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Protein
Submitted name:

Glutamate receptor 4

Gene

Gria4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Source: MGI
  2. extracellular-glutamate-gated ion channel activity Source: GO_Central

GO - Biological processi

  1. ionotropic glutamate receptor signaling pathway Source: MGI
  2. ion transmembrane transport Source: GO_Central
  3. synaptic transmission, glutamatergic Source: GO_Central
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate receptor 4Imported
Gene namesi
Name:Gria4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:95811. Gria4.

Subcellular locationi

GO - Cellular componenti

  1. alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Source: MGI
  2. dendrite Source: GO_Central
  3. postsynaptic membrane Source: GO_Central
  4. synapse Source: MGI
  5. vesicle Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiE9PX01.

Expressioni

Gene expression databases

BgeeiE9PX01.
ExpressionAtlasiE9PX01. baseline and differential.

Structurei

3D structure databases

SMRiE9PX01. Positions 23-401.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118920.
KOiK05200.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF01094. ANF_receptor. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PX01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIICRQIVL LFSGFWGLAM GAFPSSVQIG GLFIRNTDQE YTAFRLAIFL
60 70 80 90 100
HNTSPNASEA PFNLVPHVDN IETANSFAVT NAFCSQYSRG VFAIFGLYDK
110 120 130 140 150
RSVHTLTSFC SALHISLITP SFPTEGESQF VLQLRPSLRG ALLSLLDHYE
160 170 180 190 200
WNCFVFLYDT DRGYSILQAI MEKAGQNGWH VSAICVENFN DVSYRQLLEE
210 220 230 240 250
LDRRQEKKFV IDCEIERLQN ILEQIVSVGK HVKGYHYIIA NLGFKDISLE
260 270 280 290 300
RFIHGGANVT GFQLVDFNTP MVTKLMDRWK KLDQREYPGS ETPPKYTSAL
310 320 330 340 350
TYDGVLVMAE TFRSLRRQKI DISRRGNAGD CLANPAAPWG QGIDMERTLK
360 370 380 390 400
QVRIQGLTGN VQFDHYGRRV NYTMDVFELK STGPRKVGYW NDMDKLVLIQ
410 420 430
DAPTLGNDTA AIENRTVVVT TIMPLMKNPI LRN
Length:433
Mass (Da):49,122
Last modified:April 4, 2011 - v1
Checksum:iCDD14343C5D280D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127269 Genomic DNA. No translation available.
AC134592 Genomic DNA. No translation available.
AC141562 Genomic DNA. No translation available.
AC156503 Genomic DNA. No translation available.
CT030685 Genomic DNA. No translation available.
RefSeqiNP_001106652.1. NM_001113181.1.
UniGeneiMm.209263.

Genome annotation databases

EnsembliENSMUST00000163309; ENSMUSP00000129316; ENSMUSG00000025892.
GeneIDi14802.
KEGGimmu:14802.
UCSCiuc009obq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127269 Genomic DNA. No translation available.
AC134592 Genomic DNA. No translation available.
AC141562 Genomic DNA. No translation available.
AC156503 Genomic DNA. No translation available.
CT030685 Genomic DNA. No translation available.
RefSeqiNP_001106652.1. NM_001113181.1.
UniGeneiMm.209263.

3D structure databases

SMRiE9PX01. Positions 23-401.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiE9PX01.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000163309; ENSMUSP00000129316; ENSMUSG00000025892.
GeneIDi14802.
KEGGimmu:14802.
UCSCiuc009obq.2. mouse.

Organism-specific databases

CTDi2893.
MGIiMGI:95811. Gria4.

Phylogenomic databases

GeneTreeiENSGT00760000118920.
KOiK05200.

Miscellaneous databases

ChiTaRSiGria4. mouse.
NextBioi286965.
SOURCEiSearch...

Gene expression databases

BgeeiE9PX01.
ExpressionAtlasiE9PX01. baseline and differential.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF01094. ANF_receptor. 1 hit.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (APR-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9PX01_MOUSE
AccessioniPrimary (citable) accession number: E9PX01
Entry historyi
Integrated into UniProtKB/TrEMBL: April 4, 2011
Last sequence update: April 4, 2011
Last modified: March 31, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.