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Protein
Submitted name:

Protein Akap13

Gene

Akap13

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • intracellular signal transduction Source: InterPro
  • regulation of glucocorticoid mediated signaling pathway Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_289095. NRAGE signals death through JNK.
REACT_297947. Rho GTPase cycle.
REACT_299052. G alpha (12/13) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Akap13Imported
Gene namesi
Name:Akap13Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:2676556. Akap13.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9PVD4.
ExpressionAtlasiE9PVD4. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129784.

Structurei

3D structure databases

ProteinModelPortaliE9PVD4.
SMRiE9PVD4. Positions 50-103, 232-607.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119193.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR028852. AKAP13.
IPR000219. DH-domain.
IPR002219. PE/DAG-bd.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view]
PANTHERiPTHR13944:SF4. PTHR13944:SF4. 1 hit.
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00109. C1. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PVD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVKWGRLPE VPLITVRFTG LKHGQEKEKE KDKIKEKEKD SKEKEKDKKT
60 70 80 90 100
LNGHTFSPIP IVGPISCSQC MKPFTNKDAY TCAGCGAFVH KGCRENLASC
110 120 130 140 150
AKVKMKQPKG SLQAHDTSSL PTVIMRNKSS QPKERPRSAV LLADEATAAP
160 170 180 190 200
MFTNRRSQQS VSLSKSVSIQ NITGVGNDEN MSNTWKFLSH STDSLNKICK
210 220 230 240 250
VNESTESLTD EGVGTDMNEG QLMGDFESDS KQLEAESWSR TVDSKFLKQQ
260 270 280 290 300
KKDVVKRQEV IYELMQTELH HIRTLKIMSD VYSRGMMTDL LFEQQMVEKL
310 320 330 340 350
FPCLDELISI HSQFFQRILE RKKESLVDKS EKNFLIKRIG DVLVSQFSGE
360 370 380 390 400
SAERLKKTYG KFCGQHNQSV NYFKDLYTKD KRFQAFVKKK MSSSVVRRLG
410 420 430 440 450
IPECILLVTQ RITKYPVLFQ RILQCTKDNE VEQEDLTQSL SLVKDVIGAV
460 470 480 490 500
DSKVASYEKK VRLGEIYTKT DSKSIMRMKS GQMFAKEDLR RKKLVRDGSV
510 520 530 540 550
FLKSTTGRLK EVQAVLLTDI LVFLQEKDQK YVFASLDHKS TVISLKKLIV
560 570 580 590 600
REVAHEEKGL FLISMGVKDP EMVEVHASSR EERNSWIQII QDTINSLNRD

EDEGIPS
Length:607
Mass (Da):69,190
Last modified:April 5, 2011 - v1
Checksum:iA07E3163A4AF2DA9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei607 – 6071Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113019 Genomic DNA. No translation available.
AC158749 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000094307; ENSMUSP00000091865; ENSMUSG00000066406.
UCSCiuc009hww.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113019 Genomic DNA. No translation available.
AC158749 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PVD4.
SMRiE9PVD4. Positions 50-103, 232-607.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129784.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000094307; ENSMUSP00000091865; ENSMUSG00000066406.
UCSCiuc009hww.2. mouse.

Organism-specific databases

MGIiMGI:2676556. Akap13.

Phylogenomic databases

GeneTreeiENSGT00760000119193.

Enzyme and pathway databases

ReactomeiREACT_289095. NRAGE signals death through JNK.
REACT_297947. Rho GTPase cycle.
REACT_299052. G alpha (12/13) signalling events.

Miscellaneous databases

ChiTaRSiAkap13. mouse.
NextBioi35553861.
SOURCEiSearch...

Gene expression databases

BgeeiE9PVD4.
ExpressionAtlasiE9PVD4. baseline and differential.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR028852. AKAP13.
IPR000219. DH-domain.
IPR002219. PE/DAG-bd.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view]
PANTHERiPTHR13944:SF4. PTHR13944:SF4. 1 hit.
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00109. C1. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9PVD4_MOUSE
AccessioniPrimary (citable) accession number: E9PVD4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 24, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.