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Protein
Submitted name:

G protein-coupled receptor 179

Gene

Gpr179

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptor 179Imported
Gene namesi
Name:Gpr179Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:2443409. Gpr179.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei378 – 403HelicalSequence analysisAdd BLAST26
Transmembranei415 – 438HelicalSequence analysisAdd BLAST24
Transmembranei450 – 469HelicalSequence analysisAdd BLAST20
Transmembranei490 – 510HelicalSequence analysisAdd BLAST21
Transmembranei544 – 564HelicalSequence analysisAdd BLAST21
Transmembranei608 – 628HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • dendrite terminus Source: MGI
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: GO_Central

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500324569828 – 2293Sequence analysisAdd BLAST2266

Proteomic databases

PaxDbiE9PY61.

PTM databases

iPTMnetiE9PY61.
PhosphoSitePlusiE9PY61.

Expressioni

Gene expression databases

BgeeiENSMUSG00000070337.
GenevisibleiE9PY61. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091474.

Structurei

3D structure databases

ProteinModelPortaliE9PY61.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini380 – 650G_PROTEIN_RECEP_F3_4InterPro annotationAdd BLAST271

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4418. Eukaryota.
ENOG410XXEC. LUCA.
GeneTreeiENSGT00390000010934.
InParanoidiE9PY61.
OMAiNAHTSRM.
OrthoDBiEOG091G0GG1.
PhylomeDBiE9PY61.
TreeFamiTF319114.

Family and domain databases

InterProiView protein in InterPro
IPR017978. GPCR_3_C.
IPR032964. GPR179.
PANTHERiPTHR32546:SF20. PTHR32546:SF20. 1 hit.
PfamiView protein in Pfam
PF00003. 7tm_3. 1 hit.
PROSITEiView protein in PROSITE
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PY61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGARAVVISS LAWGLLSCCF LCSGALGSQR PLRSLPPLPS QAKPRSEPMW
60 70 80 90 100
MPPKGAEAAL AFLYSGDVQR LSGANCSEKY EVRGAEGKAG VPPVLQRAAG
110 120 130 140 150
TLAQAANFLN MLLQANDIRE SSVEEDVEWY QALVRSVAEG DPKAYRALLT
160 170 180 190 200
FNPAPGASHL QLALQATRMG DETVLQDLSG NKVQEETPGE DLDRPVLQKR
210 220 230 240 250
VLTNDLRSLD SPKWPRGDGY VGDIQQVKLS PPFLECHEGQ LRPGWLVTVS
260 270 280 290 300
ATFYGLKPDL TPEVRGQVQM DIDLQSVDIN QCASGPGWYS NTHLCDLNST
310 320 330 340 350
QCVPLESQGF VLGRYLCRCR PGFYGASGSG GLEESATQAA GQFGSPQDSL
360 370 380 390 400
GKLLRCQPCP EGCTSCLDAT PCLVEEALAL RTAVLACQAC CMLAVFLSML
410 420 430 440 450
VAYRCRGSKR IRASGIVLLE TILFGSLLLY FPVFILYFKP SVFRCVALRW
460 470 480 490 500
VRLLGFAVVY GTIILKLYRV LQLFLSRTAQ RVPHPSSGQL LRRLGQLLLL
510 520 530 540 550
VLGFLVVWTA GALEPGTQHT ALVTRGHTPT GRHFYLCHHD HWDYIMVVAE
560 570 580 590 600
MLLLCWGSFL CYATRAVPSA FHEPRYMSIA LHNELLLSTA FHTARFVLVP
610 620 630 640 650
SLHPDWTLLL FFLHTHSTVT ATLALIFIPK FWKPGAPPRE EILDEVYEDE
660 670 680 690 700
LDLQRSGSYL NSSIASAWSE RSLEPGDIRD ELKKLYAQLE IRKTKEMAAN
710 720 730 740 750
NPHLPKKRGS SHQGLGRSFM RYLAEFPEAL ARQHSRDSGS LGLGSLPGSS
760 770 780 790 800
RRRLLSSSLQ ETEKPPALRK TRSTYDHHRE HNTLPFDSTL RRTLSKKASP
810 820 830 840 850
TDGRESLADG PPALGFRSAS AHNLTVGERL PRARPISLQK SLSVAAGSRE
860 870 880 890 900
KALLVASQAY LEETYRQAKE REERKKAEAA MVSPVRRPST RRLEWPLRAP
910 920 930 940 950
LSAPPSPGKS SSMDSSQTTA RPHEEAGRRL PHPPIRHQVS TPVLALSGIC
960 970 980 990 1000
LGEPRMLSPT PASTLAPILL PAPAPAPAPV LAPVSKPPQS PTLLTFICPW
1010 1020 1030 1040 1050
ENAELPGKKE NVVQEDPAGP ERSGHSPASA RTKIWRALSV AVEKRGTGES
1060 1070 1080 1090 1100
EALTEGGHVQ GEADDTDEEK PKVFSKSHSL KTPLQQGSVR SLGLAIKALT
1110 1120 1130 1140 1150
RSRSTYKEKD GGEGTPETEK GKPTEVSTGA PLRSPRLGRP KAVSKQVALA
1160 1170 1180 1190 1200
PCEDEESLQN QQNAHTSRML HVCQKEGSRE QEDRNKRVAP GPGERKVERT
1210 1220 1230 1240 1250
GKITMTTLRQ VFGEKNAEQA KESPAGYQEV PNPALQSLGS ADHRVAEVCP
1260 1270 1280 1290 1300
WEVTEPESGM DPPESVNKAK VYSWERTEGG SLEKKPSRQV LSRSWEEREK
1310 1320 1330 1340 1350
VLAESETEGV GAIPRKKPER LVRSQEAVCP WESPDSGGLS PQLVHQESDR
1360 1370 1380 1390 1400
TGGRFVVVSK GDAHPEALPS HAAKAELCLW EMSDVGEGTS TQRVQELPEE
1410 1420 1430 1440 1450
RQKSPKKATF WGERNLGGDL VSLCPWESTD FRGPSAVSLQ APGSSGSLGS
1460 1470 1480 1490 1500
GIAEVCPWEA ENIANDKKAE VCPWELGEEL AGSDGLNPGA DGKSLPGKET
1510 1520 1530 1540 1550
PSRKGCLAES GEQTVRAKPT VPQGQESVCP WEDEAPERSS PQPDKASSKA
1560 1570 1580 1590 1600
GEKLLSHGGS QVLQVCPWEA VKPEEKQATL STAEICPWEV DGQPETRTSE
1610 1620 1630 1640 1650
HPSKGEVHKD EEKMPGRARI KAQEEAEGRI QKQEAICPWE SMAPGSTPQR
1660 1670 1680 1690 1700
DTEKAQASLQ RQGSVAGRAA EICPWEVGTE VGEERTIGAE ASEARPNDAG
1710 1720 1730 1740 1750
HASTDSGSRQ VAASAPKKSE RLGSEKEVVC PWDSLSPGDS SQQPDTPNTE
1760 1770 1780 1790 1800
KLKDELQEHG SSRPIEVCPW EAEEVPTGEK AKICPWELNE GTVGKGLERE
1810 1820 1830 1840 1850
PGCEPERQRR QNLEEAGLPF QEEGTSKGDT KLCREQEGEA ICPWKPPAQV
1860 1870 1880 1890 1900
PKVSDLPLST VGQGVEGQSL EASDRASEKG ELRQDLKMGS LPEYITQVVP
1910 1920 1930 1940 1950
VDGGGASSEL QPISLQEGMV LAGSSSHPHI QCPDQPRVSS QPLVSTGDGT
1960 1970 1980 1990 2000
AEVCPWDAPD SDSDTKVEPC AQKVTGRVTE TEMSRQDEKE KSQEEKERAP
2010 2020 2030 2040 2050
ETRDHEGVAV QKMPQTSNFG KQEAVCPRES QDFGVQAATD ASDGSKGGSE
2060 2070 2080 2090 2100
KVCPWEVEEV PSIKEAEICP WEASPGAVGE GALDLGQDGE SQGEGRAERH
2110 2120 2130 2140 2150
LLKAAETVCP LEGTMSSGLF TQEDVVDTDL PKVGLHGASS PGKGLAELCV
2160 2170 2180 2190 2200
WEVTDPEGNK IKGTMADICP WEETRAQSDE SGPLALPVTQ AGVPAAPEKS
2210 2220 2230 2240 2250
VCLSVHGPLE SFLPESKSVR PDISKPPGSS RPEGVREQEP LELETGAKSV
2260 2270 2280 2290
PKPSPTETEA PESFTLTDDQ GLMASEGEAG ELSPPPDYPW DCE
Length:2,293
Mass (Da):248,715
Last modified:April 5, 2011 - v1
Checksum:iDB9EB2BA17CD6785
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596088 Genomic DNA. No translation available.
RefSeqiNP_001074689.1. NM_001081220.1.
XP_006533087.1. XM_006533024.1.
UniGeneiMm.32622.

Genome annotation databases

EnsembliENSMUST00000093942; ENSMUSP00000091474; ENSMUSG00000070337.
GeneIDi217143.
KEGGimmu:217143.
UCSCiuc007ldy.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596088 Genomic DNA. No translation available.
RefSeqiNP_001074689.1. NM_001081220.1.
XP_006533087.1. XM_006533024.1.
UniGeneiMm.32622.

3D structure databases

ProteinModelPortaliE9PY61.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091474.

PTM databases

iPTMnetiE9PY61.
PhosphoSitePlusiE9PY61.

Proteomic databases

PaxDbiE9PY61.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000093942; ENSMUSP00000091474; ENSMUSG00000070337.
GeneIDi217143.
KEGGimmu:217143.
UCSCiuc007ldy.1. mouse.

Organism-specific databases

CTDi440435.
MGIiMGI:2443409. Gpr179.

Phylogenomic databases

eggNOGiKOG4418. Eukaryota.
ENOG410XXEC. LUCA.
GeneTreeiENSGT00390000010934.
InParanoidiE9PY61.
OMAiNAHTSRM.
OrthoDBiEOG091G0GG1.
PhylomeDBiE9PY61.
TreeFamiTF319114.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000070337.
GenevisibleiE9PY61. MM.

Family and domain databases

InterProiView protein in InterPro
IPR017978. GPCR_3_C.
IPR032964. GPR179.
PANTHERiPTHR32546:SF20. PTHR32546:SF20. 1 hit.
PfamiView protein in Pfam
PF00003. 7tm_3. 1 hit.
PROSITEiView protein in PROSITE
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE9PY61_MOUSE
AccessioniPrimary (citable) accession number: E9PY61
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 7, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.