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E9PWE4

- E9PWE4_MOUSE

UniProt

E9PWE4 - E9PWE4_MOUSE

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Protein
Submitted name: Transcription factor E2-alpha
Gene
Tcf3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. chromatin binding Source: MGI
  3. protein binding Source: MGI
  4. protein heterodimerization activity Source: MGI
  5. protein homodimerization activity Source: MGI
  6. sequence-specific DNA binding Source: MGI
  7. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. Peyer's patch development Source: MGI
  2. T cell differentiation in thymus Source: MGI
  3. cell development Source: MGI
  4. histone H3 acetylation Source: MGI
  5. histone H4 acetylation Source: MGI
  6. immunoglobulin V(D)J recombination Source: MGI
  7. lymphocyte differentiation Source: MGI
  8. natural killer cell differentiation Source: MGI
  9. positive regulation of gene expression Source: MGI
  10. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  11. positive regulation of transcription, DNA-templated Source: MGI
  12. protein stabilization Source: MGI
  13. regulation of transcription from RNA polymerase II promoter Source: MGI
  14. regulation of transcription, DNA-templated Source: MGI
  15. response to drug Source: MGI
  16. response to lipopolysaccharide Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor E2-alphaImported
Gene namesi
Name:Tcf3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 10

Organism-specific databases

MGIiMGI:98510. Tcf3.

Subcellular locationi

GO - Cellular componenti

  1. nuclear nucleosome Source: MGI
  2. nucleus Source: MGI
  3. transcription factor complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiE9PWE4.
BgeeiE9PWE4.

Structurei

3D structure databases

ProteinModelPortaliE9PWE4.
SMRiE9PWE4. Positions 536-608.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00510000046438.
KOiK09063.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PWE4-1 [UniParc]FASTAAdd to Basket

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MMNQSQRMAP VGSDKELSDL LDFSMMFPLP VANGKSRPAS LGGTQFAGSG    50
LEDRPSSGSW GSSDQNSSSF DPSRTYSEGA HFSDSHSSLP PSTFLGAGLG 100
GKGSERNAYA TFGRDTSVGT LSQAGFLPGE LSLSSPGPLS PSGIKSSSQY 150
YPSFPSNPRR RAADGGLDTQ PKKVRKVPPG LPSSVYPPSS GDSYSRDAAA 200
YPSAKTPSSA YPSPFYVADG SLHPSAELWS TPSQVGFGPM LGDGSSPLPL 250
APGSSSVGSG TFGGLQQQDR MGYQLHGSEV NGSLPAVSSF SAAPGTYSGT 300
SGHTPPVSGA AAESLLGTRG TTASSSGDAL GKALASIYSP DHSSNNFSPS 350
PSTPVGSPQG LPGTSQWPRA GAPSALSPNY DAGLHGLQSK MEDRLDEAIH 400
VLRSHAVGTA SDLHGLLPGH GALTTSFTGP MSLGGRHAGL VGGSHPEEGL 450
TSGASLLHNH ASLPSQPSSL PDLSQRPPDS YSGLGRAGTT AGASEIKREE 500
KEDEEIASVA DAEEDKKDLK VPRTRTSTDE VLSLEEKDLR DRERRMANNA 550
RERVRVRDIN EAFRELGRMC QLHLKSDKAQ TKLLILQQAV QVILGLEQQV 600
RERNLNPKAA CLKRREEEKV SGVVGDPQLA LSAAHPGLGE AHNPAGHL 648
Length:648
Mass (Da):67,458
Last modified:April 5, 2011 - v1
Checksum:i601A68FD940D7506
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC152062 Genomic DNA. No translation available.
RefSeqiNP_001157625.1. NM_001164153.1.
UniGeneiMm.3406.

Genome annotation databases

EnsembliENSMUST00000105340; ENSMUSP00000100977; ENSMUSG00000020167.
GeneIDi21423.
KEGGimmu:21423.
UCSCiuc007gdl.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC152062 Genomic DNA. No translation available.
RefSeqi NP_001157625.1. NM_001164153.1.
UniGenei Mm.3406.

3D structure databases

ProteinModelPortali E9PWE4.
SMRi E9PWE4. Positions 536-608.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000105340 ; ENSMUSP00000100977 ; ENSMUSG00000020167 .
GeneIDi 21423.
KEGGi mmu:21423.
UCSCi uc007gdl.2. mouse.

Organism-specific databases

CTDi 6929.
MGIi MGI:98510. Tcf3.

Phylogenomic databases

GeneTreei ENSGT00510000046438.
KOi K09063.

Miscellaneous databases

ChiTaRSi TCF3. mouse.
NextBioi 300742.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9PWE4.
Bgeei E9PWE4.

Family and domain databases

Gene3Di 4.10.280.10. 1 hit.
InterProi IPR011598. bHLH_dom.
[Graphical view ]
Pfami PF00010. HLH. 1 hit.
[Graphical view ]
SMARTi SM00353. HLH. 1 hit.
[Graphical view ]
SUPFAMi SSF47459. SSF47459. 1 hit.
PROSITEi PS50888. BHLH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9PWE4_MOUSE
AccessioniPrimary (citable) accession number: E9PWE4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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