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Protein
Submitted name:

Epoxide hydrolase 1

Gene

Ephx1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Protein family/group databases

ESTHERimouse-EPHX1. Epoxide_hydrolase.

Names & Taxonomyi

Protein namesi
Submitted name:
Epoxide hydrolase 1Imported
Gene namesi
Name:Ephx1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:95405. Ephx1.

PTM / Processingi

Proteomic databases

EPDiE9PWK1.
MaxQBiE9PWK1.
PaxDbiE9PWK1.

Expressioni

Gene expression databases

BgeeiE9PWK1.
ExpressionAtlasiE9PWK1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047551.

Structurei

3D structure databases

ProteinModelPortaliE9PWK1.
SMRiE9PWK1. Positions 27-435.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 157110EHNInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2565. Eukaryota.
COG0596. LUCA.
GeneTreeiENSGT00390000002210.
KOiK01253.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000639. Epox_hydrolase-like.
IPR010497. Epoxide_hydro_N.
IPR016292. Epoxide_hydrolase.
[Graphical view]
PfamiPF06441. EHN. 1 hit.
[Graphical view]
PIRSFiPIRSF001112. Epoxide_hydrolase. 1 hit.
PRINTSiPR00412. EPOXHYDRLASE.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PWK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLELILASV LGFVIYWFVS RDKEETLPLE DGWWGPGSKP SAKEDESIRP
60 70 80 90 100
FKVETSDEEI KDLHQRIDRF RASPPLEGSR FHYGFNSSYL KKVVSFWRNE
110 120 130 140 150
FDWRKQVEIL NQYPHFKTKI EGLDIHFIHV KPPQLPSGRT PKPLLMVHGW
160 170 180 190 200
PGSFYEFYKI IPLLTDPKTH GLSDEHVFEV ICPSIPGYGF SEASSKKGLN
210 220 230 240 250
SVATARIFYK LMSRLGFQKF YIQGGDWGSL ICTNIAQMVP KNIYSLTPLL
260 270 280 290 300
GQRFGRFLGY TEKDLELLYP FKEKVFYNIM RESGYLHIQA TKPDTVGCAL
310 320 330 340 350
NDSPVGLAAY ILEKFSTWTK SEYRELEDGG LERKFSLEDL LTNIMIYWTT
360 370 380 390 400
GTIVSSQRFY KENLGQGVMV HRHEGMKVFV PTGYSAFPSE ILHAPEKWVK
410 420 430 440
VKYPKLISYS YMERGGHFAA FEEPKLLAQD IRKFVSLAEL Q
Length:441
Mass (Da):50,970
Last modified:April 5, 2011 - v1
Checksum:i5ED8F3E58FDDDE6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117673 Genomic DNA. No translation available.
RefSeqiNP_001299847.1. NM_001312918.1.
UniGeneiMm.9075.

Genome annotation databases

EnsembliENSMUST00000111068; ENSMUSP00000106697; ENSMUSG00000038776.
GeneIDi13849.
KEGGimmu:13849.
UCSCiuc011wxq.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117673 Genomic DNA. No translation available.
RefSeqiNP_001299847.1. NM_001312918.1.
UniGeneiMm.9075.

3D structure databases

ProteinModelPortaliE9PWK1.
SMRiE9PWK1. Positions 27-435.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047551.

Protein family/group databases

ESTHERimouse-EPHX1. Epoxide_hydrolase.

Proteomic databases

EPDiE9PWK1.
MaxQBiE9PWK1.
PaxDbiE9PWK1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000111068; ENSMUSP00000106697; ENSMUSG00000038776.
GeneIDi13849.
KEGGimmu:13849.
UCSCiuc011wxq.1. mouse.

Organism-specific databases

CTDi2052.
MGIiMGI:95405. Ephx1.

Phylogenomic databases

eggNOGiKOG2565. Eukaryota.
COG0596. LUCA.
GeneTreeiENSGT00390000002210.
KOiK01253.

Miscellaneous databases

ChiTaRSiEphx1. mouse.
NextBioi35554029.
SOURCEiSearch...

Gene expression databases

BgeeiE9PWK1.
ExpressionAtlasiE9PWK1. baseline and differential.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000639. Epox_hydrolase-like.
IPR010497. Epoxide_hydro_N.
IPR016292. Epoxide_hydrolase.
[Graphical view]
PfamiPF06441. EHN. 1 hit.
[Graphical view]
PIRSFiPIRSF001112. Epoxide_hydrolase. 1 hit.
PRINTSiPR00412. EPOXHYDRLASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  4. "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
    Rardin M.J., Newman J.C., Held J.M., Cusack M.P., Sorensen D.J., Li B., Schilling B., Mooney S.D., Kahn C.R., Verdin E., Gibson B.W.
    Proc. Natl. Acad. Sci. U.S.A. 110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE9PWK1_MOUSE
AccessioniPrimary (citable) accession number: E9PWK1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 11, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.