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Protein
Submitted name:

RalBP1-associated Eps domain-containing protein 1

Gene

REPS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi331 – 342PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
RalBP1-associated Eps domain-containing protein 1Imported
Gene namesi
Name:REPS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000135597.18
HGNCiHGNC:15578 REPS1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000135597

PTM / Processingi

Proteomic databases

EPDiE9PMG1
MaxQBiE9PMG1
PeptideAtlasiE9PMG1
PRIDEiE9PMG1

Expressioni

Gene expression databases

BgeeiENSG00000135597
ExpressionAtlasiE9PMG1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PMG1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 113EHInterPro annotationAdd BLAST104
Domaini285 – 369EHInterPro annotationAdd BLAST85
Domaini318 – 353EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili696 – 727Sequence analysisAdd BLAST32

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118985

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR000261 EH_dom
IPR026814 Reps1
PANTHERiPTHR11216:SF63 PTHR11216:SF63, 2 hits
PfamiView protein in Pfam
PF12763 EF-hand_4, 1 hit
SMARTiView protein in SMART
SM00027 EH, 2 hits
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit
PS50031 EH, 2 hits

Sequencei

Sequence statusi: Complete.

E9PMG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGLTLSDAE QKYYSDLFSY CDIESTKKVV VNGRVLELFR AAQLPNDVVL
60 70 80 90 100
QIMELCGATR LGYFGRSQFY IALKLVAVAQ SGFPLRVESI NTVKDLPLPR
110 120 130 140 150
FVASKNEQES RHAASYSSDS ENQGSYSGVI PPPPGRGQVK KGSVSHDTVQ
160 170 180 190 200
PRTSADAQEP ASPVVSPQQS PPTSPHTWRK HSRHPSGGNS ERPLAGPGPF
210 220 230 240 250
WSPFGEAQSG SSAGDAVWSG HSPPPPQENW VSFADTPPTS TLLTMHPASV
260 270 280 290 300
QDQTTVRTVA SATTAIEIRR QSSSYDDPWK ITDEQRQYYV NQFKTIQPDL
310 320 330 340 350
NGFIPGSAAK EFFTKSKLPI LELSHIWELS DFDKDGALTL DEFCAAFHLV
360 370 380 390 400
VARKNGYDLP EKLPESLMPK LIDLEDSADV GDQPGEVGYS GSPAEAPPSK
410 420 430 440 450
SPSMPSLNQT WPELNQSSED TAIVHPVPIR MTPSKIHMQE MELKRTGSDH
460 470 480 490 500
TNPTSPLLVK PSDLLEENKI NSSVKFASGN TVADGYSSSD SFTSDPEQIG
510 520 530 540 550
SNVTRQRSHS GTSPDNTAPP PPPPRPQPSH SRSSSLDMNR TFTVTTGQQQ
560 570 580 590 600
AGVVAHPPAV PPRPQPSQAP GPAVHRPVDA DGLITHTSTS PQQIPEQPNF
610 620 630 640 650
ADFSQFEVFA ASNVNDEQDD EAEKHPEVLP SKGTTPLAPP PKPVRRRLKS
660 670 680 690 700
EDELRPEVDE HTQKTGVLAA VLASQPSIPR SVGKDKKAIQ ASIRRNKETN
710 720 730
TVLARLNSEL QQQLKDVLEE RISLEVQLEQ LRPFSHL
Length:737
Mass (Da):80,436
Last modified:April 5, 2011 - v1
Checksum:iD0FE80718F210F3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121834 Genomic DNA No translation available.
AL590308 Genomic DNA No translation available.
AL591033 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000415951; ENSP00000397941; ENSG00000135597
UCSCiuc063rvw.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PMG1_HUMAN
AccessioniPrimary (citable) accession number: E9PMG1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported