Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Insulin-like growth factor I

Gene

Igf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor IImported
Gene namesi
Name:Igf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:96432 Igf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_500324297833 – 143Sequence analysisAdd BLAST111

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiE9PU89

Expressioni

Gene expression databases

BgeeiENSMUSG00000020053
ExpressionAtlasiE9PU89 baseline and differential
GenevisibleiE9PU89 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9PU89
SMRiE9PU89
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 93IlGFInterPro annotationAdd BLAST59

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IJ2T Eukaryota
ENOG4111MIV LUCA
GeneTreeiENSGT00530000063856

Family and domain databases

InterProiView protein in InterPro
IPR022341 IGF-I
IPR016179 Insulin-like
IPR022350 Insulin-like_growth_factor
IPR036438 Insulin-like_sf
IPR022353 Insulin_CS
IPR022352 Insulin_family
PfamiView protein in Pfam
PF00049 Insulin, 2 hits
PRINTSiPR02002 INSLNLIKEGF
PR02005 INSLNLIKEGF1
PR00276 INSULINFAMLY
SMARTiView protein in SMART
SM00078 IlGF, 1 hit
SUPFAMiSSF56994 SSF56994, 1 hit
PROSITEiView protein in PROSITE
PS00262 INSULIN, 1 hit

Sequencei

Sequence statusi: Complete.

E9PU89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAPAIKIHI MSSSHLFYLA LCLLTFTSST TAGPETLCGA ELVDALQFVC
60 70 80 90 100
GPRGFYFNKP TGYGSSIRRA PQTGIVDECC FRSCDLRRLE MYCAPLKPTK
110 120 130 140
AARSIRAQRH TDMPKTQKSP SLSTNKKTKL QRRRKGSTFE EHK
Length:143
Mass (Da):15,992
Last modified:April 5, 2011 - v1
Checksum:iE3242F4BA7C15440
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125082 Genomic DNA No translation available.
AC139754 Genomic DNA No translation available.
RefSeqiNP_001104744.1, NM_001111274.1
XP_017169300.1, XM_017313811.1
XP_017169301.1, XM_017313812.1
UniGeneiMm.268521

Genome annotation databases

EnsembliENSMUST00000122100; ENSMUSP00000112878; ENSMUSG00000020053
GeneIDi16000
UCSCiuc007gra.2 mouse

Similar proteinsi

Entry informationi

Entry nameiE9PU89_MOUSE
AccessioniPrimary (citable) accession number: E9PU89
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health