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Protein
Submitted name:

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Gene

Samhd1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-8956319 Nucleobase catabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1Imported
Gene namesi
Name:Samhd1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1927468 Samhd1

PTM / Processingi

Proteomic databases

MaxQBiE9PYG9
PeptideAtlasiE9PYG9
PRIDEiE9PYG9

Expressioni

Gene expression databases

BgeeiENSMUSG00000027639
ExpressionAtlasiE9PYG9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PYG9
SMRiE9PYG9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 142SAMInterPro annotationAdd BLAST66
Domaini196 – 348HDInterPro annotationAdd BLAST153

Phylogenomic databases

eggNOGiKOG2681 Eukaryota
COG1078 LUCA
GeneTreeiENSGT00390000013867

Family and domain databases

CDDicd00077 HDc, 1 hit
InterProiView protein in InterPro
IPR003607 HD/PDEase_dom
IPR006674 HD_domain
IPR001660 SAM
IPR013761 SAM/pointed_sf
PfamiView protein in Pfam
PF01966 HD, 1 hit
PF07647 SAM_2, 1 hit
SMARTiView protein in SMART
SM00471 HDc, 1 hit
SM00454 SAM, 1 hit
SUPFAMiSSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS51831 HD, 1 hit
PS50105 SAM_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

E9PYG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSLLGCGVS AAAREPVPRY LTSQPRVSEV AMQSAPLEQP AKRPRCDGSP
60 70 80 90 100
RTPPSTPPAT ANLSADDDFQ NTDLRTWEPE DVCSFLENRG FREKKVLDIF
110 120 130 140 150
RDNKIAGSFL PFLDEDRLED LGVSSLEERK KMIECIQQLS QSRIDLMKVF
160 170 180 190 200
NDPIHGHIEF HPLLIRIIDT PQFQRLRYIK QLGGGYYVFP GASHNRFEHS
210 220 230 240 250
LGVGYLAGCL VRALAEKQPE LQISERDILC VQIAGLCHDL GHGPFSHMFD
260 270 280 290 300
GRFIPRARPE KKWKHEQGSI EMFEHLVNSN ELKLVMKNYG LVPEEDITFI
310 320 330 340 350
KEQIMGPPIT PVKDSLWPYK GRPATKSFLY EIVSNKRNGI DVDKWDYFAR
360 370 380 390 400
DCHHLGIQNN FDYKRFIKFA RICEVEYKVK EDKTYIRKVK HICSREKEVG
410 420 430 440 450
NLYDMFHTRN CLHRRAYQHK ISNLIDIMIT DAFLKADPYV EITGTAGKKF
460 470 480 490 500
RISTAIDDME AFTKLTDNIF LEVLHSTDPQ LSEAQSILRN IECRNLYKYL
510 520 530 540 550
GETQPKREKI RKEEYERLPQ EVAKAKPEKA PDVELKAEDF IVDVINVDYG
560 570 580
MEDKNPIDRV HFYCKSNSKQ AVRINKEQVM VT
Length:582
Mass (Da):67,246
Last modified:April 5, 2011 - v1
Checksum:i5EB4FCEBAB113C96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669828 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000109549; ENSMUSP00000105176; ENSMUSG00000027639
UCSCiuc008noo.1 mouse

Similar proteinsi

Entry informationi

Entry nameiE9PYG9_MOUSE
AccessioniPrimary (citable) accession number: E9PYG9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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