E9PXG2 (E9PXG2_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Disks large homolog 4 Ensembl ENSMUSP00000126707

Gene names

Name:

Dlg4 Ensembl ENSMUSP00000126707 MGI 1277959

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000126707

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	107 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 PDZ (DHR) domain. RuleBase RU003354
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000126707

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering Inferred from electronic annotation. Source: Compara dendritic spine morphogenesis Inferred from electronic annotation. Source: Compara establishment of protein localization Inferred from electronic annotation. Source: Compara negative regulation of receptor internalization Inferred from electronic annotation. Source: Compara positive regulation of excitatory postsynaptic membrane potential Inferred from electronic annotation. Source: Compara positive regulation of synaptic transmission Inferred from electronic annotation. Source: Compara protein complex assembly Inferred from electronic annotation. Source: Compara receptor localization to synapse Inferred from electronic annotation. Source: Compara regulation of N-methyl-D-aspartate selective glutamate receptor activity Inferred from electronic annotation. Source: Compara regulation of long-term neuronal synaptic plasticity Inferred from genetic interaction PubMed 12427827. Source: MGI synaptic vesicle maturation Inferred from direct assay PubMed 15603741. Source: MGI
Cellular_component	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Inferred from direct assay PubMed 15883194PubMed 22632720. Source: MGI cell junction Inferred from direct assay PubMed 21920314. Source: MGI cortical cytoskeleton Inferred from electronic annotation. Source: Compara dendrite cytoplasm Inferred from electronic annotation. Source: Compara excitatory synapse Inferred from electronic annotation. Source: Compara extrinsic to internal side of plasma membrane Inferred from direct assay PubMed 11483650. Source: MGI juxtaparanode region of axon Inferred from direct assay PubMed 19109503. Source: MGI neuron projection terminus Inferred from direct assay PubMed 12115694. Source: MGI postsynaptic density Inferred from direct assay PubMed 15317856PubMed 15748150PubMed 17018287PubMed 17093100. Source: MGI postsynaptic membrane Inferred from electronic annotation. Source: Compara synaptic vesicle Inferred from direct assay PubMed 16520334. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	107	1	Ensembl ENSMUSP00000126707

Sequences

	Sequence		Length	Mass (Da)
	E9PXG2 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: A2BCC3E525C15E56	FASTA	107	11,584
	10 20 30 40 50 60 MEYEEITLER GNSGLGFSIA GGTDNPHIGD DPSIFITKII PGGAAAQDGR LRVNDSILFV 70 80 90 100 NEVDVREVTH SAAVEALKEA GSIVRLYVMR RKPPAEKIIE IKLIKGP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000126707.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000126707.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL596185 Genomic DNA. No translation available.
IPI	IPI01016164.
3D structure databases
ProteinModelPortal	E9PXG2.
SMR	E9PXG2. Positions 2-94.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000133140; ENSMUSP00000126707; ENSMUSG00000020886.
Organism-specific databases
MGI	MGI:1277959. Dlg4.
Phylogenomic databases
GeneTree	ENSGT00660000095130.
Gene expression databases
ArrayExpress	E9PXG2.
Bgee	E9PXG2.
Family and domain databases
InterPro	IPR001478. PDZ. [Graphical view]
Pfam	PF00595. PDZ. 1 hit. [Graphical view]
SMART	SM00228. PDZ. 1 hit. [Graphical view]
SUPFAM	SSF50156. PDZ. 1 hit.
PROSITE	PS50106. PDZ. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	DLG4. mouse.
NextBio	35554155.
SOURCE	Search...

Entry information

Entry name

E9PXG2_MOUSE

Accession

Primary (citable) accession number: E9PXG2

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	April 3, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)