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Protein
Submitted name:

Interferon regulatory factor 7

Gene

IRF7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 7Imported
Gene namesi
Name:IRF7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000185507.19
HGNCiHGNC:6122 IRF7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185507

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PQ11
PRIDEiE9PQ11

Expressioni

Gene expression databases

BgeeiENSG00000185507
ExpressionAtlasiE9PQ11 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PQ11
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 135IRF tryptophan pentad repeatInterPro annotationAdd BLAST125

Sequence similaritiesi

Belongs to the IRF family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IWNR Eukaryota
ENOG4111G85 LUCA
GeneTreeiENSGT00760000119093

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001346 Interferon_reg_fact_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR11949 PTHR11949, 1 hit
PfamiView protein in Pfam
PF00605 IRF, 1 hit
PRINTSiPR00267 INTFRNREGFCT
SMARTiView protein in SMART
SM00348 IRF, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS51507 IRF_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PQ11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALAPERAAP RVLFGEWLLG EISSGCYEGL QWLDEARTCF RVPWKHFARK
60 70 80 90 100
DLSEADARIF KVGTPAPPRP GWESPPRTPR ARHTCSVPLF RPGLWPAAGG
110 120 130
RLAAGEVARP PRLRLRSAPA GKPTSAAHCA ARVAS
Length:135
Mass (Da):14,701
Last modified:April 5, 2011 - v1
Checksum:i65FD5B22E9601DB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006284 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000533190; ENSP00000434524; ENSG00000185507
UCSCiuc057xiy.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PQ11_HUMAN
AccessioniPrimary (citable) accession number: E9PQ11
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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Main funding by: National Institutes of Health