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Protein
Submitted name:

Mitogen-activated protein kinase 3

Gene

MAPK3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiE9PRH7.

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase 3Imported
Gene namesi
Name:MAPK3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:6877. MAPK3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000102882.

PTM / Processingi

Proteomic databases

MaxQBiE9PRH7.
PaxDbiE9PRH7.
PeptideAtlasiE9PRH7.
PRIDEiE9PRH7.

Expressioni

Gene expression databases

BgeeiENSG00000102882.
ExpressionAtlasiE9PRH7. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000263025.

Structurei

3D structure databases

ProteinModelPortaliE9PRH7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 93Protein kinaseInterPro annotationAdd BLAST93

Phylogenomic databases

eggNOGiKOG0660. Eukaryota.
ENOG410XNY0. LUCA.
GeneTreeiENSGT00550000074298.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR008349. MAPK_ERK1/2.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01770. ERK1ERK2MAPK.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PRH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSNRPIFPG KHYLDQLNHI LGILGSPSQE DLNCIINMKA RNYLQSLPSK
60 70 80 90 100
TKVAWAKLFP KSDSKALDLL DRMLTFNPNK RITVEEALAH PYLEQYYDPT
110 120 130
DEPVAEEPFT FAMELDDLPK ERLKELIFQE TARFQP
Length:136
Mass (Da):15,764
Last modified:April 5, 2011 - v1
Checksum:i09330B504BF9D082
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei136Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012645 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000478356; ENSP00000432292; ENSG00000102882.
UCSCiuc059tbc.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012645 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PRH7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000263025.

Proteomic databases

MaxQBiE9PRH7.
PaxDbiE9PRH7.
PeptideAtlasiE9PRH7.
PRIDEiE9PRH7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000478356; ENSP00000432292; ENSG00000102882.
UCSCiuc059tbc.1. human.

Organism-specific databases

HGNCiHGNC:6877. MAPK3.
OpenTargetsiENSG00000102882.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0660. Eukaryota.
ENOG410XNY0. LUCA.
GeneTreeiENSGT00550000074298.

Enzyme and pathway databases

SignaLinkiE9PRH7.

Gene expression databases

BgeeiENSG00000102882.
ExpressionAtlasiE9PRH7. baseline and differential.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR008349. MAPK_ERK1/2.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01770. ERK1ERK2MAPK.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9PRH7_HUMAN
AccessioniPrimary (citable) accession number: E9PRH7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 2, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.