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Protein
Submitted name:

ATP-sensitive inward rectifier potassium channel 11

Gene

KCNJ11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transportSAAS annotation, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-sensitive inward rectifier potassium channel 11Imported
Gene namesi
Name:KCNJ11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:6257. KCNJ11.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei57 – 8125HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE9PPF1.

Expressioni

Gene expression databases

BgeeiE9PPF1.
ExpressionAtlasiE9PPF1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000345708.

Chemistry

BindingDBiE9PPF1.

Structurei

3D structure databases

ProteinModelPortaliE9PPF1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3827. Eukaryota.
ENOG410XQ62. LUCA.
GeneTreeiENSGT00760000118842.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR003279. K_chnl_inward-rec_Kir6.2.
IPR013518. K_chnl_inward-rec_Kir_cyto.
[Graphical view]
PANTHERiPTHR11767. PTHR11767. 1 hit.
PTHR11767:SF44. PTHR11767:SF44. 1 hit.
PfamiPF01007. IRK. 1 hit.
[Graphical view]
PRINTSiPR01332. KIR62CHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Fragment.

E9PPF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAWWLIAFAH GDLAPSEGTA EPCVTSIHSF SSAFLFSIEV QVTIGFGGRM
60 70 80 90 100
VTEECPLAIL ILIVQNIVGL MINAIMLGCI FMKTAQAHRR AETLIFSKHA
110 120 130 140 150
VIALRHGRLC FMLRVGDLRK SMIISATIHM QVVRKTTSPE GEVVPLHQVD

IPM
Length:153
Mass (Da):16,856
Last modified:April 5, 2011 - v1
Checksum:iA211B38254113612
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei153 – 1531Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124798 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000526912; ENSP00000432729; ENSG00000187486.
UCSCiuc057zmp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124798 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PPF1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000345708.

Chemistry

BindingDBiE9PPF1.

Proteomic databases

PaxDbiE9PPF1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000526912; ENSP00000432729; ENSG00000187486.
UCSCiuc057zmp.1. human.

Organism-specific databases

HGNCiHGNC:6257. KCNJ11.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3827. Eukaryota.
ENOG410XQ62. LUCA.
GeneTreeiENSGT00760000118842.

Miscellaneous databases

NextBioi35504093.

Gene expression databases

BgeeiE9PPF1.
ExpressionAtlasiE9PPF1. baseline and differential.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR003279. K_chnl_inward-rec_Kir6.2.
IPR013518. K_chnl_inward-rec_Kir_cyto.
[Graphical view]
PANTHERiPTHR11767. PTHR11767. 1 hit.
PTHR11767:SF44. PTHR11767:SF44. 1 hit.
PfamiPF01007. IRK. 1 hit.
[Graphical view]
PRINTSiPR01332. KIR62CHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PPF1_HUMAN
AccessioniPrimary (citable) accession number: E9PPF1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 16, 2016
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.