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E9PPF1

- E9PPF1_HUMAN

UniProt

E9PPF1 - E9PPF1_HUMAN

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Protein
Submitted name:

ATP-sensitive inward rectifier potassium channel 11

Gene

KCNJ11

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP-activated inward rectifier potassium channel activity Source: Ensembl
  2. ATP binding Source: Ensembl

GO - Biological processi

  1. cellular response to glucose stimulus Source: Ensembl
  2. cellular response to nicotine Source: Ensembl
  3. cellular response to tumor necrosis factor Source: Ensembl
  4. positive regulation of cation channel activity Source: Ensembl
  5. potassium ion import Source: Ensembl
  6. response to drug Source: Ensembl
  7. response to estradiol Source: Ensembl
  8. response to ischemia Source: Ensembl
  9. response to testosterone Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transportSAAS annotation, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-sensitive inward rectifier potassium channel 11Imported
Gene namesi
Name:KCNJ11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:6257. KCNJ11.

Subcellular locationi

GO - Cellular componenti

  1. ATP-sensitive potassium channel complex Source: Ensembl
  2. axolemma Source: Ensembl
  3. cell body fiber Source: Ensembl
  4. cytosol Source: Ensembl
  5. endoplasmic reticulum Source: Ensembl
  6. endosome Source: Ensembl
  7. intercalated disc Source: Ensembl
  8. mitochondrion Source: Ensembl
  9. myelin sheath Source: Ensembl
  10. neuronal cell body Source: Ensembl
  11. nuclear envelope Source: Ensembl
  12. T-tubule Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiE9PPF1.
ExpressionAtlasiE9PPF1. baseline.

Structurei

3D structure databases

ProteinModelPortaliE9PPF1.
SMRiE9PPF1. Positions 1-153.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118842.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR003279. K_chnl_inward-rec_Kir6.2.
IPR013518. K_chnl_inward-rec_Kir_cyto.
[Graphical view]
PANTHERiPTHR11767. PTHR11767. 1 hit.
PfamiPF01007. IRK. 1 hit.
[Graphical view]
PRINTSiPR01332. KIR62CHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Fragment.

E9PPF1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAWWLIAFAH GDLAPSEGTA EPCVTSIHSF SSAFLFSIEV QVTIGFGGRM
60 70 80 90 100
VTEECPLAIL ILIVQNIVGL MINAIMLGCI FMKTAQAHRR AETLIFSKHA
110 120 130 140 150
VIALRHGRLC FMLRVGDLRK SMIISATIHM QVVRKTTSPE GEVVPLHQVD

IPM
Length:153
Mass (Da):16,856
Last modified:April 5, 2011 - v1
Checksum:iA211B38254113612
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei153 – 1531Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC124798 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000526912; ENSP00000432729; ENSG00000187486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC124798 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E9PPF1.
SMRi E9PPF1. Positions 1-153.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000526912 ; ENSP00000432729 ; ENSG00000187486 .

Organism-specific databases

HGNCi HGNC:6257. KCNJ11.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118842.

Miscellaneous databases

ChiTaRSi KCNJ11. human.
NextBioi 35504093.

Gene expression databases

Bgeei E9PPF1.
ExpressionAtlasi E9PPF1. baseline.

Family and domain databases

Gene3Di 2.60.40.1400. 1 hit.
InterProi IPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR003279. K_chnl_inward-rec_Kir6.2.
IPR013518. K_chnl_inward-rec_Kir_cyto.
[Graphical view ]
PANTHERi PTHR11767. PTHR11767. 1 hit.
Pfami PF01007. IRK. 1 hit.
[Graphical view ]
PRINTSi PR01332. KIR62CHANNEL.
SUPFAMi SSF81296. SSF81296. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PPF1_HUMAN
AccessioniPrimary (citable) accession number: E9PPF1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3