E9PVX6 (E9PVX6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein Mki67 Ensembl ENSMUSP00000033310

Gene names

Name:

Mki67 Ensembl ENSMUSP00000033310 MGI 106035

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000033310

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	3177 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000033310

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA metabolic process Inferred from electronic annotation. Source: Compara cell proliferation Inferred from direct assay PubMed 12972605PubMed 19303854. Source: MGI cellular response to heat Inferred from electronic annotation. Source: Compara meiosis Inferred from direct assay PubMed 12355204. Source: MGI organ regeneration Inferred from electronic annotation. Source: Compara
Cellular_component	chromosome, centromeric region Inferred from direct assay PubMed 12355204. Source: MGI condensed chromosome Inferred from direct assay PubMed 12355204. Source: MGI cytoplasm Inferred from direct assay PubMed 11731231. Source: MGI nucleolus Inferred from direct assay PubMed 12355204PubMed 15237214. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PVX6 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 969A3BE300D755B0	FASTA	3,177	350,864
	10 20 30 40 50 60 MASSAHLVTI KRSGDDGAHF PLSLSSCLFG RSIECDIRIQ LPVVSKRHCK IEVKEQEAIL 70 80 90 100 110 120 YNFSSTNPTQ VNGVTIDEPV RLRHGDIITI IDRSFRYEDG NHEDGSKPTE FPGKSLGKEP 130 140 150 160 170 180 SRRASRDSFC ADPDGEGQDT KASKMTASRR SFVYAKGLSA DSPASDGSKN SVSQDSSGHV 190 200 210 220 230 240 EQHTGRNIVE PTSGDLFKKS RSTGSSYREP KSSPTQSLSN SNEKESPFEK LYQSMKEELD 250 260 270 280 290 300 VKSQKSCRKS EPQPDRAAEE SRETQLLVSG RARAKSSGST PVTAASSPKV GKIWTERWRG 310 320 330 340 350 360 GMVPVQTSTE TAKMKTPVRH SQQLKDEDSR VTGRRHSVNL DEGESAQAVH KTVTPGKLAT 370 380 390 400 410 420 RNQAAVEAGD VASPADTPEH SSSKKRSIPA KVEAPSAETQ KRLSLTQRLV PGEKKTPKGS 430 440 450 460 470 480 FSKPEKLATA AEQTCSGLPG LSSVDISNFG DSINKSEGMP MKRRRVSFGG HLRPELFDEN 490 500 510 520 530 540 LPPNTPLKRG ETPTKRKSLG THSPAVLKTI IKERPQSPGK QESPGITPPR TNDQRRRSGR 550 560 570 580 590 600 TSSGSKFLCE TDIPKKAGRK SGNLPAKRAS ISRSQHGILQ MICSKRRSGA SEANLIVAKS 610 620 630 640 650 660 WADVVKLGVK QTQTKVAKHV PQKQTSKRQR RPSTPKKPTS NLHNQFTTGH ANSPCTIVVG 670 680 690 700 710 720 RAQIEKVSVP ARPYKMLNNL MLNRKVDFSE DLSGLTEMFK TPVKEKQQQM SDTGSVLSNS 730 740 750 760 770 780 ANLSERQLQV TNSGDIPEPI TTEILGEKVL SSTRNAAKQQ SDRYSASPTL RRRSIKHENT 790 800 810 820 830 840 VQTPKNVHNI TDLEKKTPVS ETEPLKTASS VSKLRRSREL RHTLVETMNE KTEAVLAENT 850 860 870 880 890 900 TARHLRGTFR EQKVDQQVQD NENAPQRCKE SGELSEGSEK TSARRSSARK QKPTKDLLGS 910 920 930 940 950 960 QMVTQTADYA EELLSQGQGT IQNLEESMHM QNTSISEDQG ITEKKVNIIV YATKEKHSPK 970 980 990 1000 1010 1020 TPGKKAQPLE GPAGLKEHFE TPNPKDKPIT EDRTRVLCKS PQVTTENITT NTKPQTSTSG 1030 1040 1050 1060 1070 1080 KKVDMKEESS ALTKRIHMPG ESRHNPKILK LECEDIKALK QSENEMLTST VNGSKRTLEK 1090 1100 1110 1120 1130 1140 SKKKAQPLED LTCFQELFIS PVPTNIIKKI PSKSPHTQPV RTPASTKRLS KTGLSKVDVR 1150 1160 1170 1180 1190 1200 QEPSTLGKRT KSPGRAPGTP APVQEENDST AFMETPKQKL DFAGNSSGSK RRSRTSKNRS 1210 1220 1230 1240 1250 1260 QPLEDLDGFQ ELFQTPAGAS DSVTVEESAK ISLESSQAEP VKTPASTKRR SKMSLMKVDM 1270 1280 1290 1300 1310 1320 KELSILEKQT QSRGRDAGTP APMQEGNGTT AIMETPKQKL DFTGNSTGHK RRPRTPKIRA 1330 1340 1350 1360 1370 1380 QPLEDLDGFQ ELFQTPAGAN DSVTVEESAK MSLESSQAEP VKTPASTKRL SKTDLSKVDV 1390 1400 1410 1420 1430 1440 REDPSILGKK TKSPGRAPGT PAPVQEENDC TAYMETPKQK LESIENLTGL RKQSRTPKDI 1450 1460 1470 1480 1490 1500 TGFQDSFQIP DHANGPLVVV KTKKMFFNSP QPESAITRKS RERQSRASIS KIDVKEELLE 1510 1520 1530 1540 1550 1560 SEEHLQLGEG VDTFQVSTNK VIRSSRKPAK RKLDSTAGMP NSKRMRCSSK DNTPCLEDLN 1570 1580 1590 1600 1610 1620 GFQELFQMPG YANDSLTTGI STMLARSPQL GPVRTQINKK SLPKIILRKM DVTEEISGLW 1630 1640 1650 1660 1670 1680 KQSLGRVHTT QEQEDNAIKA IMEIPKETLQ TAADGTRLTR QPQTPKEKVQ PLEDHSVFQE 1690 1700 1710 1720 1730 1740 LFQTSRYCSD PLIGNKQTRM SLRSPQPGFV RTPRTSKRLA KTSVGNIAVR EKISPVSLPQ 1750 1760 1770 1780 1790 1800 CATGEVVHIP IGPEDDTENK GVKESTPQTL DSSASRTVSK RQQGAHEERP QFSGDLFHPQ 1810 1820 1830 1840 1850 1860 ELFQTPASGK DPVTVDETTK IALQSPQPGH IINPASMKRQ SNMSLRKDMR EFSILEKQTQ 1870 1880 1890 1900 1910 1920 SRGRDAGTPA PMQEENGTTA IMETPKQKLD FIGNSTGHKR RPRTPKNRAQ PLEDLDGFQE 1930 1940 1950 1960 1970 1980 LFQTPAGASD PVSVEESAKI SLASSQAEPV RTPASTKRRS KTGLSKVDVR QEPSTLGKRM 1990 2000 2010 2020 2030 2040 KSLGRAPGTP APVQEENDST AFMETPKQKL DFTGNSSGHK RRPQTPKIRA QPLEDLDGFQ 2050 2060 2070 2080 2090 2100 ELFQTPAGAN DSVTVEESVK MSLESSQAEP VKTPASTKRL SKTGLSKVDV REDPSILEKK 2110 2120 2130 2140 2150 2160 TKSPGTPAPV QEENDCTAFM ETPKQKLDFT GNSSGHKRRP RTPKIRAQPL EDLDGFQELF 2170 2180 2190 2200 2210 2220 QTPAGASDSV TVEESAKMSL ESSQAKPVKT PASTKRLSKT GLSKVDVRED PSTLGKKTKS 2230 2240 2250 2260 2270 2280 PGRAPGTPAP VQEENDSTAF METPKQKLDF AENSSGSKRR SRTSKNRSQP LEDLDGFQEL 2290 2300 2310 2320 2330 2340 FQTPAGASNP VSVEESAKIS LESSQAEPVR TRASTKRLSK TGLNKMDVRE GHSPLSKSSC 2350 2360 2370 2380 2390 2400 ASQKVMQTLT LGEDHGRETK DGKVLLAQKL EPAIYVTRGK RQQRSCKKRS QSPEDLSGVQ 2410 2420 2430 2440 2450 2460 EVFQTSGHNK DSVTVDNLAK LPSSSPPLEP TDTSVTSRRQ ARTGLRKVHV KNELSGGIMH 2470 2480 2490 2500 2510 2520 PQISGEIVDL PREPEGEGKV IKTRKQSVKR KLDTEVNVPR SKRQRITRAE KTLEDLPGFQ 2530 2540 2550 2560 2570 2580 ELCQAPSLVM DSVIVEKTPK MPDKSPEPVD TTSETQARRR LRRLVVTEEP IPQRKTTRVV 2590 2600 2610 2620 2630 2640 RQTRNTQKEP ISDNQGMEEF KESSVQKQDP SVSLTGRRNQ PRTVKEKTQP LEELTSFQEE 2650 2660 2670 2680 2690 2700 TAKRISSKSP QPEEKETLAG LKRQLRIQLI NDGVKEEPTA QRKQPSRETR NTLKEPVGDS 2710 2720 2730 2740 2750 2760 INVEEVKKST KQKIDPVASV PVSKRPRRVP KEKAQALELA GLKGPIQTLG HTDESASDKG 2770 2780 2790 2800 2810 2820 PTQMPCNSLQ PEQVDSFQSS PRRPRTRRGK VEADEEPSAV RKTVSTSRQT MRSRKVPEIG 2830 2840 2850 2860 2870 2880 NNGTQVSKAS IKQTLDTVAK VTGSRRQLRT HKDGVQPLEV LGDSKEITQI SDHSEKLAHD 2890 2900 2910 2920 2930 2940 TSILKSTQQQ KPDSVKPLRT CRRVLRASKE DPKEVLVDTR DHATLQSKSN PLLSPKRKSA 2950 2960 2970 2980 2990 3000 RDGSIVRTRA LRSLAPKQEA TDEKPVPEKK RAASSKRHVS PEPVKMKHLK IVSNKLESVE 3010 3020 3030 3040 3050 3060 EQVSTVMKTE EMEAKRENPV TPDQNSRYRK KTNVKQPRPK FDASAENVGI KKNEKTMKTA 3070 3080 3090 3100 3110 3120 SQETELQNPD DGAKKSTSRG QVSGKRTCLR SRGTTEMPQP CEAEEKTSKP AAEILIKPQE 3130 3140 3150 3160 3170 EKGVSGESDV RCLRSRKTRV ALDSEPKPRV TRGTKKDAKT LKEDEDIVCT KKLRTRS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000033310.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000033310.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC123047 Genomic DNA. No translation available.
IPI	IPI00124959.
RefSeq	NP_001074586.2. NM_001081117.2.
UniGene	Mm.4078.
3D structure databases
ProteinModelPortal	E9PVX6.
SMR	E9PVX6. Positions 7-99.
ModBase	Search...
PTM databases
PhosphoSite	E9PVX6.
Proteomic databases
PRIDE	E9PVX6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000033310; ENSMUSP00000033310; ENSMUSG00000031004.
GeneID	17345.
KEGG	mmu:17345.
Organism-specific databases
CTD	4288.
MGI	MGI:106035. Mki67.
Phylogenomic databases
GeneTree	ENSGT00530000064425.
OMA	TGLSKVD.
Gene expression databases
ArrayExpress	E9PVX6.
Bgee	E9PVX6.
Family and domain databases
Gene3D	2.60.200.20. 1 hit.
InterPro	IPR000253. FHA_dom. IPR012568. K167R. IPR008984. SMAD_FHA_domain. [Graphical view]
Pfam	PF00498. FHA. 1 hit. PF08065. K167R. 16 hits. [Graphical view]
SMART	SM00240. FHA. 1 hit. [Graphical view]
SUPFAM	SSF49879. SMAD_FHA. 1 hit.
PROSITE	PS50006. FHA_DOMAIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	MKI67. mouse.
NextBio	291926.
SOURCE	Search...

Entry information

Entry name

E9PVX6_MOUSE

Accession

Primary (citable) accession number: E9PVX6

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	April 3, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)