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E9PXG5

- E9PXG5_MOUSE

UniProt

E9PXG5 - E9PXG5_MOUSE

Protein
Submitted name:

Clusterin

Gene

Clu

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. chaperone-mediated protein folding Source: Ensembl
    2. intrinsic apoptotic signaling pathway Source: Ensembl
    3. negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
    4. negative regulation of protein homooligomerization Source: Ensembl
    5. positive regulation of apoptotic process Source: Ensembl
    6. positive regulation of intrinsic apoptotic signaling pathway Source: Ensembl
    7. positive regulation of NF-kappaB transcription factor activity Source: Ensembl
    8. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
    9. positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: Ensembl
    10. protein stabilization Source: Ensembl
    11. response to misfolded protein Source: Ensembl
    12. response to virus Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ClusterinImported
    Gene namesi
    Name:CluImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:88423. Clu.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular matrix Source: Ensembl
    2. mitochondrion Source: Ensembl
    3. perinuclear region of cytoplasm Source: Ensembl
    4. spherical high-density lipoprotein particle Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiE9PXG5.
    BgeeiE9PXG5.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000063668.

    Family and domain databases

    InterProiIPR016016. Clusterin.
    IPR000753. Clusterin-like.
    IPR016014. Clusterin_N.
    [Graphical view]
    PANTHERiPTHR10970:SF1. PTHR10970:SF1. 1 hit.
    PfamiPF01093. Clusterin. 1 hit.
    [Graphical view]
    SMARTiSM00030. CLb. 1 hit.
    [Graphical view]
    PROSITEiPS00492. CLUSTERIN_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    E9PXG5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKILLLCVAL LLIWDNGMVL GEQEVSDNEL QELSTQGSRY INKEIQNAVQ    50
    GVKHIKTLIE KTNAERKSLL NSLEEAKKKK EDALEDTRDS EMKLKAFPEV 100
    CNETMMALWE ECKPCLKHTC MKFYARVCRS GSGLVGQQLE EFLNQSSPFY 150
    FWMNGDRIDS LLESDRQQSQ VLDAMQDSFA RASGIIDTLF QDRFFARELH 200
    DPHYFSPIGF PHKRPHFLYP KSRLVRSLMS PSH 233
    Length:233
    Mass (Da):26,937
    Last modified:April 5, 2011 - v1
    Checksum:iE3A062E85A3E3FA0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei233 – 2331Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC126444 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000127387; ENSMUSP00000114720; ENSMUSG00000022037.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC126444 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000127387 ; ENSMUSP00000114720 ; ENSMUSG00000022037 .

    Organism-specific databases

    MGIi MGI:88423. Clu.

    Phylogenomic databases

    GeneTreei ENSGT00530000063668.

    Miscellaneous databases

    ChiTaRSi CLU. mouse.
    NextBioi 35554157.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9PXG5.
    Bgeei E9PXG5.

    Family and domain databases

    InterProi IPR016016. Clusterin.
    IPR000753. Clusterin-like.
    IPR016014. Clusterin_N.
    [Graphical view ]
    PANTHERi PTHR10970:SF1. PTHR10970:SF1. 1 hit.
    Pfami PF01093. Clusterin. 1 hit.
    [Graphical view ]
    SMARTi SM00030. CLb. 1 hit.
    [Graphical view ]
    PROSITEi PS00492. CLUSTERIN_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9PXG5_MOUSE
    AccessioniPrimary (citable) accession number: E9PXG5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3