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Protein
Submitted name:

T-cell surface glycoprotein CD3 epsilon chain

Gene

CD3E

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
T-cell surface glycoprotein CD3 epsilon chainImported
Gene namesi
Name:CD3EImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000198851.9.
HGNCiHGNC:1674. CD3E.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei121 – 145HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198851.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500324294222 – 201Sequence analysisAdd BLAST180

Proteomic databases

PeptideAtlasiE9PSH8.
PRIDEiE9PSH8.

Expressioni

Gene expression databases

BgeeiENSG00000198851.
ExpressionAtlasiE9PSH8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PSH8.
SMRiE9PSH8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 99IGc2InterPro annotationAdd BLAST66

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IYD1. Eukaryota.
ENOG41123JN. LUCA.
GeneTreeiENSGT00510000048592.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR015484. CD3_esu/gsu/dsu.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003598. Ig_sub2.
IPR003110. Phos_immunorcpt_sig_ITAM.
PANTHERiPTHR10570. PTHR10570. 1 hit.
PfamiView protein in Pfam
PF02189. ITAM. 1 hit.
SMARTiView protein in SMART
SM00408. IGc2. 1 hit.
SM00077. ITAM. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiView protein in PROSITE
PS51055. ITAM_1. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PSH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSGTHWRVL GLCLLSVGVW GQDGNEEMAY KVSISGTTVI LTCPQYPGSE
60 70 80 90 100
ILWQHNDKNI GGDEDDKNIG SDEDHLSLKE FSELEQSGYY VCYPRGSKPE
110 120 130 140 150
DANFYLYLRA RVCENCMEMD VMSVATIVIV DICITGGLLL LVYYWSKNRK
160 170 180 190 200
AKAKPVTRGA GAGGRQRGQN KERPPPVPNP DYEPIRKGQR DLYSGLNQRR

I
Length:201
Mass (Da):22,564
Last modified:April 5, 2011 - v1
Checksum:i446E300CDA13DF09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001582 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000528600; ENSP00000433975; ENSG00000198851.
UCSCiuc058hxi.1. human.

Similar proteinsi

Entry informationi

Entry nameiE9PSH8_HUMAN
AccessioniPrimary (citable) accession number: E9PSH8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: January 31, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported