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E9PUM0

- E9PUM0_MOUSE

UniProt

E9PUM0 - E9PUM0_MOUSE

Protein
Submitted name:

DNA excision repair protein ERCC-1

Gene

Ercc1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. damaged DNA binding Source: InterPro
    2. endonuclease activity Source: InterPro
    3. protein binding Source: MGI
    4. TBP-class protein binding Source: MGI
    5. TFIID-class transcription factor binding Source: MGI

    GO - Biological processi

    1. cell development Source: MGI
    2. cell proliferation Source: MGI
    3. cellular response to DNA damage stimulus Source: MGI
    4. chromosome organization Source: MGI
    5. DNA recombination Source: MGI
    6. DNA repair Source: MGI
    7. double-strand break repair Source: MGI
    8. germ cell development Source: MGI
    9. interstrand cross-link repair Source: MGI
    10. isotype switching Source: MGI
    11. male gonad development Source: MGI
    12. multicellular organismal aging Source: MGI
    13. multicellular organism growth Source: MGI
    14. nucleotide-excision repair Source: MGI
    15. oogenesis Source: MGI
    16. post-embryonic hemopoiesis Source: MGI
    17. pyrimidine dimer repair by nucleotide-excision repair Source: MGI
    18. replicative cell aging Source: MGI
    19. response to X-ray Source: MGI
    20. spermatogenesis Source: MGI
    21. syncytium formation Source: MGI
    22. UV protection Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    DNA excision repair protein ERCC-1Imported
    Gene namesi
    Name:Ercc1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:95412. Ercc1.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleotide-excision repair complex Source: MGI
    2. transcription factor TFIID complex Source: MGI

    PTM / Processingi

    Proteomic databases

    PRIDEiE9PUM0.

    Expressioni

    Gene expression databases

    ArrayExpressiE9PUM0.
    BgeeiE9PUM0.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PUM0.
    SMRiE9PUM0. Positions 99-227.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000011275.
    KOiK10849.

    Family and domain databases

    InterProiIPR004579. DNA_repair_Rad10.
    IPR011335. Restrct_endonuc-II-like.
    [Graphical view]
    PfamiPF03834. Rad10. 1 hit.
    [Graphical view]
    ProDomiPD013585. DNA_repair_Rad10. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF52980. SSF52980. 1 hit.
    TIGRFAMsiTIGR00597. rad10. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E9PUM0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDPGKDEESR PQPSGPPTRR KFVIPLEEEE VPCAGVKPLF RSSRNPTIPA    50
    TSAHVAPQTY AEYAITQPPG GAGATVPTGS EPAAGENPSQ TLKTGAKSNS 100
    IIVSPRQRGN PVLKFVRNVP WEFGEVIPDY VLGQSTCALF LSLRYHNLHP 150
    DYIHERLQSL GKNFALRVLL VQVDVKDPQQ ALKELAKMCI LADCTLVLAW 200
    SAEEAGRYLE TYKAYEQKPA DLLMEKLEQN FLSRVSLCLL SSCTS 245
    Length:245
    Mass (Da):26,948
    Last modified:April 5, 2011 - v1
    Checksum:i1AA0DD8EED2EE0B2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC148988 Genomic DNA. No translation available.
    RefSeqiNP_001120796.1. NM_001127324.1.
    UniGeneiMm.280913.

    Genome annotation databases

    EnsembliENSMUST00000160369; ENSMUSP00000125655; ENSMUSG00000003549.
    GeneIDi13870.
    KEGGimmu:13870.
    UCSCiuc009fll.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC148988 Genomic DNA. No translation available.
    RefSeqi NP_001120796.1. NM_001127324.1.
    UniGenei Mm.280913.

    3D structure databases

    ProteinModelPortali E9PUM0.
    SMRi E9PUM0. Positions 99-227.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi E9PUM0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000160369 ; ENSMUSP00000125655 ; ENSMUSG00000003549 .
    GeneIDi 13870.
    KEGGi mmu:13870.
    UCSCi uc009fll.2. mouse.

    Organism-specific databases

    CTDi 2067.
    MGIi MGI:95412. Ercc1.

    Phylogenomic databases

    GeneTreei ENSGT00390000011275.
    KOi K10849.

    Miscellaneous databases

    ChiTaRSi ERCC1. mouse.
    NextBioi 284784.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9PUM0.
    Bgeei E9PUM0.

    Family and domain databases

    InterProi IPR004579. DNA_repair_Rad10.
    IPR011335. Restrct_endonuc-II-like.
    [Graphical view ]
    Pfami PF03834. Rad10. 1 hit.
    [Graphical view ]
    ProDomi PD013585. DNA_repair_Rad10. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF52980. SSF52980. 1 hit.
    TIGRFAMsi TIGR00597. rad10. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9PUM0_MOUSE
    AccessioniPrimary (citable) accession number: E9PUM0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3