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Protein
Submitted name:

Transcription factor E2-alpha

Gene

Tcf3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor E2-alphaImported
Gene namesi
Name:Tcf3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:98510. Tcf3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiE9PWE2.
PeptideAtlasiE9PWE2.

Expressioni

Gene expression databases

BgeeiE9PWE2.
ExpressionAtlasiE9PWE2. baseline and differential.
GenevisibleiE9PWE2. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000100979.

Structurei

3D structure databases

ProteinModelPortaliE9PWE2.
SMRiE9PWE2. Positions 2-38, 549-608.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini548 – 60154BHLH (basic helix-loop-helix)InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG3910. Eukaryota.
ENOG410XYUA. LUCA.
GeneTreeiENSGT00510000046438.
TreeFamiTF321672.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PWE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNQSQRMAP VGSDKELSDL LDFSMMFPLP VANGKSRPAS LGGTQFAGSG
60 70 80 90 100
LEDRPSSGSW GSSDQNSSSF DPSRTYSEGA HFSDSHSSLP PSTFLGAGLG
110 120 130 140 150
GKGSERNAYA TFGRDTSVGT LSQAGFLPGE LSLSSPGPLS PSGIKSSSQY
160 170 180 190 200
YPSFPSNPRR RAADGGLADT QPKKVRKVPP GLPSSVYPPS SGDSYSRDAA
210 220 230 240 250
AYPSAKTPSS AYPSPFYVAD GSLHPSAELW STPSQVGFGP MLGDGSSPLP
260 270 280 290 300
LAPGSSSVGS GTFGGLQQQD RMGYQLHGSE VNGSLPAVSS FSAAPGTYSG
310 320 330 340 350
TSGHTPPVSG AAAESLLGTR GTTASSSGDA LGKALASIYS PDHSSNNFSP
360 370 380 390 400
SPSTPVGSPQ GLPGTSQWPR AGAPSALSPN YDAGLHGLQS KMEDRLDEAI
410 420 430 440 450
HVLRSHAVGT ASDLHGLLPG HGALTTSFTG PMSLGGRHAG LVGGSHPEEG
460 470 480 490 500
LTSGASLLHN HASLPSQPSS LPDLSQRPPD SYSGLGRAGT TAGASEIKRE
510 520 530 540 550
EKEDEEIASV ADAEEDKKDL KVPRTRTSPD EDEDDLLPPE QKAEREKERR
560 570 580 590 600
VANNARERLR VRDINEAFKE LGRMCQLHLS SEKPQTKLLI LHQAVAVILS
610 620 630 640 650
LEQQVRERNL NPKAACLKRR EEEKVSGVVG DPQLALSAAH PGLGEAHNPA

GHL
Length:653
Mass (Da):67,900
Last modified:April 5, 2011 - v1
Checksum:iEAC10EC77D565B36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152062 Genomic DNA. No translation available.
RefSeqiNP_001157619.1. NM_001164147.1.
UniGeneiMm.3406.

Genome annotation databases

EnsembliENSMUST00000105342; ENSMUSP00000100979; ENSMUSG00000020167.
GeneIDi21423.
UCSCiuc007gdf.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152062 Genomic DNA. No translation available.
RefSeqiNP_001157619.1. NM_001164147.1.
UniGeneiMm.3406.

3D structure databases

ProteinModelPortaliE9PWE2.
SMRiE9PWE2. Positions 2-38, 549-608.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000100979.

Proteomic databases

PaxDbiE9PWE2.
PeptideAtlasiE9PWE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000105342; ENSMUSP00000100979; ENSMUSG00000020167.
GeneIDi21423.
UCSCiuc007gdf.2. mouse.

Organism-specific databases

CTDi6929.
MGIiMGI:98510. Tcf3.

Phylogenomic databases

eggNOGiKOG3910. Eukaryota.
ENOG410XYUA. LUCA.
GeneTreeiENSGT00510000046438.
TreeFamiTF321672.

Miscellaneous databases

ChiTaRSiTcf3. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiE9PWE2.
ExpressionAtlasiE9PWE2. baseline and differential.
GenevisibleiE9PWE2. MM.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
[Graphical view]
PfamiPF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9PWE2_MOUSE
AccessioniPrimary (citable) accession number: E9PWE2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 6, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.