Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E9PWE4

- E9PWE4_MOUSE

UniProt

E9PWE4 - E9PWE4_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Transcription factor E2-alpha

Gene

Tcf3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. chromatin binding Source: MGI
  2. DNA binding Source: MGI
  3. protein heterodimerization activity Source: MGI
  4. protein homodimerization activity Source: MGI
  5. sequence-specific DNA binding Source: MGI
  6. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. cell development Source: MGI
  2. histone H3 acetylation Source: MGI
  3. histone H4 acetylation Source: MGI
  4. immunoglobulin V(D)J recombination Source: MGI
  5. lymphocyte differentiation Source: MGI
  6. natural killer cell differentiation Source: MGI
  7. Peyer's patch development Source: MGI
  8. positive regulation of gene expression Source: MGI
  9. positive regulation of transcription, DNA-templated Source: MGI
  10. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  11. protein stabilization Source: MGI
  12. regulation of transcription, DNA-templated Source: MGI
  13. regulation of transcription from RNA polymerase II promoter Source: MGI
  14. response to drug Source: MGI
  15. response to lipopolysaccharide Source: MGI
  16. T cell differentiation in thymus Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor E2-alphaImported
Gene namesi
Name:Tcf3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 10

Organism-specific databases

MGIiMGI:98510. Tcf3.

Subcellular locationi

GO - Cellular componenti

  1. nuclear nucleosome Source: MGI
  2. nucleus Source: MGI
  3. transcription factor complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9PWE4.
ExpressionAtlasiE9PWE4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PWE4.
SMRiE9PWE4. Positions 536-608.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00510000046438.
KOiK09063.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PWE4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMNQSQRMAP VGSDKELSDL LDFSMMFPLP VANGKSRPAS LGGTQFAGSG
60 70 80 90 100
LEDRPSSGSW GSSDQNSSSF DPSRTYSEGA HFSDSHSSLP PSTFLGAGLG
110 120 130 140 150
GKGSERNAYA TFGRDTSVGT LSQAGFLPGE LSLSSPGPLS PSGIKSSSQY
160 170 180 190 200
YPSFPSNPRR RAADGGLDTQ PKKVRKVPPG LPSSVYPPSS GDSYSRDAAA
210 220 230 240 250
YPSAKTPSSA YPSPFYVADG SLHPSAELWS TPSQVGFGPM LGDGSSPLPL
260 270 280 290 300
APGSSSVGSG TFGGLQQQDR MGYQLHGSEV NGSLPAVSSF SAAPGTYSGT
310 320 330 340 350
SGHTPPVSGA AAESLLGTRG TTASSSGDAL GKALASIYSP DHSSNNFSPS
360 370 380 390 400
PSTPVGSPQG LPGTSQWPRA GAPSALSPNY DAGLHGLQSK MEDRLDEAIH
410 420 430 440 450
VLRSHAVGTA SDLHGLLPGH GALTTSFTGP MSLGGRHAGL VGGSHPEEGL
460 470 480 490 500
TSGASLLHNH ASLPSQPSSL PDLSQRPPDS YSGLGRAGTT AGASEIKREE
510 520 530 540 550
KEDEEIASVA DAEEDKKDLK VPRTRTSTDE VLSLEEKDLR DRERRMANNA
560 570 580 590 600
RERVRVRDIN EAFRELGRMC QLHLKSDKAQ TKLLILQQAV QVILGLEQQV
610 620 630 640
RERNLNPKAA CLKRREEEKV SGVVGDPQLA LSAAHPGLGE AHNPAGHL
Length:648
Mass (Da):67,458
Last modified:April 5, 2011 - v1
Checksum:i601A68FD940D7506
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152062 Genomic DNA. No translation available.
RefSeqiNP_001157625.1. NM_001164153.1.
UniGeneiMm.3406.

Genome annotation databases

EnsembliENSMUST00000105340; ENSMUSP00000100977; ENSMUSG00000020167.
GeneIDi21423.
KEGGimmu:21423.
UCSCiuc007gdl.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152062 Genomic DNA. No translation available.
RefSeqi NP_001157625.1. NM_001164153.1.
UniGenei Mm.3406.

3D structure databases

ProteinModelPortali E9PWE4.
SMRi E9PWE4. Positions 536-608.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000105340 ; ENSMUSP00000100977 ; ENSMUSG00000020167 .
GeneIDi 21423.
KEGGi mmu:21423.
UCSCi uc007gdl.2. mouse.

Organism-specific databases

CTDi 6929.
MGIi MGI:98510. Tcf3.

Phylogenomic databases

GeneTreei ENSGT00510000046438.
KOi K09063.

Miscellaneous databases

ChiTaRSi Tcf3. mouse.
NextBioi 300742.
SOURCEi Search...

Gene expression databases

Bgeei E9PWE4.
ExpressionAtlasi E9PWE4. baseline and differential.

Family and domain databases

Gene3Di 4.10.280.10. 1 hit.
InterProi IPR011598. bHLH_dom.
[Graphical view ]
Pfami PF00010. HLH. 1 hit.
[Graphical view ]
SMARTi SM00353. HLH. 1 hit.
[Graphical view ]
SUPFAMi SSF47459. SSF47459. 1 hit.
PROSITEi PS50888. BHLH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9PWE4_MOUSE
AccessioniPrimary (citable) accession number: E9PWE4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 26, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3