E9PUM0 (E9PUM0_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA excision repair protein ERCC-1 Ensembl ENSMUSP00000125655

Gene names

Name:

Ercc1 Ensembl ENSMUSP00000125655 MGI 95412

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000125655

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000125655

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	UV protection Inferred from mutant phenotype PubMed 10454634PubMed 16682947PubMed 8275084. Source: MGI cell proliferation Inferred from mutant phenotype PubMed 15692571. Source: MGI chromosome organization Inferred from mutant phenotype PubMed 15199134. Source: MGI double-strand break repair Inferred from mutant phenotype PubMed 15199134PubMed 17912366. Source: MGI germ cell development Inferred from mutant phenotype PubMed 17912366. Source: MGI isotype switching Inferred from mutant phenotype PubMed 15280420. Source: MGI male gonad development Inferred from mutant phenotype PubMed 17912366. Source: MGI multicellular organism growth Inferred from mutant phenotype PubMed 17183314PubMed 22323595. Source: MGI multicellular organismal aging Inferred from mutant phenotype PubMed 17183314. Source: MGI negative regulation of apoptotic process Inferred from mutant phenotype PubMed 17912366. Source: MGI oogenesis Inferred from mutant phenotype PubMed 12466203. Source: MGI post-embryonic hemopoiesis Inferred from mutant phenotype PubMed 15692571. Source: MGI pyrimidine dimer repair by nucleotide-excision repair Inferred from mutant phenotype PubMed 10454634. Source: MGI replicative cell aging Inferred from mutant phenotype PubMed 17173483PubMed 9197240. Source: MGI response to X-ray Inferred from mutant phenotype PubMed 15979950. Source: MGI spermatogenesis Inferred from mutant phenotype PubMed 12466203. Source: MGI syncytium formation Inferred from mutant phenotype PubMed 10834928. Source: MGI
Cellular_component	nucleotide-excision repair complex Inferred from sequence orthology PubMed 3290851. Source: MGI transcription factor TFIID complex Inferred from direct assay PubMed 22323595. Source: MGI
Molecular_function	TFIID-class transcription factor binding Inferred from direct assay PubMed 22323595. Source: MGI damaged DNA binding Inferred from electronic annotation. Source: InterPro endonuclease activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9PUM0 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 1AA0DD8EED2EE0B2	FASTA	245	26,948
	10 20 30 40 50 60 MDPGKDEESR PQPSGPPTRR KFVIPLEEEE VPCAGVKPLF RSSRNPTIPA TSAHVAPQTY 70 80 90 100 110 120 AEYAITQPPG GAGATVPTGS EPAAGENPSQ TLKTGAKSNS IIVSPRQRGN PVLKFVRNVP 130 140 150 160 170 180 WEFGEVIPDY VLGQSTCALF LSLRYHNLHP DYIHERLQSL GKNFALRVLL VQVDVKDPQQ 190 200 210 220 230 240 ALKELAKMCI LADCTLVLAW SAEEAGRYLE TYKAYEQKPA DLLMEKLEQN FLSRVSLCLL SSCTS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000125655.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000125655.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC148988 Genomic DNA. No translation available.
IPI	IPI00895230.
RefSeq	NP_001120796.1. NM_001127324.1.
UniGene	Mm.280913.
3D structure databases
ProteinModelPortal	E9PUM0.
SMR	E9PUM0. Positions 99-227.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000160369; ENSMUSP00000125655; ENSMUSG00000003549.
GeneID	13870.
KEGG	mmu:13870.
Organism-specific databases
CTD	2067.
MGI	MGI:95412. Ercc1.
Phylogenomic databases
GeneTree	ENSGT00390000011275.
KO	K10849.
Gene expression databases
ArrayExpress	E9PUM0.
Bgee	E9PUM0.
Family and domain databases
InterPro	IPR004579. DNA_repair_Rad10. IPR011335. Restrct_endonuc-II-like. [Graphical view]
Pfam	PF03834. Rad10. 1 hit. [Graphical view]
ProDom	PD013585. DNA_repair_Rad10. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF52980. Restrict_endonuc_II-like_core. 1 hit.
TIGRFAMs	TIGR00597. rad10. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	ERCC1. mouse.
NextBio	284784.
SOURCE	Search...

Entry information

Entry name

E9PUM0_MOUSE

Accession

Primary (citable) accession number: E9PUM0

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	April 3, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)