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Protein

Tyrosine-protein phosphatase

Gene

PTPRJ

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphataseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine-protein phosphataseUniRule annotation (EC:3.1.3.48UniRule annotation)
Gene namesi
Name:PTPRJImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149177.12.
HGNCiHGNC:9673. PTPRJ.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149177.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 35Sequence analysisAdd BLAST35
ChainiPRO_500324289536 – 120Tyrosine-protein phosphataseSequence analysisAdd BLAST85

Proteomic databases

MaxQBiE9PPH3.
PaxDbiE9PPH3.
PeptideAtlasiE9PPH3.
PRIDEiE9PPH3.

Expressioni

Gene expression databases

BgeeiENSG00000149177.
ExpressionAtlasiE9PPH3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PPH3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 120Fibronectin type-IIIInterPro annotationAdd BLAST79

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0791. Eukaryota.
COG5599. LUCA.
GeneTreeiENSGT00880000137849.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
PfamiView protein in Pfam
PF00041. fn3. 1 hit.
SMARTiView protein in SMART
SM00060. FN3. 1 hit.
SUPFAMiSSF49265. SSF49265. 1 hit.
PROSITEiView protein in PROSITE
PS50853. FN3. 1 hit.

Sequencei

Sequence statusi: Fragment.

E9PPH3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPAAREARL PPRSPGLRWA LPLLLLLLRL GQILCAGGRP SPVFDIKAVS
60 70 80 90 100
ISPTNVILTW KSNDTAASEY KYVVKHKMEN EKTITVVHQP WCNITGLRPA
110 120
TSYVFSITPG IGNETWGDPR
Length:120
Mass (Da):13,292
Last modified:April 5, 2011 - v1
Checksum:i47EB68519BF95A76
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei120Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026975 Genomic DNA. No translation available.
AC103828 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000534219; ENSP00000432686; ENSG00000149177.
UCSCiuc058biq.1. human.

Entry informationi

Entry nameiE9PPH3_HUMAN
AccessioniPrimary (citable) accession number: E9PPH3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 27, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported