E9PV91 (E9PV91_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
A disintegrin and metalloproteinase with thrombospondin motifs 4 Ensembl ENSMUSP00000106946

Gene names

Name:

Adamts4 Ensembl ENSMUSP00000106946 MGI 1339949

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000106946

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	648 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 peptidase M12B domain. SAAS SAAS001590
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000106946

Ontologies

Keywords
Molecular function	Hydrolase Protease SAAS SAAS001590
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from direct assay PubMed 15192113. Source: MGI
Cellular_component	proteinaceous extracellular matrix Inferred from electronic annotation. Source: InterPro
Molecular_function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro metallopeptidase activity Inferred from direct assay PubMed 15192113. Source: MGI zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PV91 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 15E230E049B59751	FASTA	648	70,429
	10 20 30 40 50 60 MKGGERDLRT LLSLIFFLLL LKRFASLSRF VETLVVADDK MAAFHGTGLK RYLLTVMAAA 70 80 90 100 110 120 AKAFKHPSIR NPVNLVVTRL VILGSGQEGP QVGPSAAQTL RSFCTWQRGL NTPNDSDPDH 130 140 150 160 170 180 FDTAILFTRQ DLCGVSTCDT LGMADVGTVC DPARSCAIVE DDGLQSAFTA AHELGHVFNM 190 200 210 220 230 240 LHDNSKPCTN LNGQGGSSRH VMAPVMAHVD PEEPWSPCSA RFITDFLDNG YGHCLLDKPE 250 260 270 280 290 300 APLHLPATFP GKDYDADRQC QLTFGPDSSH CPQLPPPCAA LWCSGHLNGH AMCQTKHSPW 310 320 330 340 350 360 ADGTPCGSSQ ACMGGRCLHV DQLKDFNVPQ AGGWGPWGPW GDCSRTCGGG VQFSSRDCTR 370 380 390 400 410 420 PVPRNGGKYC EGRRTRFRSC NTENCPHGSA LTFREEQCAA YNHRTDLFKS FPGPMDWVPR 430 440 450 460 470 480 YTGVAPRDQC KLTCQARALG YYYVLEPRVA DGTPCSPDTS SVCVQGRCIH AGCDRIIGSK 490 500 510 520 530 540 KKFDKCMVCG GDGSRCSKQS GSFKKFRYGY SDVVTIPAGA THILVRQQGG SGLKSIYLAL 550 560 570 580 590 600 KLSDGSYALN GEYTLMPSPT DVVLPGAVSL RYSGATAASE TLSGHGPLAQ PLTLQVLVAG 610 620 630 640 NPQNARLRYS FFVPRPVPST PRPPPQDWLQ RRAEILKILR KRPWAGRK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000106946.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000106946.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC084821 Genomic DNA. No translation available.
IPI	IPI00830958.
3D structure databases
ProteinModelPortal	E9PV91.
SMR	E9PV91. Positions 26-616.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000111314; ENSMUSP00000106946; ENSMUSG00000006403.
UCSC	uc007dno.1. mouse.
Organism-specific databases
MGI	MGI:1339949. Adamts4.
Phylogenomic databases
GeneTree	ENSGT00650000092972.
Gene expression databases
ArrayExpress	E9PV91.
Bgee	E9PV91.
Family and domain databases
Gene3D	3.40.390.10. 1 hit.
InterPro	IPR010294. ADAM_spacer1. IPR024079. MetalloPept_cat_dom. IPR001590. Peptidase_M12B. IPR013273. Peptidase_M12B_ADAM-TS. IPR000884. Thrombospondin_1_rpt. [Graphical view]
Pfam	PF05986. ADAM_spacer1. 1 hit. PF01421. Reprolysin. 1 hit. PF00090. TSP_1. 1 hit. [Graphical view]
PRINTS	PR01857. ADAMTSFAMILY.
SMART	SM00209. TSP1. 1 hit. [Graphical view]
SUPFAM	SSF82895. TSP1. 1 hit.
PROSITE	PS50215. ADAM_MEPRO. 1 hit. PS50092. TSP1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35553845.
SOURCE	Search...

Entry information

Entry name

E9PV91_MOUSE

Accession

Primary (citable) accession number: E9PV91

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 29, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)