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E9PVJ6

- E9PVJ6_MOUSE

UniProt

E9PVJ6 - E9PVJ6_MOUSE

Protein
Submitted name:

Receptor-type tyrosine-protein phosphatase O

Gene

Ptpro

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: InterPro

    GO - Biological processi

    1. glomerulus development Source: Ensembl
    2. monocyte chemotaxis Source: Ensembl
    3. negative regulation of glomerular filtration Source: Ensembl

    Keywords - Molecular functioni

    Hydrolase, Protein phosphataseSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Receptor-type tyrosine-protein phosphatase OImported
    Gene namesi
    Name:PtproImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 6

    Organism-specific databases

    MGIiMGI:1097152. Ptpro.

    Expressioni

    Gene expression databases

    BgeeiE9PVJ6.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PVJ6.
    SMRiE9PVJ6. Positions 105-397.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00750000117631.
    KOiK18035.

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    IPR016130. Tyr_Pase_AS.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view]
    PfamiPF00102. Y_phosphatase. 1 hit.
    [Graphical view]
    PRINTSiPR00700. PRTYPHPHTASE.
    SMARTiSM00194. PTPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52799. SSF52799. 1 hit.
    PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
    PS50056. TYR_PHOSPHATASE_2. 1 hit.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9PVJ6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVTEVNPNVV VISVLAILST LLIGLLLVTL VILRKKHLQM ARECGAGTFV    50
    NFASLEREGK LPYSWRRSVF ALLTLLPSCL WTDYLLAFYI NPWSKNGLKK 100
    RKLTNPVQLD DFDSYIKDMA KDSDYKFSLQ FEELKLIGLD IPHFAADLPL 150
    NRCKNRYTNI LPYDFSRVRL VSMNEEEGAD YINANYIPGY NSPQEYIATQ 200
    GPLPETRNDF WKMVLQQKSH IIVMLTQCNE KRRVKCDHYW PFTEEPIAYG 250
    DITVEMVSEE EEEDWASRHF RINYADEAQD VMHFNYTAWP DHGVPPANAA 300
    ESILQFVFTV RQQAAKSKGP MIIHCSAGVG RTGTFIALDR LLQHIRDHEF 350
    VDILGLVSEM RSYRMSMVQT EEQYIFIHQC VQLMWLRKKQ QFCISDVIYE 400
    NVSKS 405
    Length:405
    Mass (Da):46,962
    Last modified:April 5, 2011 - v1
    Checksum:iFDA781061EB370FF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC093120 Genomic DNA. No translation available.
    AC144767 Genomic DNA. No translation available.
    AC163627 Genomic DNA. No translation available.
    RefSeqiNP_001157874.1. NM_001164402.1.
    UniGeneiMm.186361.
    Mm.491536.

    Genome annotation databases

    EnsembliENSMUST00000167002; ENSMUSP00000131764; ENSMUSG00000030223.
    GeneIDi19277.
    KEGGimmu:19277.
    UCSCiuc009emx.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC093120 Genomic DNA. No translation available.
    AC144767 Genomic DNA. No translation available.
    AC163627 Genomic DNA. No translation available.
    RefSeqi NP_001157874.1. NM_001164402.1.
    UniGenei Mm.186361.
    Mm.491536.

    3D structure databases

    ProteinModelPortali E9PVJ6.
    SMRi E9PVJ6. Positions 105-397.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000167002 ; ENSMUSP00000131764 ; ENSMUSG00000030223 .
    GeneIDi 19277.
    KEGGi mmu:19277.
    UCSCi uc009emx.2. mouse.

    Organism-specific databases

    CTDi 5800.
    MGIi MGI:1097152. Ptpro.

    Phylogenomic databases

    GeneTreei ENSGT00750000117631.
    KOi K18035.

    Miscellaneous databases

    NextBioi 296184.
    SOURCEi Search...

    Gene expression databases

    Bgeei E9PVJ6.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    IPR016130. Tyr_Pase_AS.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view ]
    Pfami PF00102. Y_phosphatase. 1 hit.
    [Graphical view ]
    PRINTSi PR00700. PRTYPHPHTASE.
    SMARTi SM00194. PTPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52799. SSF52799. 1 hit.
    PROSITEi PS00383. TYR_PHOSPHATASE_1. 1 hit.
    PS50056. TYR_PHOSPHATASE_2. 1 hit.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9PVJ6_MOUSE
    AccessioniPrimary (citable) accession number: E9PVJ6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3