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Protein
Submitted name:

Mitogen-activated protein kinase kinase kinase 11

Gene

MAP3K11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. JUN kinase kinase kinase activity Source: Ensembl

GO - Biological processi

  1. cell death Source: Ensembl
  2. positive regulation of neuron apoptotic process Source: Ensembl
  3. protein autophosphorylation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase kinase kinase 11Imported
Gene namesi
Name:MAP3K11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:6850. MAP3K11.

Expressioni

Gene expression databases

BgeeiE9PLB1.
ExpressionAtlasiE9PLB1. baseline and differential.

Interactioni

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118807.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PLB1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEHKTLKITD FGLAREWHKT TQMSAAGTYA WMAPEVIKAS TFSKGSDVWS
60 70 80 90
FGVLLWELLT GEVPYRGIDC LAVAYGVAVN KLTLPIPSTC PEPFAQ
Length:96
Mass (Da):10,577
Last modified:February 4, 2015 - v4
Checksum:iDEC5624DBD2C3684
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei96 – 961Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001362 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000529839; ENSP00000435237; ENSG00000173327.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001362 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiE9PLB1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000529839; ENSP00000435237; ENSG00000173327.

Organism-specific databases

HGNCiHGNC:6850. MAP3K11.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118807.

Miscellaneous databases

NextBioi35503163.

Gene expression databases

BgeeiE9PLB1.
ExpressionAtlasiE9PLB1. baseline and differential.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamiPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PLB1_HUMAN
AccessioniPrimary (citable) accession number: E9PLB1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: February 4, 2015
Last modified: February 4, 2015
This is version 29 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.