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E9PVD4

- E9PVD4_MOUSE

UniProt

E9PVD4 - E9PVD4_MOUSE

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Protein
Submitted name: Protein Akap13
Gene
Akap13
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. Rho guanyl-nucleotide exchange factor activity Source: InterPro
  2. cAMP-dependent protein kinase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
  2. regulation of glucocorticoid mediated signaling pathway Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_204733. G alpha (12/13) signalling events.
REACT_209641. NRAGE signals death through JNK.
REACT_210090. Rho GTPase cycle.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Akap13Imported
Gene namesi
Name:Akap13Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:2676556. Akap13.

Expressioni

Gene expression databases

ArrayExpressiE9PVD4.
BgeeiE9PVD4.

Structurei

3D structure databases

ProteinModelPortaliE9PVD4.
SMRiE9PVD4. Positions 50-103, 232-607.

Family & Domainsi

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00660000095401.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR028852. AKAP13.
IPR000219. DH-domain.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
[Graphical view]
PANTHERiPTHR13944:SF4. PTHR13944:SF4. 1 hit.
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00109. C1. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PVD4-1 [UniParc]FASTAAdd to Basket

« Hide

MSVKWGRLPE VPLITVRFTG LKHGQEKEKE KDKIKEKEKD SKEKEKDKKT    50
LNGHTFSPIP IVGPISCSQC MKPFTNKDAY TCAGCGAFVH KGCRENLASC 100
AKVKMKQPKG SLQAHDTSSL PTVIMRNKSS QPKERPRSAV LLADEATAAP 150
MFTNRRSQQS VSLSKSVSIQ NITGVGNDEN MSNTWKFLSH STDSLNKICK 200
VNESTESLTD EGVGTDMNEG QLMGDFESDS KQLEAESWSR TVDSKFLKQQ 250
KKDVVKRQEV IYELMQTELH HIRTLKIMSD VYSRGMMTDL LFEQQMVEKL 300
FPCLDELISI HSQFFQRILE RKKESLVDKS EKNFLIKRIG DVLVSQFSGE 350
SAERLKKTYG KFCGQHNQSV NYFKDLYTKD KRFQAFVKKK MSSSVVRRLG 400
IPECILLVTQ RITKYPVLFQ RILQCTKDNE VEQEDLTQSL SLVKDVIGAV 450
DSKVASYEKK VRLGEIYTKT DSKSIMRMKS GQMFAKEDLR RKKLVRDGSV 500
FLKSTTGRLK EVQAVLLTDI LVFLQEKDQK YVFASLDHKS TVISLKKLIV 550
REVAHEEKGL FLISMGVKDP EMVEVHASSR EERNSWIQII QDTINSLNRD 600
EDEGIPS 607
Length:607
Mass (Da):69,190
Last modified:April 5, 2011 - v1
Checksum:iA07E3163A4AF2DA9
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei607 – 6071Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC113019 Genomic DNA. No translation available.
AC158749 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000094307; ENSMUSP00000091865; ENSMUSG00000066406.
UCSCiuc009hww.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC113019 Genomic DNA. No translation available.
AC158749 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E9PVD4.
SMRi E9PVD4. Positions 50-103, 232-607.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000094307 ; ENSMUSP00000091865 ; ENSMUSG00000066406 .
UCSCi uc009hww.2. mouse.

Organism-specific databases

MGIi MGI:2676556. Akap13.

Phylogenomic databases

GeneTreei ENSGT00660000095401.

Enzyme and pathway databases

Reactomei REACT_204733. G alpha (12/13) signalling events.
REACT_209641. NRAGE signals death through JNK.
REACT_210090. Rho GTPase cycle.

Miscellaneous databases

NextBioi 35553861.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9PVD4.
Bgeei E9PVD4.

Family and domain databases

Gene3Di 1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR028852. AKAP13.
IPR000219. DH-domain.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
[Graphical view ]
PANTHERi PTHR13944:SF4. PTHR13944:SF4. 1 hit.
Pfami PF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view ]
SMARTi SM00109. C1. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view ]
SUPFAMi SSF48065. SSF48065. 1 hit.
PROSITEi PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9PVD4_MOUSE
AccessioniPrimary (citable) accession number: E9PVD4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 3, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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