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Protein
Submitted name:

RalBP1-associated Eps domain-containing protein 1

Gene

REPS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
RalBP1-associated Eps domain-containing protein 1Imported
Gene namesi
Name:REPS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:15578. REPS1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000135597.

PTM / Processingi

Proteomic databases

MaxQBiE9PMG1.
PeptideAtlasiE9PMG1.
PRIDEiE9PMG1.

Expressioni

Gene expression databases

BgeeiENSG00000135597.
ExpressionAtlasiE9PMG1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PMG1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 113EHInterPro annotationAdd BLAST104
Domaini285 – 369EHInterPro annotationAdd BLAST85
Domaini318 – 353EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili696 – 727Sequence analysisAdd BLAST32

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118985.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EH_dom.
[Graphical view]
PfamiPF12763. EF-hand_4. 1 hit.
[Graphical view]
SMARTiSM00027. EH. 2 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 2 hits.
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.
PS50031. EH. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PMG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGLTLSDAE QKYYSDLFSY CDIESTKKVV VNGRVLELFR AAQLPNDVVL
60 70 80 90 100
QIMELCGATR LGYFGRSQFY IALKLVAVAQ SGFPLRVESI NTVKDLPLPR
110 120 130 140 150
FVASKNEQES RHAASYSSDS ENQGSYSGVI PPPPGRGQVK KGSVSHDTVQ
160 170 180 190 200
PRTSADAQEP ASPVVSPQQS PPTSPHTWRK HSRHPSGGNS ERPLAGPGPF
210 220 230 240 250
WSPFGEAQSG SSAGDAVWSG HSPPPPQENW VSFADTPPTS TLLTMHPASV
260 270 280 290 300
QDQTTVRTVA SATTAIEIRR QSSSYDDPWK ITDEQRQYYV NQFKTIQPDL
310 320 330 340 350
NGFIPGSAAK EFFTKSKLPI LELSHIWELS DFDKDGALTL DEFCAAFHLV
360 370 380 390 400
VARKNGYDLP EKLPESLMPK LIDLEDSADV GDQPGEVGYS GSPAEAPPSK
410 420 430 440 450
SPSMPSLNQT WPELNQSSED TAIVHPVPIR MTPSKIHMQE MELKRTGSDH
460 470 480 490 500
TNPTSPLLVK PSDLLEENKI NSSVKFASGN TVADGYSSSD SFTSDPEQIG
510 520 530 540 550
SNVTRQRSHS GTSPDNTAPP PPPPRPQPSH SRSSSLDMNR TFTVTTGQQQ
560 570 580 590 600
AGVVAHPPAV PPRPQPSQAP GPAVHRPVDA DGLITHTSTS PQQIPEQPNF
610 620 630 640 650
ADFSQFEVFA ASNVNDEQDD EAEKHPEVLP SKGTTPLAPP PKPVRRRLKS
660 670 680 690 700
EDELRPEVDE HTQKTGVLAA VLASQPSIPR SVGKDKKAIQ ASIRRNKETN
710 720 730
TVLARLNSEL QQQLKDVLEE RISLEVQLEQ LRPFSHL
Length:737
Mass (Da):80,436
Last modified:April 5, 2011 - v1
Checksum:iD0FE80718F210F3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121834 Genomic DNA. No translation available.
AL590308 Genomic DNA. No translation available.
AL591033 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000415951; ENSP00000397941; ENSG00000135597.
UCSCiuc063rvw.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121834 Genomic DNA. No translation available.
AL590308 Genomic DNA. No translation available.
AL591033 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PMG1.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9PMG1.
PeptideAtlasiE9PMG1.
PRIDEiE9PMG1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000415951; ENSP00000397941; ENSG00000135597.
UCSCiuc063rvw.1. human.

Organism-specific databases

HGNCiHGNC:15578. REPS1.
OpenTargetsiENSG00000135597.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118985.

Miscellaneous databases

ChiTaRSiREPS1. human.

Gene expression databases

BgeeiENSG00000135597.
ExpressionAtlasiE9PMG1. baseline and differential.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EH_dom.
[Graphical view]
PfamiPF12763. EF-hand_4. 1 hit.
[Graphical view]
SMARTiSM00027. EH. 2 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 2 hits.
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.
PS50031. EH. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9PMG1_HUMAN
AccessioniPrimary (citable) accession number: E9PMG1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 30, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.