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Protein
Submitted name:

Baculoviral IAP repeat-containing protein 2

Gene

BIRC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLinkiE9PMH5

Names & Taxonomyi

Protein namesi
Submitted name:
Baculoviral IAP repeat-containing protein 2Imported
Gene namesi
Name:BIRC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000110330.8
HGNCiHGNC:590 BIRC2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000110330

PTM / Processingi

Proteomic databases

EPDiE9PMH5
MaxQBiE9PMH5
PeptideAtlasiE9PMH5
PRIDEiE9PMH5

Expressioni

Gene expression databases

BgeeiENSG00000110330
ExpressionAtlasiE9PMH5 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiE9PMH5, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliE9PMH5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini432 – 522CARDInterPro annotationAdd BLAST91
Domaini550 – 585RING-typeInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili406 – 435Sequence analysisAdd BLAST30

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1101 Eukaryota
ENOG410YPNM LUCA
GeneTreeiENSGT00500000044782

Family and domain databases

CDDicd00022 BIR, 3 hits
InterProiView protein in InterPro
IPR001370 BIR_rpt
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
IPR001841 Znf_RING
PfamiView protein in Pfam
PF00653 BIR, 3 hits
PF00619 CARD, 1 hit
SMARTiView protein in SMART
SM00238 BIR, 3 hits
SM00114 CARD, 1 hit
SM00184 RING, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS01282 BIR_REPEAT_1, 3 hits
PS50143 BIR_REPEAT_2, 3 hits
PS50209 CARD, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PMH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDSTILSDW TNSNKQKMKY DFSCELYRMS TYSTFPAGVP VSERSLARAG
60 70 80 90 100
FYYTGVNDKV KCFCCGLMLD NWKLGDSPIQ KHKQLYPSCS FIQNLVSASL
110 120 130 140 150
GSTSKNTSPM RNSFAHSLSP TLEHSSLFSG SYSSLSPNPL NSRAVEDISS
160 170 180 190 200
SRTNPYSYAM STEEARFLTY HMWPLTFLSP SELARAGFYY IGPGDRVACF
210 220 230 240 250
ACGGKLSNWE PKDDAMSEHR RHFPNCPFLE NSLETLRFSI SNLSMQTHAA
260 270 280 290 300
RMRTFMYWPS SVPVQPEQLA SAGFYYVGRN DDVKCFCCDG GLRCWESGDD
310 320 330 340 350
PWVEHAKWFP RCEFLIRMKG QEFVDEIQGR YPHLLEQLLS TSDTTGEENA
360 370 380 390 400
DPPIIHFGPG ESSSEDAVMM NTPVVKSALE MGFNRDLVKQ TVQSKILTTG
410 420 430 440 450
ENYKTVNDIV SALLNAEDEK REEEKEKQAE EMASDDLSLI RKNRMALFQQ
460 470 480 490 500
LTCVLPILDN LLKANVINKQ EHDIIKQKTQ IPLQARELID TILVKGNAAA
510 520 530 540 550
NIFKNCLKEI DSTLYKNLFV DKNMKYIPTE DVSGLSLEEQ LRRLQEERTC
560 570 580 590
KVCMDKEVSV VFIPCGHLVV CQECAPSLRK CPICRGIIKG TVRTFLS
Length:597
Mass (Da):67,514
Last modified:April 5, 2011 - v1
Checksum:i395B1F4F7045EB80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000942 Genomic DNA No translation available.
KF455475 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000532672; ENSP00000434979; ENSG00000110330
UCSCiuc058gve.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PMH5_HUMAN
AccessioniPrimary (citable) accession number: E9PMH5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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