E9PX58 (E9PX58_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Interleukin RuleBase RU003453

Gene names

Name:

Il21 Ensembl ENSMUSP00000124668 MGI 1890474

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000124668

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Belongs to the IL-15/IL-21 family. RuleBase RU003453
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000124668

Ontologies

Keywords
Molecular function	Cytokine RuleBase RU003453
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	immune response Inferred from electronic annotation. Source: InterPro positive regulation of interferon-gamma biosynthetic process Inferred from direct assay PubMed 14764669. Source: MGI positive regulation of interleukin-10 production Inferred from direct assay PubMed 14764669. Source: MGI positive regulation of natural killer cell cytokine production Inferred from direct assay PubMed 14764669. Source: MGI positive regulation of natural killer cell differentiation Inferred from direct assay PubMed 14764669. Source: MGI positive regulation of natural killer cell mediated cytotoxicity Inferred from direct assay PubMed 14764669. Source: MGI
Cellular_component	extracellular space Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	cytokine receptor binding Inferred from direct assay PubMed 11081504. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PX58 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: C1B64A6EE7D95074	FASTA	162	18,364
	10 20 30 40 50 60 MERTLVCLVV IFLGTVAHKS SPQGPDRLLI RLRHLIDIVE QLKIYENDLD PELLSAPQDV 70 80 90 100 110 120 KGHCEHAAFA CFQKAKLKPS NPGNNKTFII DLVAQLRRRL PARRGGKKQK HIAKCPSCDS 130 140 150 160 YEKRTPKEFL ERLKWLLQKV CTLNAFLSLP CCVRVPPVPS DS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000124668.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000124668.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL662823 Genomic DNA. No translation available.
IPI	IPI00969942.
3D structure databases
ProteinModelPortal	E9PX58.
SMR	E9PX58. Positions 23-140.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000161015; ENSMUSP00000124668; ENSMUSG00000027718.
Organism-specific databases
MGI	MGI:1890474. Il21.
Phylogenomic databases
GeneTree	ENSGT00390000010494.
OMA	DVKRHCE.
Gene expression databases
ArrayExpress	E9PX58.
Bgee	E9PX58.
Family and domain databases
InterPro	IPR003443. Interleukin_15-like. [Graphical view]
Pfam	PF02372. IL15. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35554109.
SOURCE	Search...

Entry information

Entry name

E9PX58_MOUSE

Accession

Primary (citable) accession number: E9PX58

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)