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E9PVX6

- E9PVX6_MOUSE

UniProt

E9PVX6 - E9PVX6_MOUSE

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Protein
Submitted name: Protein Mki67
Gene
Mki67
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. DNA metabolic process Source: Ensembl
  2. cell proliferation Source: MGI
  3. cellular response to heat Source: Ensembl
  4. hyaluronan metabolic process Source: Ensembl
  5. meiotic nuclear division Source: MGI
  6. organ regeneration Source: Ensembl
  7. response to organic cyclic compound Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Mki67Imported
Gene namesi
Name:Mki67Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:106035. Mki67.

Subcellular locationi

GO - Cellular componenti

  1. chromosome, centromeric region Source: MGI
  2. condensed chromosome Source: MGI
  3. cytoplasm Source: MGI
  4. intracellular Source: MGI
  5. nucleolus Source: MGI
  6. nucleus Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9PVX6.
PRIDEiE9PVX6.

PTM databases

PhosphoSiteiE9PVX6.

Expressioni

Gene expression databases

ArrayExpressiE9PVX6.
BgeeiE9PVX6.

Structurei

3D structure databases

ProteinModelPortaliE9PVX6.
SMRiE9PVX6. Positions 7-99.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000064425.
KOiK17582.
OMAiPGKALQT.
OrthoDBiEOG76QFGJ.
TreeFamiTF336000.

Family and domain databases

Gene3Di2.60.200.20. 1 hit.
InterProiIPR000253. FHA_dom.
IPR012568. K167R.
IPR029334. PP1-bd.
IPR008984. SMAD_FHA_domain.
[Graphical view]
PfamiPF00498. FHA. 1 hit.
PF08065. K167R. 16 hits.
PF15276. PP1_bind. 1 hit.
[Graphical view]
SMARTiSM00240. FHA. 1 hit.
[Graphical view]
SUPFAMiSSF49879. SSF49879. 1 hit.
PROSITEiPS50006. FHA_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PVX6-1 [UniParc]FASTAAdd to Basket

« Hide

MASSAHLVTI KRSGDDGAHF PLSLSSCLFG RSIECDIRIQ LPVVSKRHCK     50
IEVKEQEAIL YNFSSTNPTQ VNGVTIDEPV RLRHGDIITI IDRSFRYEDG 100
NHEDGSKPTE FPGKSLGKEP SRRASRDSFC ADPDGEGQDT KASKMTASRR 150
SFVYAKGLSA DSPASDGSKN SVSQDSSGHV EQHTGRNIVE PTSGDLFKKS 200
RSTGSSYREP KSSPTQSLSN SNEKESPFEK LYQSMKEELD VKSQKSCRKS 250
EPQPDRAAEE SRETQLLVSG RARAKSSGST PVTAASSPKV GKIWTERWRG 300
GMVPVQTSTE TAKMKTPVRH SQQLKDEDSR VTGRRHSVNL DEGESAQAVH 350
KTVTPGKLAT RNQAAVEAGD VASPADTPEH SSSKKRSIPA KVEAPSAETQ 400
KRLSLTQRLV PGEKKTPKGS FSKPEKLATA AEQTCSGLPG LSSVDISNFG 450
DSINKSEGMP MKRRRVSFGG HLRPELFDEN LPPNTPLKRG ETPTKRKSLG 500
THSPAVLKTI IKERPQSPGK QESPGITPPR TNDQRRRSGR TSSGSKFLCE 550
TDIPKKAGRK SGNLPAKRAS ISRSQHGILQ MICSKRRSGA SEANLIVAKS 600
WADVVKLGVK QTQTKVAKHV PQKQTSKRQR RPSTPKKPTS NLHNQFTTGH 650
ANSPCTIVVG RAQIEKVSVP ARPYKMLNNL MLNRKVDFSE DLSGLTEMFK 700
TPVKEKQQQM SDTGSVLSNS ANLSERQLQV TNSGDIPEPI TTEILGEKVL 750
SSTRNAAKQQ SDRYSASPTL RRRSIKHENT VQTPKNVHNI TDLEKKTPVS 800
ETEPLKTASS VSKLRRSREL RHTLVETMNE KTEAVLAENT TARHLRGTFR 850
EQKVDQQVQD NENAPQRCKE SGELSEGSEK TSARRSSARK QKPTKDLLGS 900
QMVTQTADYA EELLSQGQGT IQNLEESMHM QNTSISEDQG ITEKKVNIIV 950
YATKEKHSPK TPGKKAQPLE GPAGLKEHFE TPNPKDKPIT EDRTRVLCKS 1000
PQVTTENITT NTKPQTSTSG KKVDMKEESS ALTKRIHMPG ESRHNPKILK 1050
LECEDIKALK QSENEMLTST VNGSKRTLEK SKKKAQPLED LTCFQELFIS 1100
PVPTNIIKKI PSKSPHTQPV RTPASTKRLS KTGLSKVDVR QEPSTLGKRT 1150
KSPGRAPGTP APVQEENDST AFMETPKQKL DFAGNSSGSK RRSRTSKNRS 1200
QPLEDLDGFQ ELFQTPAGAS DSVTVEESAK ISLESSQAEP VKTPASTKRR 1250
SKMSLMKVDM KELSILEKQT QSRGRDAGTP APMQEGNGTT AIMETPKQKL 1300
DFTGNSTGHK RRPRTPKIRA QPLEDLDGFQ ELFQTPAGAN DSVTVEESAK 1350
MSLESSQAEP VKTPASTKRL SKTDLSKVDV REDPSILGKK TKSPGRAPGT 1400
PAPVQEENDC TAYMETPKQK LESIENLTGL RKQSRTPKDI TGFQDSFQIP 1450
DHANGPLVVV KTKKMFFNSP QPESAITRKS RERQSRASIS KIDVKEELLE 1500
SEEHLQLGEG VDTFQVSTNK VIRSSRKPAK RKLDSTAGMP NSKRMRCSSK 1550
DNTPCLEDLN GFQELFQMPG YANDSLTTGI STMLARSPQL GPVRTQINKK 1600
SLPKIILRKM DVTEEISGLW KQSLGRVHTT QEQEDNAIKA IMEIPKETLQ 1650
TAADGTRLTR QPQTPKEKVQ PLEDHSVFQE LFQTSRYCSD PLIGNKQTRM 1700
SLRSPQPGFV RTPRTSKRLA KTSVGNIAVR EKISPVSLPQ CATGEVVHIP 1750
IGPEDDTENK GVKESTPQTL DSSASRTVSK RQQGAHEERP QFSGDLFHPQ 1800
ELFQTPASGK DPVTVDETTK IALQSPQPGH IINPASMKRQ SNMSLRKDMR 1850
EFSILEKQTQ SRGRDAGTPA PMQEENGTTA IMETPKQKLD FIGNSTGHKR 1900
RPRTPKNRAQ PLEDLDGFQE LFQTPAGASD PVSVEESAKI SLASSQAEPV 1950
RTPASTKRRS KTGLSKVDVR QEPSTLGKRM KSLGRAPGTP APVQEENDST 2000
AFMETPKQKL DFTGNSSGHK RRPQTPKIRA QPLEDLDGFQ ELFQTPAGAN 2050
DSVTVEESVK MSLESSQAEP VKTPASTKRL SKTGLSKVDV REDPSILEKK 2100
TKSPGTPAPV QEENDCTAFM ETPKQKLDFT GNSSGHKRRP RTPKIRAQPL 2150
EDLDGFQELF QTPAGASDSV TVEESAKMSL ESSQAKPVKT PASTKRLSKT 2200
GLSKVDVRED PSTLGKKTKS PGRAPGTPAP VQEENDSTAF METPKQKLDF 2250
AENSSGSKRR SRTSKNRSQP LEDLDGFQEL FQTPAGASNP VSVEESAKIS 2300
LESSQAEPVR TRASTKRLSK TGLNKMDVRE GHSPLSKSSC ASQKVMQTLT 2350
LGEDHGRETK DGKVLLAQKL EPAIYVTRGK RQQRSCKKRS QSPEDLSGVQ 2400
EVFQTSGHNK DSVTVDNLAK LPSSSPPLEP TDTSVTSRRQ ARTGLRKVHV 2450
KNELSGGIMH PQISGEIVDL PREPEGEGKV IKTRKQSVKR KLDTEVNVPR 2500
SKRQRITRAE KTLEDLPGFQ ELCQAPSLVM DSVIVEKTPK MPDKSPEPVD 2550
TTSETQARRR LRRLVVTEEP IPQRKTTRVV RQTRNTQKEP ISDNQGMEEF 2600
KESSVQKQDP SVSLTGRRNQ PRTVKEKTQP LEELTSFQEE TAKRISSKSP 2650
QPEEKETLAG LKRQLRIQLI NDGVKEEPTA QRKQPSRETR NTLKEPVGDS 2700
INVEEVKKST KQKIDPVASV PVSKRPRRVP KEKAQALELA GLKGPIQTLG 2750
HTDESASDKG PTQMPCNSLQ PEQVDSFQSS PRRPRTRRGK VEADEEPSAV 2800
RKTVSTSRQT MRSRKVPEIG NNGTQVSKAS IKQTLDTVAK VTGSRRQLRT 2850
HKDGVQPLEV LGDSKEITQI SDHSEKLAHD TSILKSTQQQ KPDSVKPLRT 2900
CRRVLRASKE DPKEVLVDTR DHATLQSKSN PLLSPKRKSA RDGSIVRTRA 2950
LRSLAPKQEA TDEKPVPEKK RAASSKRHVS PEPVKMKHLK IVSNKLESVE 3000
EQVSTVMKTE EMEAKRENPV TPDQNSRYRK KTNVKQPRPK FDASAENVGI 3050
KKNEKTMKTA SQETELQNPD DGAKKSTSRG QVSGKRTCLR SRGTTEMPQP 3100
CEAEEKTSKP AAEILIKPQE EKGVSGESDV RCLRSRKTRV ALDSEPKPRV 3150
TRGTKKDAKT LKEDEDIVCT KKLRTRS 3177
Length:3,177
Mass (Da):350,864
Last modified:April 5, 2011 - v1
Checksum:i969A3BE300D755B0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC123047 Genomic DNA. No translation available.
RefSeqiNP_001074586.2. NM_001081117.2.
UniGeneiMm.4078.

Genome annotation databases

EnsembliENSMUST00000033310; ENSMUSP00000033310; ENSMUSG00000031004.
GeneIDi17345.
KEGGimmu:17345.
UCSCiuc009kem.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC123047 Genomic DNA. No translation available.
RefSeqi NP_001074586.2. NM_001081117.2.
UniGenei Mm.4078.

3D structure databases

ProteinModelPortali E9PVX6.
SMRi E9PVX6. Positions 7-99.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei E9PVX6.

Proteomic databases

MaxQBi E9PVX6.
PRIDEi E9PVX6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000033310 ; ENSMUSP00000033310 ; ENSMUSG00000031004 .
GeneIDi 17345.
KEGGi mmu:17345.
UCSCi uc009kem.2. mouse.

Organism-specific databases

CTDi 4288.
MGIi MGI:106035. Mki67.

Phylogenomic databases

GeneTreei ENSGT00530000064425.
KOi K17582.
OMAi PGKALQT.
OrthoDBi EOG76QFGJ.
TreeFami TF336000.

Miscellaneous databases

ChiTaRSi MKI67. mouse.
NextBioi 291926.
PROi E9PVX6.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9PVX6.
Bgeei E9PVX6.

Family and domain databases

Gene3Di 2.60.200.20. 1 hit.
InterProi IPR000253. FHA_dom.
IPR012568. K167R.
IPR029334. PP1-bd.
IPR008984. SMAD_FHA_domain.
[Graphical view ]
Pfami PF00498. FHA. 1 hit.
PF08065. K167R. 16 hits.
PF15276. PP1_bind. 1 hit.
[Graphical view ]
SMARTi SM00240. FHA. 1 hit.
[Graphical view ]
SUPFAMi SSF49879. SSF49879. 1 hit.
PROSITEi PS50006. FHA_DOMAIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  4. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE9PVX6_MOUSE
AccessioniPrimary (citable) accession number: E9PVX6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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