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E9PS41

- E9PS41_HUMAN

UniProt

E9PS41 - E9PS41_HUMAN

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Protein
Submitted name:

WD repeat-containing protein 74

Gene

WDR74

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. blastocyst formation Source: Ensembl
  2. RNA metabolic process Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiE9PS41.

Names & Taxonomyi

Protein namesi
Submitted name:
WD repeat-containing protein 74Imported
Gene namesi
Name:WDR74Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:25529. WDR74.

Subcellular locationi

GO - Cellular componenti

  1. nucleolus Source: HPA
  2. nucleus Source: HPA
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9PS41.

Expressioni

Gene expression databases

BgeeiE9PS41.
ExpressionAtlasiE9PS41. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PS41.
SMRiE9PS41. Positions 42-243.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000015119.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 2 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PS41-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLVGCADRTV KHFSTEDGIF QGQRHCPGGE GMFRGLAQAD GTLITCVDSG
60 70 80 90 100
ILRVWHDKDK DTSSDPLLEL RVGPGVCRMR QDPAHPHVVA TGGKENALKI
110 120 130 140 150
WDLQGSEEPV FRAKNVRNDW LDLRVPIWDQ DIQFLPGSQK LVTCTGYHQV
160 170 180 190 200
RVYDPASPQR RPVLETTYGE YPLTAMTLTP GGNSVIVGNT HGQLAEIDLR
210 220 230 240 250
QGRLLGCLKG LAGSVRGLQC HPSKPLLASC GLDRVLRIHR IQNPRGLEHK
260 270 280 290 300
VYLKSQLNCL LLSGRDNWED EPQEPQEPNK VPLEDTETDE LWASLEAAAK
310 320
RKLSGLEQPQ GALQTRRRKK KRPGSTSP
Length:328
Mass (Da):36,405
Last modified:April 5, 2011 - v1
Checksum:i983F683AD7E08FC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001160 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000525752; ENSP00000432113; ENSG00000133316.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001160 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E9PS41.
SMRi E9PS41. Positions 42-243.
ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi E9PS41.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000525752 ; ENSP00000432113 ; ENSG00000133316 .

Organism-specific databases

HGNCi HGNC:25529. WDR74.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00390000015119.

Enzyme and pathway databases

SignaLinki E9PS41.

Miscellaneous databases

ChiTaRSi WDR74. human.
NextBioi 35504856.

Gene expression databases

Bgeei E9PS41.
ExpressionAtlasi E9PS41. baseline and differential.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF00400. WD40. 1 hit.
[Graphical view ]
SMARTi SM00320. WD40. 2 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PS41_HUMAN
AccessioniPrimary (citable) accession number: E9PS41
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3