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Protein
Submitted name:

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Gene

Samhd1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-8956319. Nucleobase catabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1Imported
Gene namesi
Name:Samhd1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1927468. Samhd1.

PTM / Processingi

Proteomic databases

MaxQBiE9PYG9.
PaxDbiE9PYG9.
PeptideAtlasiE9PYG9.
PRIDEiE9PYG9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000027639.
ExpressionAtlasiE9PYG9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PYG9.
SMRiE9PYG9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 142SAMInterPro annotationAdd BLAST66

Phylogenomic databases

eggNOGiKOG2681. Eukaryota.
COG1078. LUCA.
GeneTreeiENSGT00390000013867.

Family and domain databases

CDDicd00077. HDc. 1 hit.
InterProiView protein in InterPro
IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR001660. SAM.
IPR013761. SAM/pointed_sf.
PfamiView protein in Pfam
PF01966. HD. 1 hit.
PF07647. SAM_2. 1 hit.
SMARTiView protein in SMART
SM00471. HDc. 1 hit.
SM00454. SAM. 1 hit.
SUPFAMiSSF47769. SSF47769. 1 hit.
PROSITEiView protein in PROSITE
PS50105. SAM_DOMAIN. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PYG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSLLGCGVS AAAREPVPRY LTSQPRVSEV AMQSAPLEQP AKRPRCDGSP
60 70 80 90 100
RTPPSTPPAT ANLSADDDFQ NTDLRTWEPE DVCSFLENRG FREKKVLDIF
110 120 130 140 150
RDNKIAGSFL PFLDEDRLED LGVSSLEERK KMIECIQQLS QSRIDLMKVF
160 170 180 190 200
NDPIHGHIEF HPLLIRIIDT PQFQRLRYIK QLGGGYYVFP GASHNRFEHS
210 220 230 240 250
LGVGYLAGCL VRALAEKQPE LQISERDILC VQIAGLCHDL GHGPFSHMFD
260 270 280 290 300
GRFIPRARPE KKWKHEQGSI EMFEHLVNSN ELKLVMKNYG LVPEEDITFI
310 320 330 340 350
KEQIMGPPIT PVKDSLWPYK GRPATKSFLY EIVSNKRNGI DVDKWDYFAR
360 370 380 390 400
DCHHLGIQNN FDYKRFIKFA RICEVEYKVK EDKTYIRKVK HICSREKEVG
410 420 430 440 450
NLYDMFHTRN CLHRRAYQHK ISNLIDIMIT DAFLKADPYV EITGTAGKKF
460 470 480 490 500
RISTAIDDME AFTKLTDNIF LEVLHSTDPQ LSEAQSILRN IECRNLYKYL
510 520 530 540 550
GETQPKREKI RKEEYERLPQ EVAKAKPEKA PDVELKAEDF IVDVINVDYG
560 570 580
MEDKNPIDRV HFYCKSNSKQ AVRINKEQVM VT
Length:582
Mass (Da):67,246
Last modified:April 5, 2011 - v1
Checksum:i5EB4FCEBAB113C96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL669828 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000109549; ENSMUSP00000105176; ENSMUSG00000027639.
UCSCiuc008noo.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiE9PYG9_MOUSE
AccessioniPrimary (citable) accession number: E9PYG9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 22, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported