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Protein
Submitted name:

Apoptosis-inducing factor 1, mitochondrial

Gene

AIFM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Apoptosis-inducing factor 1, mitochondrialImported
Gene namesi
Name:AIFM1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000156709.13.
HGNCiHGNC:8768. AIFM1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000156709.

PTM / Processingi

Proteomic databases

MaxQBiE9PMA0.
PaxDbiE9PMA0.
PeptideAtlasiE9PMA0.
PRIDEiE9PMA0.

Expressioni

Gene expression databases

BgeeiENSG00000156709.
ExpressionAtlasiE9PMA0. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9PMA0.
SMRiE9PMA0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 121FAD/NAD-binding_domInterPro annotationAdd BLAST117
Domaini126 – 255AIF_CInterPro annotationAdd BLAST130

Phylogenomic databases

eggNOGiKOG1346. Eukaryota.
COG0446. LUCA.
GeneTreeiENSGT00530000063416.

Family and domain databases

Gene3Di3.30.390.30. 1 hit.
3.50.50.60. 1 hit.
InterProiView protein in InterPro
IPR029324. AIF_C.
IPR023753. FAD/NAD-binding_dom.
IPR016156. FAD/NAD-linked_Rdtase_dimer.
PfamiView protein in Pfam
PF14721. AIF_C. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
SUPFAMiSSF51905. SSF51905. 1 hit.
SSF55424. SSF55424. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PMA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKILPEYLS NWTMEKVRRE GVKVMPNAIV QSVGVSSGKL LIKLKDGRKV
60 70 80 90 100
ETDHIVAAVG LEPNVELAKT GGLEIDSDFG GFRVNAELQA RSNIWVAGDA
110 120 130 140 150
ACFYDIKLGR RRVEHHDHAV VSGRLAGENM TGAAKPYWHQ SMFWSDLGPD
160 170 180 190 200
VGYEAIGLVD SSLPTVGVFA KATAQDNPKS ATEQSGTGIR SESETESEAS
210 220 230 240 250
EITIPPSTPA VPQAPVQGED YGKGVIFYLR DKVVVGIVLW NIFNRMPIAR
260 270
KIIKDGEQHE DLNEVAKLFN IHED
Length:274
Mass (Da):29,938
Last modified:April 5, 2011 - v1
Checksum:i0BFD7337C48478BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139234 Genomic DNA. No translation available.
KF459397 Genomic DNA. No translation available.
KF510638 Genomic DNA. No translation available.
RefSeqiNP_001124318.2. NM_001130846.3.
UniGeneiHs.424932.

Genome annotation databases

EnsembliENST00000460436; ENSP00000431222; ENSG00000156709.
GeneIDi9131.
UCSCiuc011mur.3. human.

Similar proteinsi

Entry informationi

Entry nameiE9PMA0_HUMAN
AccessioniPrimary (citable) accession number: E9PMA0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 27, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported