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E9PV91

- E9PV91_MOUSE

UniProt

E9PV91 - E9PV91_MOUSE

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Protein
Submitted name: A disintegrin and metalloproteinase with thrombospondin motifs 4
Gene
Adamts4
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. metalloendopeptidase activity Source: MGI
  2. metallopeptidase activity Source: MGI
  3. protein binding Source: MGI
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. defense response to bacterium Source: MGI
  2. proteolysis Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, MetalloproteaseSAAS annotations, Protease

Names & Taxonomyi

Protein namesi
Submitted name:
A disintegrin and metalloproteinase with thrombospondin motifs 4Imported
Gene namesi
Name:Adamts4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 1

Organism-specific databases

MGIiMGI:1339949. Adamts4.

Subcellular locationi

GO - Cellular componenti

  1. proteinaceous extracellular matrix Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiE9PV91.
BgeeiE9PV91.

Structurei

3D structure databases

ProteinModelPortaliE9PV91.
SMRiE9PV91. Positions 26-616.

Family & Domainsi

Sequence similaritiesi

Contains peptidase M12B domain.SAAS annotations

Phylogenomic databases

GeneTreeiENSGT00650000092972.

Family and domain databases

Gene3Di3.40.390.10. 1 hit.
InterProiIPR010294. ADAM_spacer1.
IPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
IPR013273. Peptidase_M12B_ADAM-TS.
IPR000884. Thrombospondin_1_rpt.
[Graphical view]
PfamiPF05986. ADAM_spacer1. 1 hit.
PF01421. Reprolysin. 1 hit.
PF00090. TSP_1. 1 hit.
[Graphical view]
PRINTSiPR01857. ADAMTSFAMILY.
SMARTiSM00209. TSP1. 1 hit.
[Graphical view]
SUPFAMiSSF82895. SSF82895. 1 hit.
PROSITEiPS50215. ADAM_MEPRO. 1 hit.
PS50092. TSP1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PV91-1 [UniParc]FASTAAdd to Basket

« Hide

MKGGERDLRT LLSLIFFLLL LKRFASLSRF VETLVVADDK MAAFHGTGLK    50
RYLLTVMAAA AKAFKHPSIR NPVNLVVTRL VILGSGQEGP QVGPSAAQTL 100
RSFCTWQRGL NTPNDSDPDH FDTAILFTRQ DLCGVSTCDT LGMADVGTVC 150
DPARSCAIVE DDGLQSAFTA AHELGHVFNM LHDNSKPCTN LNGQGGSSRH 200
VMAPVMAHVD PEEPWSPCSA RFITDFLDNG YGHCLLDKPE APLHLPATFP 250
GKDYDADRQC QLTFGPDSSH CPQLPPPCAA LWCSGHLNGH AMCQTKHSPW 300
ADGTPCGSSQ ACMGGRCLHV DQLKDFNVPQ AGGWGPWGPW GDCSRTCGGG 350
VQFSSRDCTR PVPRNGGKYC EGRRTRFRSC NTENCPHGSA LTFREEQCAA 400
YNHRTDLFKS FPGPMDWVPR YTGVAPRDQC KLTCQARALG YYYVLEPRVA 450
DGTPCSPDTS SVCVQGRCIH AGCDRIIGSK KKFDKCMVCG GDGSRCSKQS 500
GSFKKFRYGY SDVVTIPAGA THILVRQQGG SGLKSIYLAL KLSDGSYALN 550
GEYTLMPSPT DVVLPGAVSL RYSGATAASE TLSGHGPLAQ PLTLQVLVAG 600
NPQNARLRYS FFVPRPVPST PRPPPQDWLQ RRAEILKILR KRPWAGRK 648
Length:648
Mass (Da):70,429
Last modified:April 5, 2011 - v1
Checksum:i15E230E049B59751
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC084821 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000111314; ENSMUSP00000106946; ENSMUSG00000006403.
UCSCiuc007dno.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC084821 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E9PV91.
SMRi E9PV91. Positions 26-616.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000111314 ; ENSMUSP00000106946 ; ENSMUSG00000006403 .
UCSCi uc007dno.1. mouse.

Organism-specific databases

MGIi MGI:1339949. Adamts4.

Phylogenomic databases

GeneTreei ENSGT00650000092972.

Miscellaneous databases

NextBioi 35553845.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9PV91.
Bgeei E9PV91.

Family and domain databases

Gene3Di 3.40.390.10. 1 hit.
InterProi IPR010294. ADAM_spacer1.
IPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
IPR013273. Peptidase_M12B_ADAM-TS.
IPR000884. Thrombospondin_1_rpt.
[Graphical view ]
Pfami PF05986. ADAM_spacer1. 1 hit.
PF01421. Reprolysin. 1 hit.
PF00090. TSP_1. 1 hit.
[Graphical view ]
PRINTSi PR01857. ADAMTSFAMILY.
SMARTi SM00209. TSP1. 1 hit.
[Graphical view ]
SUPFAMi SSF82895. SSF82895. 1 hit.
PROSITEi PS50215. ADAM_MEPRO. 1 hit.
PS50092. TSP1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9PV91_MOUSE
AccessioniPrimary (citable) accession number: E9PV91
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi