ID   E9PXZ5_MOUSE            Unreviewed;       387 AA.
AC   E9PXZ5;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Regulatory associated protein of MTOR, complex 1 {ECO:0000313|Ensembl:ENSMUSP00000124366.2};
GN   Name=Rptor {ECO:0000313|Ensembl:ENSMUSP00000124366.2,
GN   ECO:0000313|MGI:MGI:1921620};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000124366.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000124366.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000124366.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0007829|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000124366.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000124366.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; E9PXZ5; -.
DR   SMR; E9PXZ5; -.
DR   MaxQB; E9PXZ5; -.
DR   PeptideAtlas; E9PXZ5; -.
DR   ProteomicsDB; 323027; -.
DR   Antibodypedia; 4616; 661 antibodies from 44 providers.
DR   Ensembl; ENSMUST00000147781.8; ENSMUSP00000124366.2; ENSMUSG00000025583.17.
DR   UCSC; uc007mqx.1; mouse.
DR   AGR; MGI:1921620; -.
DR   MGI; MGI:1921620; Rptor.
DR   VEuPathDB; HostDB:ENSMUSG00000025583; -.
DR   GeneTree; ENSGT00640000091541; -.
DR   HOGENOM; CLU_061814_0_0_1; -.
DR   ChiTaRS; Rptor; mouse.
DR   Proteomes; UP000000589; Chromosome 11.
DR   Bgee; ENSMUSG00000025583; Expressed in embryonic post-anal tail and 229 other cell types or tissues.
DR   ExpressionAtlas; E9PXZ5; baseline and differential.
DR   GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR   GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR   InterPro; IPR004083; Raptor.
DR   InterPro; IPR029347; Raptor_N.
DR   PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR   PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR   Pfam; PF14538; Raptor_N; 1.
DR   PRINTS; PR01547; YEAST176DUF.
DR   SMART; SM01302; Raptor_N; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:E9PXZ5,
KW   ECO:0007829|MaxQB:E9PXZ5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   DOMAIN          54..207
FT                   /note="Raptor N-terminal CASPase-like"
FT                   /evidence="ECO:0000259|SMART:SM01302"
SQ   SEQUENCE   387 AA;  44008 MW;  5820C9A329E8128F CRC64;
     MESEMLQSPL MGLGEEDEAD LTDWNLPLAF MKKRHCEKIE GSKSLAQSWR MKDRMKTVSV
     ALVLCLNVGV DPPDVVKTTP CARLECWIDP LSMGPQKALE TIGANLQKQY ENWQPRARYK
     QSLDPTVDEV KKLCTSLRRN AKEERVLFHY NGHGVPRPTV NGEVWVFNKN YTQYIPLSIY
     DLQTWMGSPS IFVYDCSNAG LIVKSFKQFA LQREQELEVA AINPNHPLAQ MPLPPSMKNC
     IQLAACEAHE LLPMIPDLPA DLFTSCLTTP IKIALRWFCM QKCVSLVPGV TLDLIEKIPG
     RLNDRRTPLG ELNWIFTAIT DTIAWNVLPR DLFQKLFRQD LLVASLFRNF LLAERIMRSY
     NCTPVSSPRL PPTYMHAMCT AHSLPSS
//