E9PMF8 (E9PMF8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Receptor-type tyrosine-protein phosphatase C Ensembl ENSP00000458662

Gene names

Name:

PTPRC Ensembl ENSP00000458662

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000458662

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	733 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000458662

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	T cell receptor signaling pathway Inferred from electronic annotation. Source: InterPro peptidyl-tyrosine dephosphorylation Inferred from electronic annotation. Source: GOC
Molecular_function	protein tyrosine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	733	1	Ensembl ENSP00000458662

Sequences

	Sequence		Length	Mass (Da)
	E9PMF8 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 038140F73BF4F57C	FASTA	733	82,749
	10 20 30 40 50 60 MYLWLKLLAF GFAFLDTEVF VTGQSPTPSP TGVSSVQTPH LPTHADSQTP SAGTDTQTFS 70 80 90 100 110 120 GSAANAKLNP TPGSNAISDV PGERSTASTF PTDPVSPLTT TLSLAHHSSA ALPARTSNTT 130 140 150 160 170 180 ITANTSDAYL NASETTTLSP SGSAVISTTT IATTPSKPTC DEKYANITVD YLYNKETKLF 190 200 210 220 230 240 TAKLNVNENV ECGNNTCTNN EVHNLTECKN ASVSISHNSC TAPDKTLILD VPPGVEKFQL 250 260 270 280 290 300 HDCTQVEKAD TTICLKWKNI ETFTCDTQNI TYRFQCGNMI FDNKEIKLEN LEPEHEYKCD 310 320 330 340 350 360 SEILYNNHKF TNASKIIKTD FGSPGEPQII FCRSEAAHQG VITWNPPQRS FHNFTLCYIK 370 380 390 400 410 420 ETEKDCLNLD KNLIKYDLQN LKPYTKYVLS LHAYIIAKVQ RNGSAAMCHF TTKSAPPSQV 430 440 450 460 470 480 WNMTVSMTSD NSMHVKCRPP RDRNGPHERY HLEVEAGNTL VRNESHKNCD FRVKDLQYST 490 500 510 520 530 540 DYTFKAYFHN GDYPGEPFIL HHSTSYNSKA LIAFLAFLII VTSIALLVVL YKIYDLHKKR 550 560 570 580 590 600 SCNLDEQQEL VERDDEKQLM NVEPIHADIL LETYKRKIAD EGRLFLAEFQ SIPRVFSKFP 610 620 630 640 650 660 IKEARKPFNQ NKNRYVDILP YDYNRVELSE INGDAGSNYI NASYIDGFKE PRKYIAAQGP 670 680 690 700 710 720 RDETVDDFWR MIWEQKATVI VMVTRCEEGN RNKCAEYWPS MEEGTRAFGD VVVKINQHKR 730 CPDYIIQKLN IVN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (MAY-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL157402 Genomic DNA. No translation available.
3D structure databases
SMR	E9PMF8. Positions 323-497, 556-733.
ModBase	Search...
Proteomic databases
PRIDE	E9PMF8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000576833; ENSP00000458662; ENSG00000262418.
Organism-specific databases
HGNC	HGNC:9666. PTPRC.
GenAtlas	Search...
Gene expression databases
ArrayExpress	E9PMF8.
Family and domain databases
Gene3D	2.60.40.10. 2 hits.
InterPro	IPR003961. Fibronectin_type3. IPR013783. Ig-like_fold. IPR016335. Leukocyte_common_ag. IPR024739. PTP_recept_N. IPR000242. Tyr_Pase_rcpt/non-rcpt. [Graphical view]
Pfam	PF12567. CD45. 1 hit. PF00041. fn3. 2 hits. PF12453. PTP_N. 1 hit. PF00102. Y_phosphatase. 1 hit. [Graphical view]
PRINTS	PR00700. PRTYPHPHTASE.
SMART	SM00060. FN3. 2 hits. SM00194. PTPc. 1 hit. [Graphical view]
SUPFAM	SSF49265. FN_III-like. 2 hits.
PROSITE	PS50853. FN3. 2 hits. PS50055. TYR_PHOSPHATASE_PTP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	PTPRC. human.
NextBio	35503518.

Entry information

Entry name

E9PMF8_HUMAN

Accession

Primary (citable) accession number: E9PMF8

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.