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E9PV91

- E9PV91_MOUSE

UniProt

E9PV91 - E9PV91_MOUSE

Protein
Submitted name:

A disintegrin and metalloproteinase with thrombospondin motifs 4

Gene

Adamts4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: MGI
    2. metallopeptidase activity Source: MGI
    3. protein binding Source: MGI
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. defense response to bacterium Source: MGI
    2. proteolysis Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    A disintegrin and metalloproteinase with thrombospondin motifs 4Imported
    Gene namesi
    Name:Adamts4Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 1

    Organism-specific databases

    MGIiMGI:1339949. Adamts4.

    Subcellular locationi

    GO - Cellular componenti

    1. proteinaceous extracellular matrix Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiE9PV91.
    BgeeiE9PV91.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PV91.
    SMRiE9PV91. Positions 26-616.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains peptidase M12B domain.SAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00650000092972.

    Family and domain databases

    Gene3Di3.40.390.10. 1 hit.
    InterProiIPR010294. ADAM_spacer1.
    IPR024079. MetalloPept_cat_dom.
    IPR001590. Peptidase_M12B.
    IPR013273. Peptidase_M12B_ADAM-TS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF05986. ADAM_spacer1. 1 hit.
    PF01421. Reprolysin. 1 hit.
    PF00090. TSP_1. 1 hit.
    [Graphical view]
    PRINTSiPR01857. ADAMTSFAMILY.
    SMARTiSM00209. TSP1. 1 hit.
    [Graphical view]
    SUPFAMiSSF82895. SSF82895. 1 hit.
    PROSITEiPS50215. ADAM_MEPRO. 1 hit.
    PS50092. TSP1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9PV91-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKGGERDLRT LLSLIFFLLL LKRFASLSRF VETLVVADDK MAAFHGTGLK    50
    RYLLTVMAAA AKAFKHPSIR NPVNLVVTRL VILGSGQEGP QVGPSAAQTL 100
    RSFCTWQRGL NTPNDSDPDH FDTAILFTRQ DLCGVSTCDT LGMADVGTVC 150
    DPARSCAIVE DDGLQSAFTA AHELGHVFNM LHDNSKPCTN LNGQGGSSRH 200
    VMAPVMAHVD PEEPWSPCSA RFITDFLDNG YGHCLLDKPE APLHLPATFP 250
    GKDYDADRQC QLTFGPDSSH CPQLPPPCAA LWCSGHLNGH AMCQTKHSPW 300
    ADGTPCGSSQ ACMGGRCLHV DQLKDFNVPQ AGGWGPWGPW GDCSRTCGGG 350
    VQFSSRDCTR PVPRNGGKYC EGRRTRFRSC NTENCPHGSA LTFREEQCAA 400
    YNHRTDLFKS FPGPMDWVPR YTGVAPRDQC KLTCQARALG YYYVLEPRVA 450
    DGTPCSPDTS SVCVQGRCIH AGCDRIIGSK KKFDKCMVCG GDGSRCSKQS 500
    GSFKKFRYGY SDVVTIPAGA THILVRQQGG SGLKSIYLAL KLSDGSYALN 550
    GEYTLMPSPT DVVLPGAVSL RYSGATAASE TLSGHGPLAQ PLTLQVLVAG 600
    NPQNARLRYS FFVPRPVPST PRPPPQDWLQ RRAEILKILR KRPWAGRK 648
    Length:648
    Mass (Da):70,429
    Last modified:April 5, 2011 - v1
    Checksum:i15E230E049B59751
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC084821 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000111314; ENSMUSP00000106946; ENSMUSG00000006403.
    UCSCiuc007dno.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC084821 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9PV91.
    SMRi E9PV91. Positions 26-616.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000111314 ; ENSMUSP00000106946 ; ENSMUSG00000006403 .
    UCSCi uc007dno.1. mouse.

    Organism-specific databases

    MGIi MGI:1339949. Adamts4.

    Phylogenomic databases

    GeneTreei ENSGT00650000092972.

    Miscellaneous databases

    NextBioi 35553845.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9PV91.
    Bgeei E9PV91.

    Family and domain databases

    Gene3Di 3.40.390.10. 1 hit.
    InterProi IPR010294. ADAM_spacer1.
    IPR024079. MetalloPept_cat_dom.
    IPR001590. Peptidase_M12B.
    IPR013273. Peptidase_M12B_ADAM-TS.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF05986. ADAM_spacer1. 1 hit.
    PF01421. Reprolysin. 1 hit.
    PF00090. TSP_1. 1 hit.
    [Graphical view ]
    PRINTSi PR01857. ADAMTSFAMILY.
    SMARTi SM00209. TSP1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF82895. SSF82895. 1 hit.
    PROSITEi PS50215. ADAM_MEPRO. 1 hit.
    PS50092. TSP1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9PV91_MOUSE
    AccessioniPrimary (citable) accession number: E9PV91
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3