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E9PPA5

- E9PPA5_HUMAN

UniProt

E9PPA5 - E9PPA5_HUMAN

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Protein
Submitted name:

Serine/threonine-protein kinase Chk1

Gene

CHEK1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. protein serine/threonine kinase activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiE9PPA5.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase Chk1Imported
Gene namesi
Name:CHEK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:1925. CHEK1.

Expressioni

Gene expression databases

BgeeiE9PPA5.
ExpressionAtlasiE9PPA5. baseline and differential.

Interactioni

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00730000111032.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PPA5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVPFVEDWD LVQTLGEEPD IGMPEPDAQR FFHQLMAGVV YLHGIGITHR
60 70 80 90 100
DIKPENLLLD ERDNLKISDF GLATVFRYNN RERLLNKMCG TLPYVAPELL
110 120 130 140 150
KRREFHAEPV DVWSCGIVLT AMLAGELPWD QPSDSCQEYS DWKEKKTYLN
160 170 180 190
PWKKIDSAPL ALLHKILVEN PSARITIPDI KKDRWYNKPL KK
Length:192
Mass (Da):22,228
Last modified:May 14, 2014 - v2
Checksum:iAF03415DCD11B2E9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei192 – 1921Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001132 Genomic DNA. No translation available.
KF455559 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000532669; ENSP00000434646; ENSG00000149554.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001132 Genomic DNA. No translation available.
KF455559 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi E9PPA5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000532669 ; ENSP00000434646 ; ENSG00000149554 .

Organism-specific databases

HGNCi HGNC:1925. CHEK1.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00730000111032.

Enzyme and pathway databases

SignaLinki E9PPA5.

Miscellaneous databases

ChiTaRSi CHEK1. human.
NextBioi 35504054.

Gene expression databases

Bgeei E9PPA5.
ExpressionAtlasi E9PPA5. baseline and differential.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PPA5_HUMAN
AccessioniPrimary (citable) accession number: E9PPA5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: May 14, 2014
Last modified: November 26, 2014
This is version 24 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3