 SET domain. RuleBase RU004538

Contains 1 post-SET domain. RuleBase RU004541

Contains SET domain. SAAS SAAS001214

Contains post-SET domain. SAAS SAAS001214

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000047672 Ensembl ENSMUSP00000037600

Sequences

Sequence LengthMass (Da)Tools
E9PYH6 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: F578D5A2276F2D73

FASTA1,716186,060
        10         20         30         40         50         60 
MDQEGGGDGQ KAPSFQWRNY KLIVDPALDP ALRRPSQKVY RYDGVHFSVS DSKYTPVEDL 

        70         80         90        100        110        120 
QDPRCHVRSK ARDFSLPVPK FKLDEFYIGQ IPLKEVTFAR LNDNVRETFL KDMCRKYGEV 

       130        140        150        160        170        180 
EEVEILLHPR TRKHLGLARV LFTSTRGAKE TVKNLHLTSV MGNIIHAQLD IKGQQRMKYY 

       190        200        210        220        230        240 
ELIVNGSYTP QTVPTGGKAL SEKFQGSGAA AETTEARRRS SSDTAAYPAG TTVGGTPGNG 

       250        260        270        280        290        300 
TPCSQDTNFS SSRQDTPSSF GQFTPQSSQG TPYTSRGSTP YSQDSAYSSS TTSTSFKPRR 

       310        320        330        340        350        360 
SENSYQDSFS RRHFSTSSAP ATTATATSAT AAATAASSSS SSSSSSSSSS SSSSSASQFR 

       370        380        390        400        410        420 
GSDSSYPAYY ESWNRYQRHT SYPPRRATRE DPSGASFAEN TAERFPPSYT SYLAPEPNRS 

       430        440        450        460        470        480 
TDQDYRPPAS EAPPPEPPEP GGGGGGSGGG GGGGGGGGGG APSPEREEAR TPPRPASPAR 

       490        500        510        520        530        540 
SGSPAPETTN ESVPFAQHSS LDSRIEMLLK EQRSKFSFLA SDTEEEEENS SAGPGARDAG 

       550        560        570        580        590        600 
AEVPSGAGHG PCTPPPAPAN FEDVAPTGSG EPGAARESPK ANGQNQASPC SSGEDMEISD 

       610        620        630        640        650        660 
DDRGGSPPPA PTPPQQPPPP PPPPPPPPPP YLASLPLGYP PHQPAYLLPP RPDGPPPPEY 

       670        680        690        700        710        720 
PPPPPPPPPH IYDFVNSLEL MDRLGAQWGG MPMSFQMQTQ MLTRLHQLRQ GKGLTAASAG 

       730        740        750        760        770        780 
PPGGAFGEAF LPFPPPQEAA YGLPYALYTQ GQEGRGSYSR EAYHLPLPMA AEPLPSSSVS 

       790        800        810        820        830        840 
GEEARLPHRE EAEIAESKVL PSAGTVGRVL ATLVQEMKSI MQRDLNRKMV ENVAFGAFDQ 

       850        860        870        880        890        900 
WWESKEEKAK PFQNAAKQQA KEEDKEKMKL KEPGMLSLVD WAKSGGITGI EAFAFGSGLR 

       910        920        930        940        950        960 
GALRLPSFKV KRKEPSEISE ASEEKRPRPS TPAEEDEDDP EREKEAGEPG RPGTKPPKRD 

       970        980        990       1000       1010       1020 
EERGKTQGKH RKSFTLDSEG EEASQESSSE KDEDDDDEDE EDEEQEEAVD ATKKEAEASD 

      1030       1040       1050       1060       1070       1080 
GEDEDSDSSS QCSLYADSDG ENGSTSDSES GSSSSSSSSS SSSSSSSSSE SSSEEEEQSA 

      1090       1100       1110       1120       1130       1140 
VIPSASPPRE VPEPLPAPDE KPETDGLVDS PVMPLSEKET LPTQPAGPAE EPPPSVPQPP 

      1150       1160       1170       1180       1190       1200 
AEPPAGPPDA APRLDERPSS PIPLLPPPKK RRKTVSFSAA EEAPVPEPST AAPLQAKSSG 

      1210       1220       1230       1240       1250       1260 
PVSRKVPRVV ERTIRNLPLD HASLVKSWPE EVARGGRNRA GGRVRSTEEE EATESGTEVD 

      1270       1280       1290       1300       1310       1320 
LAVLADLALT PARRGLATLP TGDDSEATET SDEAERPSPL LSHILLEHNY ALAIKPPPTT 

      1330       1340       1350       1360       1370       1380 
PAPRPLEPAP ALAALFSSPA DEVLEAPEVV VAEAEEPKQQ LQQQHPEQEG EEEEEDEEEE 

      1390       1400       1410       1420       1430       1440 
SESSESSSSS SSDEEGAIRR RSLRSHTRRR RPPLPPPPPP PPSFEPRSEF EQMTILYDIW 

      1450       1460       1470       1480       1490       1500 
NSGLDLEDMS YLRLTYERLL QQTSGADWLN DTHWVQHTIT NLSTPKRKRR PQDGPREHQT 

      1510       1520       1530       1540       1550       1560 
GSARSEGYYP ISKKEKDKYL DVCPVSARQL EGGDTQGTNR VLSERRSEQR RLLSAIGTSA 

      1570       1580       1590       1600       1610       1620 
IMDSDLLKLN QLKFRKKKLR FGRSRIHEWG LFAMEPIAAD EMVIEYVGQN IRQMVADMRE 

      1630       1640       1650       1660       1670       1680 
KRYVQEGIGS SYLFRVDHDT IIDATKCGNL ARFINHCCTP NCYAKVITIE SQKKIVIYSK 

      1690       1700       1710 
QPIGVDEEIT YDYKFPLEDN KIPCLCGTES CRGSLN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC149222 Genomic DNA. No translation available.
RefSeqNP_821172.2. NM_178029.3.
UniGeneMm.435494.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000047075; ENSMUSP00000047672; ENSMUSG00000042308.
ENSMUST00000047157; ENSMUSP00000037600; ENSMUSG00000042308.
GeneID233904.
KEGGmmu:233904.
UCSCuc009jwt.1. mouse.

Organism-specific databases

CTD9739.
MGIMGI:2446244. Setd1a.

Phylogenomic databases

GeneTreeENSGT00740000115089.
KOK11422.
OMAGYLRLTY.
TreeFamTF106436.

Family and domain databases

Gene3D3.30.70.330. 1 hit.
InterProIPR024657. COMPASS_Set1_N-SET.
IPR015722. Histone-lysine_MeTfrase.
IPR012677. Nucleotide-bd_a/b_plait.
IPR003616. Post-SET_dom.
IPR000504. RRM_dom.
IPR001214. SET_dom.
[Graphical view]
PANTHERPTHR22884:SF10. PTHR22884:SF10. 1 hit.
PfamPF11764. N-SET. 1 hit.
PF00076. RRM_1. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTSM00508. PostSET. 1 hit.
SM00360. RRM. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEPS50868. POST_SET. 1 hit.
PS50102. RRM. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio381943.
PROE9PYH6.
SOURCESearch...

Entry information

Entry nameE9PYH6_MOUSE
AccessionPrimary (citable) accession number: E9PYH6
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 16, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)