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E9PVD4

- E9PVD4_MOUSE

UniProt

E9PVD4 - E9PVD4_MOUSE

Protein
Submitted name:

Protein Akap13

Gene

Akap13

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. cAMP-dependent protein kinase activity Source: InterPro
    2. Rho guanyl-nucleotide exchange factor activity Source: InterPro

    GO - Biological processi

    1. intracellular signal transduction Source: InterPro
    2. regulation of glucocorticoid mediated signaling pathway Source: MGI

    Enzyme and pathway databases

    ReactomeiREACT_204733. G alpha (12/13) signalling events.
    REACT_209641. NRAGE signals death through JNK.
    REACT_210090. Rho GTPase cycle.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Akap13Imported
    Gene namesi
    Name:Akap13Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:2676556. Akap13.

    Expressioni

    Gene expression databases

    ArrayExpressiE9PVD4.
    BgeeiE9PVD4.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PVD4.
    SMRiE9PVD4. Positions 50-103, 232-607.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PH domain.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00660000095401.

    Family and domain databases

    Gene3Di1.20.900.10. 1 hit.
    2.30.29.30. 1 hit.
    InterProiIPR028852. AKAP13.
    IPR000219. DH-domain.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
    [Graphical view]
    PANTHERiPTHR13944:SF4. PTHR13944:SF4. 1 hit.
    PfamiPF00169. PH. 1 hit.
    PF00621. RhoGEF. 1 hit.
    [Graphical view]
    SMARTiSM00109. C1. 1 hit.
    SM00233. PH. 1 hit.
    SM00325. RhoGEF. 1 hit.
    [Graphical view]
    SUPFAMiSSF48065. SSF48065. 1 hit.
    PROSITEiPS50010. DH_2. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    PS00479. ZF_DAG_PE_1. 1 hit.
    PS50081. ZF_DAG_PE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    E9PVD4-1 [UniParc]FASTAAdd to Basket

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    MSVKWGRLPE VPLITVRFTG LKHGQEKEKE KDKIKEKEKD SKEKEKDKKT    50
    LNGHTFSPIP IVGPISCSQC MKPFTNKDAY TCAGCGAFVH KGCRENLASC 100
    AKVKMKQPKG SLQAHDTSSL PTVIMRNKSS QPKERPRSAV LLADEATAAP 150
    MFTNRRSQQS VSLSKSVSIQ NITGVGNDEN MSNTWKFLSH STDSLNKICK 200
    VNESTESLTD EGVGTDMNEG QLMGDFESDS KQLEAESWSR TVDSKFLKQQ 250
    KKDVVKRQEV IYELMQTELH HIRTLKIMSD VYSRGMMTDL LFEQQMVEKL 300
    FPCLDELISI HSQFFQRILE RKKESLVDKS EKNFLIKRIG DVLVSQFSGE 350
    SAERLKKTYG KFCGQHNQSV NYFKDLYTKD KRFQAFVKKK MSSSVVRRLG 400
    IPECILLVTQ RITKYPVLFQ RILQCTKDNE VEQEDLTQSL SLVKDVIGAV 450
    DSKVASYEKK VRLGEIYTKT DSKSIMRMKS GQMFAKEDLR RKKLVRDGSV 500
    FLKSTTGRLK EVQAVLLTDI LVFLQEKDQK YVFASLDHKS TVISLKKLIV 550
    REVAHEEKGL FLISMGVKDP EMVEVHASSR EERNSWIQII QDTINSLNRD 600
    EDEGIPS 607
    Length:607
    Mass (Da):69,190
    Last modified:April 5, 2011 - v1
    Checksum:iA07E3163A4AF2DA9
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei607 – 6071Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC113019 Genomic DNA. No translation available.
    AC158749 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000094307; ENSMUSP00000091865; ENSMUSG00000066406.
    UCSCiuc009hww.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC113019 Genomic DNA. No translation available.
    AC158749 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9PVD4.
    SMRi E9PVD4. Positions 50-103, 232-607.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000094307 ; ENSMUSP00000091865 ; ENSMUSG00000066406 .
    UCSCi uc009hww.2. mouse.

    Organism-specific databases

    MGIi MGI:2676556. Akap13.

    Phylogenomic databases

    GeneTreei ENSGT00660000095401.

    Enzyme and pathway databases

    Reactomei REACT_204733. G alpha (12/13) signalling events.
    REACT_209641. NRAGE signals death through JNK.
    REACT_210090. Rho GTPase cycle.

    Miscellaneous databases

    NextBioi 35553861.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9PVD4.
    Bgeei E9PVD4.

    Family and domain databases

    Gene3Di 1.20.900.10. 1 hit.
    2.30.29.30. 1 hit.
    InterProi IPR028852. AKAP13.
    IPR000219. DH-domain.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
    [Graphical view ]
    PANTHERi PTHR13944:SF4. PTHR13944:SF4. 1 hit.
    Pfami PF00169. PH. 1 hit.
    PF00621. RhoGEF. 1 hit.
    [Graphical view ]
    SMARTi SM00109. C1. 1 hit.
    SM00233. PH. 1 hit.
    SM00325. RhoGEF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48065. SSF48065. 1 hit.
    PROSITEi PS50010. DH_2. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    PS00479. ZF_DAG_PE_1. 1 hit.
    PS50081. ZF_DAG_PE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9PVD4_MOUSE
    AccessioniPrimary (citable) accession number: E9PVD4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3