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E9PPA5

- E9PPA5_HUMAN

UniProt

E9PPA5 - E9PPA5_HUMAN

Protein
Submitted name:

Serine/threonine-protein kinase Chk1

Gene

CHEK1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 2 (14 May 2014)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. protein serine/threonine kinase activity Source: InterPro

    Enzyme and pathway databases

    SignaLinkiE9PPA5.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Serine/threonine-protein kinase Chk1Imported
    Gene namesi
    Name:CHEK1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:1925. CHEK1.

    Expressioni

    Gene expression databases

    ArrayExpressiE9PPA5.
    BgeeiE9PPA5.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PPA5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    E9PPA5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVPFVEDWD LVQTLGEEPD IGMPEPDAQR FFHQLMAGVV YLHGIGITHR    50
    DIKPENLLLD ERDNLKISDF GLATVFRYNN RERLLNKMCG TLPYVAPELL 100
    KRREFHAEPV DVWSCGIVLT AMLAGELPWD QPSDSCQEYS DWKEKKTYLN 150
    PWKKIDSAPL ALLHKILVEN PSARITIPDI KKDRWYNKPL KK 192
    Length:192
    Mass (Da):22,228
    Last modified:May 14, 2014 - v2
    Checksum:iAF03415DCD11B2E9
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei192 – 1921Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP001132 Genomic DNA. No translation available.
    KF455559 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000532669; ENSP00000434646; ENSG00000149554.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP001132 Genomic DNA. No translation available.
    KF455559 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9PPA5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000532669 ; ENSP00000434646 ; ENSG00000149554 .

    Organism-specific databases

    HGNCi HGNC:1925. CHEK1.
    GenAtlasi Search...

    Enzyme and pathway databases

    SignaLinki E9PPA5.

    Miscellaneous databases

    ChiTaRSi CHEK1. human.
    NextBioi 35504054.

    Gene expression databases

    ArrayExpressi E9PPA5.
    Bgeei E9PPA5.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PPA5_HUMAN
    AccessioniPrimary (citable) accession number: E9PPA5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: May 14, 2014
    Last modified: October 1, 2014
    This is version 22 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3