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E9PPF1

- E9PPF1_HUMAN

UniProt

E9PPF1 - E9PPF1_HUMAN

Protein
Submitted name:

ATP-sensitive inward rectifier potassium channel 11

Gene

KCNJ11

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP-activated inward rectifier potassium channel activity Source: Ensembl
    2. ATP binding Source: Ensembl

    GO - Biological processi

    1. cellular response to glucose stimulus Source: Ensembl
    2. cellular response to nicotine Source: Ensembl
    3. cellular response to tumor necrosis factor Source: Ensembl
    4. positive regulation of cation channel activity Source: Ensembl
    5. potassium ion import Source: Ensembl
    6. response to drug Source: Ensembl
    7. response to estradiol Source: Ensembl
    8. response to ischemia Source: Ensembl
    9. response to testosterone Source: Ensembl

    Keywords - Molecular functioni

    Ion channel, Voltage-gated channelSAAS annotation

    Keywords - Biological processi

    Ion transport, Potassium transportSAAS annotation, Transport

    Keywords - Ligandi

    Potassium

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ATP-sensitive inward rectifier potassium channel 11Imported
    Gene namesi
    Name:KCNJ11Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:6257. KCNJ11.

    Subcellular locationi

    GO - Cellular componenti

    1. ATP-sensitive potassium channel complex Source: Ensembl
    2. axolemma Source: Ensembl
    3. cell body fiber Source: Ensembl
    4. cytosol Source: Ensembl
    5. endoplasmic reticulum Source: Ensembl
    6. endosome Source: Ensembl
    7. intercalated disc Source: Ensembl
    8. mitochondrion Source: Ensembl
    9. myelin sheath Source: Ensembl
    10. neuronal cell body Source: Ensembl
    11. nuclear envelope Source: Ensembl
    12. T-tubule Source: Ensembl

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiE9PPF1.
    BgeeiE9PPF1.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PPF1.
    SMRiE9PPF1. Positions 1-153.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Family and domain databases

    Gene3Di2.60.40.1400. 1 hit.
    InterProiIPR014756. Ig_E-set.
    IPR016449. K_chnl_inward-rec_Kir.
    IPR003279. K_chnl_inward-rec_Kir6.2.
    IPR013518. K_chnl_inward-rec_Kir_cyto.
    [Graphical view]
    PANTHERiPTHR11767. PTHR11767. 1 hit.
    PfamiPF01007. IRK. 1 hit.
    [Graphical view]
    PRINTSiPR01332. KIR62CHANNEL.
    SUPFAMiSSF81296. SSF81296. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    E9PPF1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAWWLIAFAH GDLAPSEGTA EPCVTSIHSF SSAFLFSIEV QVTIGFGGRM    50
    VTEECPLAIL ILIVQNIVGL MINAIMLGCI FMKTAQAHRR AETLIFSKHA 100
    VIALRHGRLC FMLRVGDLRK SMIISATIHM QVVRKTTSPE GEVVPLHQVD 150
    IPM 153
    Length:153
    Mass (Da):16,856
    Last modified:April 5, 2011 - v1
    Checksum:iA211B38254113612
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei153 – 1531Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC124798 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000526912; ENSP00000432729; ENSG00000187486.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC124798 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9PPF1.
    SMRi E9PPF1. Positions 1-153.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000526912 ; ENSP00000432729 ; ENSG00000187486 .

    Organism-specific databases

    HGNCi HGNC:6257. KCNJ11.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi KCNJ11. human.
    NextBioi 35504093.

    Gene expression databases

    ArrayExpressi E9PPF1.
    Bgeei E9PPF1.

    Family and domain databases

    Gene3Di 2.60.40.1400. 1 hit.
    InterProi IPR014756. Ig_E-set.
    IPR016449. K_chnl_inward-rec_Kir.
    IPR003279. K_chnl_inward-rec_Kir6.2.
    IPR013518. K_chnl_inward-rec_Kir_cyto.
    [Graphical view ]
    PANTHERi PTHR11767. PTHR11767. 1 hit.
    Pfami PF01007. IRK. 1 hit.
    [Graphical view ]
    PRINTSi PR01332. KIR62CHANNEL.
    SUPFAMi SSF81296. SSF81296. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PPF1_HUMAN
    AccessioniPrimary (citable) accession number: E9PPF1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3