E9PUR4 (E9PUR4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Laminin subunit alpha-3 Ensembl ENSMUSP00000089703

Gene names

Name:

Lama3 Ensembl ENSMUSP00000089703 MGI 99909

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000089703

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	3330 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000089703

Ontologies

Keywords
Domain	Laminin EGF-like domain SAAS SAAS008211 Repeat SAAS SAAS002049
PTM	Disulfide bond SAAS SAAS008211
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro regulation of cell adhesion Inferred from electronic annotation. Source: InterPro regulation of cell migration Inferred from electronic annotation. Source: InterPro regulation of embryonic development Inferred from electronic annotation. Source: InterPro
Cellular_component	laminin-1 complex Inferred from electronic annotation. Source: InterPro laminin-5 complex Inferred from direct assay PubMed 9264260. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PUR4 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 993EB20BACDD6C59	FASTA	3,330	366,227
	10 20 30 40 50 60 MAVALGRAPR SLPLLLTLLL LLLLRMSPSW SVVGQDHPMS SRSLHPPYFN LAQAARIWAT 70 80 90 100 110 120 ATCGERDPEV SRPRPELFCK LVGGPAAQGS GHTIQGQFCD YCNSEDSRKA HPASHAIDGS 130 140 150 160 170 180 ERWWQSPPLS SGTQYNQVNL TLDLGQLFHV AYILIKFANS PRPDLWILER SVDFGSTYSP 190 200 210 220 230 240 WQYFAHSRRD CVEQFGQEAN MAITQDDQML CVTEYSRIVP LENGEIVVSL INGRPGAKKF 250 260 270 280 290 300 AFSDTLREFT KATNIRLRFL RTNTLLGHLI SKAERDPTVT RRYYYSIKDI SVGGRCVCNG 310 320 330 340 350 360 HAEACSADNP EKQFRCECQH HTCGDTCNRC CAGYNQRRWQ PAGQEQHNEC EACNCHGHAV 370 380 390 400 410 420 DCYYDPDVEH QQASLNSKGV YAGGGVCINC QHNTAGVNCE KCAKGYFRPH GVPVDALHGC 430 440 450 460 470 480 IPCSCDPERA DDCDQGSGHC HCKPNFSGDY CETCADGYYN FPFCLRIPVF PNYTPSPEDP 490 500 510 520 530 540 VAGNIKGCDC NLEGVLPEIC DDRGRCLCRP GVEGPQCDSC RSGSYSFPIC QACQCSTIGS 550 560 570 580 590 600 YPVPCDPGNG QCDCLPGITG RQCDRCLSGA YDFPYCQGSG SVCHPAGTLD SSLGYCQCKQ 610 620 630 640 650 660 HVASPTCSVC KPLYWNLAKE NPRGCSECQC HEAGTLSGIG ECGQEDGDCS CKAHVTGDAC 670 680 690 700 710 720 DTCEDGFFSL EKSNYFGCQG CQCDIGGALT TMCSGPSGVC QCREHVEGKQ CQRPENNYYF 730 740 750 760 770 780 PDLHHMKYEV EDGTGPNGRN LRFGFDPLVF PEFSWRGYAP MTSVQNEVRV RLSVRQSSLS 790 800 810 820 830 840 LFRIVLRYIS PGTEAISGRI TLYSSQGDSD ALQSRKITFP PSKEPAFVTV PGNGFAGPFS 850 860 870 880 890 900 ITPGTWIACI QVEGVLLDYL VLLPRDYYEA FTLQVPVTEP CAHTGSPQDN CLLYQHLPLT 910 920 930 940 950 960 AFSCTLACEA RHFLLDGELR PLAMRQPTPT HPAMVDLSGR EVELQLRLRV PQVGHYVVLL 970 980 990 1000 1010 1020 EYATEVEQLF VVDVNLKSSG SALAGQVNIY SCKYSIPCRS VVIDSLSRTA VHELLADADI 1030 1040 1050 1060 1070 1080 QLKAHMAHFL LYHICIIPAE EFSTEYLRPQ VHCIASYRQH ANPSASCVSL AHETPPTASI 1090 1100 1110 1120 1130 1140 LDATSRGLFS ALPHEPSSPA DGVTLKAPQS QVTLKGLIPH LGRHVFVIHF YQAEHPGFPT 1150 1160 1170 1180 1190 1200 EVIVNGGRQW SGSFLASFCP HLLGCRDQVI SDGQVEFDIS EAEVAVTVKI PDGKSLTLVR 1210 1220 1230 1240 1250 1260 VLVVPAENYD YQILHKTTVD KSSEFISSCG GDSFYIDPQA ASGFCKNSAR SLVAFYHNGA 1270 1280 1290 1300 1310 1320 IPCECDPAGT AGHHCSPEGG QCPCRPNVIG RQCSRCATGY YGFPYCKPCN CGRRLCEEVT 1330 1340 1350 1360 1370 1380 GKCLCPPHTV RPQCEVCEMN SFNFHPVAGC DVCNCSRKGT IEAAVSECDR DSGQCRCKPR 1390 1400 1410 1420 1430 1440 VTGQQCDKCA PGFYQFPECV PCSCNRDGTE PSVCDPETGA CMCKENVEGP QCQLCREGSF 1450 1460 1470 1480 1490 1500 YLDPTNPKGC TKCFCFGVNT DCQSSHKQRA KFVDMMGWRL ETADGVDVPV SFNPGSNSMV 1510 1520 1530 1540 1550 1560 ADLQELPPSV HSASWVAPPS YLGDKVSSYG GYLTYHAKSF GLPGDMVLLG KQPDVQLTGQ 1570 1580 1590 1600 1610 1620 HMSLIHKEPS DPRPDRLHHG RVQVIEGNFR HEGSSAPVSR EELMTVLSRL ERLHIRGLHF 1630 1640 1650 1660 1670 1680 TETQRLTLGE VGLEEASDTG SGPRAHLVEM CACPPDYTGD SCQGCRPGYY WDNKSLPVGR 1690 1700 1710 1720 1730 1740 CVPCNCNGHS NRCQDGSGIC INCQHNTAGE HCERCQAGHY GNAIHGSCRV CPCPHTNSFA 1750 1760 1770 1780 1790 1800 TGCAVDGGAV RCACKPGYTG TQCERCAPGY FGNPQKFGGS CQPCNCNSNG QLGPCDPLTG 1810 1820 1830 1840 1850 1860 DCVNQEPKDG SPAEECDDCD SCVMTLLNDL ASMGEELRLV KSKLQGLSVS TGALEQIRHM 1870 1880 1890 1900 1910 1920 ETQAKDLRNQ LLGFRSATSS HGSKMDDLEK ELSHLNREFE TLQEKAQVNS RKAQTLYNNI 1930 1940 1950 1960 1970 1980 DQTIQSAKEL DMKIKNIVQN VHILLKQMAR PGGEGTDLPV GDWSRELAEA QRMMRDLRSR 1990 2000 2010 2020 2030 2040 DFKKHLQEAE AEKMEAQLLL HRIRTWLESH QVENNGLLKN IRDSLNDYED KLQDLRSILQ 2050 2060 2070 2080 2090 2100 EAAAQAKQAT GINHENEGVL GAIQRQMKEM DSLKNDFTKY LATADSSLLQ TNNLLQQMDK 2110 2120 2130 2140 2150 2160 SQKEYESLAA ALNGARQELS DRVRELSRSG GKAPLVVEAE KHAQSLQELA KQLEEIKRNT 2170 2180 2190 2200 2210 2220 SGDELVRCAV DAATAYENIL NAIRAAEDAA SKATSASKSA FQTVIKEDLP KRAKTLSSDS 2230 2240 2250 2260 2270 2280 EELLNEAKMT QKRLQQVSPA LNSLQQTLKT VSVQKDLLDA NLTVARDDLH GIQRGDIDSV 2290 2300 2310 2320 2330 2340 VIGAKSMVRE ANGITSEVLD GLNPIQTDLG RIKDSYESAR REDFSKALVD ANNSVKKLTR 2350 2360 2370 2380 2390 2400 KLPDLFIKIE SINQQLLPLG NISDNVDRIR ELIQQARDAA NKVAIPMRFN GKSGVEVRLP 2410 2420 2430 2440 2450 2460 NDLEDLKGYT SLSLFLQRPD LRENGGTEDM FVMYLGNKDA SKDYIGMAVV DGQLTCVYNL 2470 2480 2490 2500 2510 2520 GDREAEVQID QVLTESESQE AVMDRVKFQR IYQFAKLNYT KEATSTKPKA PGVYDMESAS 2530 2540 2550 2560 2570 2580 SNTLLNLDPE NAVFYVGGYP PGFELPRRLR FPPYKGCIEL DDLNENVLSL YNFKTTFNLN 2590 2600 2610 2620 2630 2640 TTEVEPCRRR KEESDKNYFE GTGYARIPTQ PNAPFPNFMQ TIQTTVDRGL LFFAENQDNF 2650 2660 2670 2680 2690 2700 ISLNIEDGNL MVKYKLNSEP PKEKGIRDTI NNGRDHMILI SIGKSQKRML INMNKHSIII 2710 2720 2730 2740 2750 2760 EGEIFDFSTY YLGGIPIAIR ERFNISTPAF QGCMKNLKKT SGVVRLNDTV GVTKKCSEDW 2770 2780 2790 2800 2810 2820 KLVRTASFSR GGQMSFTNLD VPSLDRFQLS FGFQTFQPSG TLLNHQTRTS SLLVTLEDGH 2830 2840 2850 2860 2870 2880 IALSTRDSSS PIFKSPGTYM DGLLHHVSVI SDTSGLRLLI DDQVLRRNQR LASFSNAQQS 2890 2900 2910 2920 2930 2940 LSMGGGYFEG CISNVFVQRM SQSPEVLDMA SKSTKRDAFL GGCSLNKPPF LMLFKSPKGF 2950 2960 2970 2980 2990 3000 NKARSFNVNQ LLQDAPQAAR SIEAWQDGKS CLPPLNTKAT HRALQFGDSP TSHLLFKLPQ 3010 3020 3030 3040 3050 3060 ELLKPRLQFS LDIQTTSSRG LVFHTGTRDS FVALYLSEGH VIFALGAGGK KLRLRSKERY 3070 3080 3090 3100 3110 3120 HDGKWHSVVF GLSGRKVHLV VDGLRAQEGS LPGNSTISPR EQVYLGLSPS RKSKSLPQHS 3130 3140 3150 3160 3170 3180 FVGCLRNFQL DSKPLDSPSA RSGVSPCLGG SLEKGIYFSQ GGGHVVLANS VSLEPALTLT 3190 3200 3210 3220 3230 3240 LSIRPRSLTG VLIHIASQSG EHLSVYMEAG KVTTSMNSEA GGTVTSITPK RSLCDGQWHS 3250 3260 3270 3280 3290 3300 VTVSIKQHTL HLELDTDNSY TAGQLSFPPN STRGSLHIGG VPDKLKMLTL PVWNSFFGCL 3310 3320 3330 KNIQVNHIPV PITEATDVQG SVSLNGCPDH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000089703.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000089703.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC102131 Genomic DNA. No translation available. AC102248 Genomic DNA. No translation available. AC139027 Genomic DNA. No translation available. AC157909 Genomic DNA. No translation available.
IPI	IPI01008574.
RefSeq	NP_034810.1. NM_010680.1.
UniGene	Mm.42012.
3D structure databases
ProteinModelPortal	E9PUR4.
SMR	E9PUR4. Positions 43-424.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000092070; ENSMUSP00000089703; ENSMUSG00000024421.
GeneID	16774.
KEGG	mmu:16774.
Organism-specific databases
CTD	3909.
MGI	MGI:99909. Lama3.
Phylogenomic databases
GeneTree	ENSGT00700000104140.
KO	K06240.
OMA	DSCQGCS.
Gene expression databases
Bgee	E9PUR4.
Family and domain databases
Gene3D	2.60.120.200. 5 hits.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR002049. EGF_laminin. IPR018031. Laminin_B_subgr. IPR000034. Laminin_B_type_IV. IPR001791. Laminin_G. IPR009254. Laminin_I. IPR010307. Laminin_II. IPR008211. Laminin_N. [Graphical view]
Pfam	PF00052. Laminin_B. 1 hit. PF00053. Laminin_EGF. 12 hits. PF00054. Laminin_G_1. 1 hit. PF02210. Laminin_G_2. 4 hits. PF06008. Laminin_I. 1 hit. PF06009. Laminin_II. 1 hit. PF00055. Laminin_N. 1 hit. [Graphical view]
SMART	SM00180. EGF_Lam. 13 hits. SM00281. LamB. 1 hit. SM00282. LamG. 5 hits. SM00136. LamNT. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 5 hits.
PROSITE	PS01248. EGF_LAM_1. 12 hits. PS50027. EGF_LAM_2. 13 hits. PS50025. LAM_G_DOMAIN. 5 hits. PS51115. LAMININ_IVA. 1 hit. PS51117. LAMININ_NTER. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	290610.
SOURCE	Search...

Entry information

Entry name

E9PUR4_MOUSE

Accession

Primary (citable) accession number: E9PUR4

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	March 6, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)