Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E9PX58

- E9PX58_MOUSE

UniProt

E9PX58 - E9PX58_MOUSE

Protein

Interleukin

Gene

Il21

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
  1. Functioni

    GO - Molecular functioni

    1. cytokine receptor binding Source: MGI

    GO - Biological processi

    1. immune response Source: InterPro
    2. positive regulation of interferon-gamma biosynthetic process Source: MGI
    3. positive regulation of interleukin-10 production Source: MGI
    4. positive regulation of natural killer cell cytokine production Source: MGI
    5. positive regulation of natural killer cell differentiation Source: MGI
    6. positive regulation of natural killer cell mediated cytotoxicity Source: MGI

    Keywords - Molecular functioni

    CytokineUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    InterleukinUniRule annotation
    Gene namesi
    Name:Il21Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 3

    Organism-specific databases

    MGIiMGI:1890474. Il21.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: UniProtKB-KW

    Expressioni

    Gene expression databases

    ArrayExpressiE9PX58.
    BgeeiE9PX58.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PX58.
    SMRiE9PX58. Positions 23-140.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the IL-15/IL-21 family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00390000010494.
    OMAiEQSAFSC.

    Family and domain databases

    InterProiIPR009079. 4_helix_cytokine-like_core.
    IPR003443. IL-15/IL-21_fam.
    IPR028151. IL-21.
    [Graphical view]
    PANTHERiPTHR14356. PTHR14356. 1 hit.
    PfamiPF02372. IL15. 1 hit.
    [Graphical view]
    SUPFAMiSSF47266. SSF47266. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E9PX58-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERTLVCLVV IFLGTVAHKS SPQGPDRLLI RLRHLIDIVE QLKIYENDLD    50
    PELLSAPQDV KGHCEHAAFA CFQKAKLKPS NPGNNKTFII DLVAQLRRRL 100
    PARRGGKKQK HIAKCPSCDS YEKRTPKEFL ERLKWLLQKV CTLNAFLSLP 150
    CCVRVPPVPS DS 162
    Length:162
    Mass (Da):18,364
    Last modified:April 5, 2011 - v1
    Checksum:iC1B64A6EE7D95074
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL662823 Genomic DNA. No translation available.
    RefSeqiNP_001277970.1. NM_001291041.1.
    UniGeneiMm.157689.

    Genome annotation databases

    EnsembliENSMUST00000161015; ENSMUSP00000124668; ENSMUSG00000027718.
    GeneIDi60505.
    UCSCiuc008pak.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL662823 Genomic DNA. No translation available.
    RefSeqi NP_001277970.1. NM_001291041.1.
    UniGenei Mm.157689.

    3D structure databases

    ProteinModelPortali E9PX58.
    SMRi E9PX58. Positions 23-140.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000161015 ; ENSMUSP00000124668 ; ENSMUSG00000027718 .
    GeneIDi 60505.
    UCSCi uc008pak.1. mouse.

    Organism-specific databases

    MGIi MGI:1890474. Il21.

    Phylogenomic databases

    GeneTreei ENSGT00390000010494.
    OMAi EQSAFSC.

    Miscellaneous databases

    NextBioi 35554109.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9PX58.
    Bgeei E9PX58.

    Family and domain databases

    InterProi IPR009079. 4_helix_cytokine-like_core.
    IPR003443. IL-15/IL-21_fam.
    IPR028151. IL-21.
    [Graphical view ]
    PANTHERi PTHR14356. PTHR14356. 1 hit.
    Pfami PF02372. IL15. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47266. SSF47266. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9PX58_MOUSE
    AccessioniPrimary (citable) accession number: E9PX58
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3