Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Serine/threonine-protein kinase Chk1

Gene

CHEK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

SignaLinkiE9PPA5

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase Chk1Imported
Gene namesi
Name:CHEK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149554.12
HGNCiHGNC:1925 CHEK1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149554

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PPA5
PRIDEiE9PPA5

Expressioni

Gene expression databases

BgeeiENSG00000149554
ExpressionAtlasiE9PPA5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PPA5
SMRiE9PPA5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 186Protein kinaseInterPro annotationAdd BLAST186

Phylogenomic databases

eggNOGiKOG0590 Eukaryota
ENOG410XQ0D LUCA
GeneTreeiENSGT00680000099954

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Fragment.

E9PPA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVPFVEDWD LVQTLGEEPD IGMPEPDAQR FFHQLMAGVV YLHGIGITHR
60 70 80 90 100
DIKPENLLLD ERDNLKISDF GLATVFRYNN RERLLNKMCG TLPYVAPELL
110 120 130 140 150
KRREFHAEPV DVWSCGIVLT AMLAGELPWD QPSDSCQEYS DWKEKKTYLN
160 170 180 190
PWKKIDSAPL ALLHKILVEN PSARITIPDI KKDRWYNKPL KK
Length:192
Mass (Da):22,228
Last modified:May 14, 2014 - v2
Checksum:iAF03415DCD11B2E9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei192Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001132 Genomic DNA No translation available.
KF455559 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000532669; ENSP00000434646; ENSG00000149554
UCSCiuc058ivs.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PPA5_HUMAN
AccessioniPrimary (citable) accession number: E9PPA5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: May 14, 2014
Last modified: March 28, 2018
This is version 47 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health