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E9PVD4

- E9PVD4_MOUSE

UniProt

E9PVD4 - E9PVD4_MOUSE

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Protein
Submitted name:

Protein Akap13

Gene

Akap13

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. cAMP-dependent protein kinase activity Source: InterPro
  2. Rho guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
  2. regulation of glucocorticoid mediated signaling pathway Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_204733. G alpha (12/13) signalling events.
REACT_209641. NRAGE signals death through JNK.
REACT_210090. Rho GTPase cycle.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Akap13Imported
Gene namesi
Name:Akap13Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:2676556. Akap13.

Expressioni

Gene expression databases

BgeeiE9PVD4.
ExpressionAtlasiE9PVD4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PVD4.
SMRiE9PVD4. Positions 50-103, 232-607.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119193.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR028852. AKAP13.
IPR000219. DH-domain.
IPR002219. PE/DAG-bd.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view]
PANTHERiPTHR13944:SF4. PTHR13944:SF4. 1 hit.
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00109. C1. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PVD4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVKWGRLPE VPLITVRFTG LKHGQEKEKE KDKIKEKEKD SKEKEKDKKT
60 70 80 90 100
LNGHTFSPIP IVGPISCSQC MKPFTNKDAY TCAGCGAFVH KGCRENLASC
110 120 130 140 150
AKVKMKQPKG SLQAHDTSSL PTVIMRNKSS QPKERPRSAV LLADEATAAP
160 170 180 190 200
MFTNRRSQQS VSLSKSVSIQ NITGVGNDEN MSNTWKFLSH STDSLNKICK
210 220 230 240 250
VNESTESLTD EGVGTDMNEG QLMGDFESDS KQLEAESWSR TVDSKFLKQQ
260 270 280 290 300
KKDVVKRQEV IYELMQTELH HIRTLKIMSD VYSRGMMTDL LFEQQMVEKL
310 320 330 340 350
FPCLDELISI HSQFFQRILE RKKESLVDKS EKNFLIKRIG DVLVSQFSGE
360 370 380 390 400
SAERLKKTYG KFCGQHNQSV NYFKDLYTKD KRFQAFVKKK MSSSVVRRLG
410 420 430 440 450
IPECILLVTQ RITKYPVLFQ RILQCTKDNE VEQEDLTQSL SLVKDVIGAV
460 470 480 490 500
DSKVASYEKK VRLGEIYTKT DSKSIMRMKS GQMFAKEDLR RKKLVRDGSV
510 520 530 540 550
FLKSTTGRLK EVQAVLLTDI LVFLQEKDQK YVFASLDHKS TVISLKKLIV
560 570 580 590 600
REVAHEEKGL FLISMGVKDP EMVEVHASSR EERNSWIQII QDTINSLNRD

EDEGIPS
Length:607
Mass (Da):69,190
Last modified:April 5, 2011 - v1
Checksum:iA07E3163A4AF2DA9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei607 – 6071Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC113019 Genomic DNA. No translation available.
AC158749 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000094307; ENSMUSP00000091865; ENSMUSG00000066406.
UCSCiuc009hww.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC113019 Genomic DNA. No translation available.
AC158749 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E9PVD4.
SMRi E9PVD4. Positions 50-103, 232-607.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000094307 ; ENSMUSP00000091865 ; ENSMUSG00000066406 .
UCSCi uc009hww.2. mouse.

Organism-specific databases

MGIi MGI:2676556. Akap13.

Phylogenomic databases

GeneTreei ENSGT00760000119193.

Enzyme and pathway databases

Reactomei REACT_204733. G alpha (12/13) signalling events.
REACT_209641. NRAGE signals death through JNK.
REACT_210090. Rho GTPase cycle.

Miscellaneous databases

NextBioi 35553861.
SOURCEi Search...

Gene expression databases

Bgeei E9PVD4.
ExpressionAtlasi E9PVD4. baseline and differential.

Family and domain databases

Gene3Di 1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR028852. AKAP13.
IPR000219. DH-domain.
IPR002219. PE/DAG-bd.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view ]
PANTHERi PTHR13944:SF4. PTHR13944:SF4. 1 hit.
Pfami PF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view ]
SMARTi SM00109. C1. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view ]
SUPFAMi SSF48065. SSF48065. 1 hit.
PROSITEi PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9PVD4_MOUSE
AccessioniPrimary (citable) accession number: E9PVD4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3