E9PVJ6 (E9PVJ6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Receptor-type tyrosine-protein phosphatase O Ensembl ENSMUSP00000131764

Gene names

Name:

Ptpro Ensembl ENSMUSP00000131764 MGI 1097152

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000131764

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	405 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Protein tyrosine phosphate + H2O = protein tyrosine + phosphate. SAAS SAAS000242
Sequence similarities	Contains tyrosine-protein phosphatase domain. SAAS SAAS000387
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000131764

Ontologies

Keywords
Molecular function	Hydrolase Protein phosphatase SAAS SAAS000242
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glomerulus development Inferred from electronic annotation. Source: Ensembl monocyte chemotaxis Inferred from electronic annotation. Source: Ensembl negative regulation of glomerular filtration Inferred from electronic annotation. Source: Ensembl
Molecular_function	protein tyrosine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PVJ6 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: FDA781061EB370FF	FASTA	405	46,962
	10 20 30 40 50 60 MVTEVNPNVV VISVLAILST LLIGLLLVTL VILRKKHLQM ARECGAGTFV NFASLEREGK 70 80 90 100 110 120 LPYSWRRSVF ALLTLLPSCL WTDYLLAFYI NPWSKNGLKK RKLTNPVQLD DFDSYIKDMA 130 140 150 160 170 180 KDSDYKFSLQ FEELKLIGLD IPHFAADLPL NRCKNRYTNI LPYDFSRVRL VSMNEEEGAD 190 200 210 220 230 240 YINANYIPGY NSPQEYIATQ GPLPETRNDF WKMVLQQKSH IIVMLTQCNE KRRVKCDHYW 250 260 270 280 290 300 PFTEEPIAYG DITVEMVSEE EEEDWASRHF RINYADEAQD VMHFNYTAWP DHGVPPANAA 310 320 330 340 350 360 ESILQFVFTV RQQAAKSKGP MIIHCSAGVG RTGTFIALDR LLQHIRDHEF VDILGLVSEM 370 380 390 400 RSYRMSMVQT EEQYIFIHQC VQLMWLRKKQ QFCISDVIYE NVSKS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The phagosomal proteome in interferon-gamma-activated macrophages." Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P. Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[2]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000131764.
[3]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000131764.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC093120 Genomic DNA. No translation available. AC144767 Genomic DNA. No translation available. AC163627 Genomic DNA. No translation available.
RefSeq	NP_001157874.1. NM_001164402.1.
UniGene	Mm.186361. Mm.491536.
3D structure databases
ProteinModelPortal	E9PVJ6.
SMR	E9PVJ6. Positions 105-397.
ModBase	Search...
MobiDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000167002; ENSMUSP00000131764; ENSMUSG00000030223.
GeneID	19277.
KEGG	mmu:19277.
UCSC	uc009emx.2. mouse.
Organism-specific databases
CTD	5800.
MGI	MGI:1097152. Ptpro.
Phylogenomic databases
GeneTree	ENSGT00750000117631.
KO	K18035.
Gene expression databases
Bgee	E9PVJ6.
Family and domain databases
Gene3D	3.90.190.10. 1 hit.
InterPro	IPR029021. Prot-tyrosine_phosphatase-like. IPR000387. Tyr/Dual-sp_Pase. IPR016130. Tyr_Pase_AS. IPR000242. Tyr_Pase_rcpt/non-rcpt. [Graphical view]
Pfam	PF00102. Y_phosphatase. 1 hit. [Graphical view]
PRINTS	PR00700. PRTYPHPHTASE.
SMART	SM00194. PTPc. 1 hit. [Graphical view]
SUPFAM	SSF52799. SSF52799. 1 hit.
PROSITE	PS00383. TYR_PHOSPHATASE_1. 1 hit. PS50056. TYR_PHOSPHATASE_2. 1 hit. PS50055. TYR_PHOSPHATASE_PTP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	296184.
SOURCE	Search...

Entry information

Entry name

E9PVJ6_MOUSE

Accession

Primary (citable) accession number: E9PVJ6

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	June 11, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)