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Protein
Submitted name:

Baculoviral IAP repeat-containing protein 2

Gene

BIRC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

SignaLinkiE9PMH5.

Names & Taxonomyi

Protein namesi
Submitted name:
Baculoviral IAP repeat-containing protein 2Imported
Gene namesi
Name:BIRC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:590. BIRC2.

PTM / Processingi

Proteomic databases

EPDiE9PMH5.
PaxDbiE9PMH5.
PeptideAtlasiE9PMH5.

Expressioni

Gene expression databases

BgeeiE9PMH5.
ExpressionAtlasiE9PMH5. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiE9PMH5. 1 interaction.
STRINGi9606.ENSP00000227758.

Structurei

3D structure databases

ProteinModelPortaliE9PMH5.
SMRiE9PMH5. Positions 20-97, 159-229, 239-595.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini432 – 52291CARDInterPro annotationAdd
BLAST
Domaini550 – 58536RING-typeInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili406 – 43530Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerUniRule annotation

Phylogenomic databases

eggNOGiKOG1101. Eukaryota.
ENOG410YPNM. LUCA.
GeneTreeiENSGT00500000044782.

Family and domain databases

Gene3Di1.10.1170.10. 4 hits.
1.10.533.10. 1 hit.
InterProiIPR001370. BIR_rpt.
IPR028795. C-IAP1.
IPR001315. CARD.
IPR011029. DEATH-like_dom.
IPR001841. Znf_RING.
[Graphical view]
PANTHERiPTHR10044:SF79. PTHR10044:SF79. 1 hit.
PfamiPF00653. BIR. 3 hits.
PF00619. CARD. 1 hit.
[Graphical view]
SMARTiSM00238. BIR. 3 hits.
SM00114. CARD. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS01282. BIR_REPEAT_1. 3 hits.
PS50143. BIR_REPEAT_2. 3 hits.
PS50209. CARD. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PMH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDSTILSDW TNSNKQKMKY DFSCELYRMS TYSTFPAGVP VSERSLARAG
60 70 80 90 100
FYYTGVNDKV KCFCCGLMLD NWKLGDSPIQ KHKQLYPSCS FIQNLVSASL
110 120 130 140 150
GSTSKNTSPM RNSFAHSLSP TLEHSSLFSG SYSSLSPNPL NSRAVEDISS
160 170 180 190 200
SRTNPYSYAM STEEARFLTY HMWPLTFLSP SELARAGFYY IGPGDRVACF
210 220 230 240 250
ACGGKLSNWE PKDDAMSEHR RHFPNCPFLE NSLETLRFSI SNLSMQTHAA
260 270 280 290 300
RMRTFMYWPS SVPVQPEQLA SAGFYYVGRN DDVKCFCCDG GLRCWESGDD
310 320 330 340 350
PWVEHAKWFP RCEFLIRMKG QEFVDEIQGR YPHLLEQLLS TSDTTGEENA
360 370 380 390 400
DPPIIHFGPG ESSSEDAVMM NTPVVKSALE MGFNRDLVKQ TVQSKILTTG
410 420 430 440 450
ENYKTVNDIV SALLNAEDEK REEEKEKQAE EMASDDLSLI RKNRMALFQQ
460 470 480 490 500
LTCVLPILDN LLKANVINKQ EHDIIKQKTQ IPLQARELID TILVKGNAAA
510 520 530 540 550
NIFKNCLKEI DSTLYKNLFV DKNMKYIPTE DVSGLSLEEQ LRRLQEERTC
560 570 580 590
KVCMDKEVSV VFIPCGHLVV CQECAPSLRK CPICRGIIKG TVRTFLS
Length:597
Mass (Da):67,514
Last modified:April 5, 2011 - v1
Checksum:i395B1F4F7045EB80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000942 Genomic DNA. No translation available.
KF455475 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000532672; ENSP00000434979; ENSG00000110330.
UCSCiuc058gve.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000942 Genomic DNA. No translation available.
KF455475 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PMH5.
SMRiE9PMH5. Positions 20-97, 159-229, 239-595.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiE9PMH5. 1 interaction.
STRINGi9606.ENSP00000227758.

Proteomic databases

EPDiE9PMH5.
PaxDbiE9PMH5.
PeptideAtlasiE9PMH5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000532672; ENSP00000434979; ENSG00000110330.
UCSCiuc058gve.1. human.

Organism-specific databases

HGNCiHGNC:590. BIRC2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1101. Eukaryota.
ENOG410YPNM. LUCA.
GeneTreeiENSGT00500000044782.

Enzyme and pathway databases

SignaLinkiE9PMH5.

Miscellaneous databases

ChiTaRSiBIRC2. human.

Gene expression databases

BgeeiE9PMH5.
ExpressionAtlasiE9PMH5. baseline and differential.

Family and domain databases

Gene3Di1.10.1170.10. 4 hits.
1.10.533.10. 1 hit.
InterProiIPR001370. BIR_rpt.
IPR028795. C-IAP1.
IPR001315. CARD.
IPR011029. DEATH-like_dom.
IPR001841. Znf_RING.
[Graphical view]
PANTHERiPTHR10044:SF79. PTHR10044:SF79. 1 hit.
PfamiPF00653. BIR. 3 hits.
PF00619. CARD. 1 hit.
[Graphical view]
SMARTiSM00238. BIR. 3 hits.
SM00114. CARD. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS01282. BIR_REPEAT_1. 3 hits.
PS50143. BIR_REPEAT_2. 3 hits.
PS50209. CARD. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PMH5_HUMAN
AccessioniPrimary (citable) accession number: E9PMH5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 6, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.