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E9PS41

- E9PS41_HUMAN

UniProt

E9PS41 - E9PS41_HUMAN

Protein
Submitted name:

WD repeat-containing protein 74

Gene

WDR74

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. blastocyst formation Source: Ensembl
    2. RNA metabolic process Source: Ensembl

    Enzyme and pathway databases

    SignaLinkiE9PS41.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    WD repeat-containing protein 74Imported
    Gene namesi
    Name:WDR74Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:25529. WDR74.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleolus Source: HPA
    2. nucleus Source: HPA

    PTM / Processingi

    Proteomic databases

    MaxQBiE9PS41.

    Expressioni

    Gene expression databases

    ArrayExpressiE9PS41.
    BgeeiE9PS41.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PS41.
    SMRiE9PS41. Positions 42-243.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    InterProiIPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF00400. WD40. 1 hit.
    [Graphical view]
    SMARTiSM00320. WD40. 2 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E9PS41-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLVGCADRTV KHFSTEDGIF QGQRHCPGGE GMFRGLAQAD GTLITCVDSG    50
    ILRVWHDKDK DTSSDPLLEL RVGPGVCRMR QDPAHPHVVA TGGKENALKI 100
    WDLQGSEEPV FRAKNVRNDW LDLRVPIWDQ DIQFLPGSQK LVTCTGYHQV 150
    RVYDPASPQR RPVLETTYGE YPLTAMTLTP GGNSVIVGNT HGQLAEIDLR 200
    QGRLLGCLKG LAGSVRGLQC HPSKPLLASC GLDRVLRIHR IQNPRGLEHK 250
    VYLKSQLNCL LLSGRDNWED EPQEPQEPNK VPLEDTETDE LWASLEAAAK 300
    RKLSGLEQPQ GALQTRRRKK KRPGSTSP 328
    Length:328
    Mass (Da):36,405
    Last modified:April 5, 2011 - v1
    Checksum:i983F683AD7E08FC5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP001160 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000525752; ENSP00000432113; ENSG00000133316.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP001160 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9PS41.
    SMRi E9PS41. Positions 42-243.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    MaxQBi E9PS41.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000525752 ; ENSP00000432113 ; ENSG00000133316 .

    Organism-specific databases

    HGNCi HGNC:25529. WDR74.
    GenAtlasi Search...

    Enzyme and pathway databases

    SignaLinki E9PS41.

    Miscellaneous databases

    ChiTaRSi WDR74. human.
    NextBioi 35504856.

    Gene expression databases

    ArrayExpressi E9PS41.
    Bgeei E9PS41.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    InterProi IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF00400. WD40. 1 hit.
    [Graphical view ]
    SMARTi SM00320. WD40. 2 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PS41_HUMAN
    AccessioniPrimary (citable) accession number: E9PS41
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3