ID   E9PL57_HUMAN            Unreviewed;       170 AA.
AC   E9PL57;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000431482.1};
DE   Flags: Fragment;
GN   Name=NEDD8-MDP1 {ECO:0000313|Ensembl:ENSP00000431482.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000431482.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000431482.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H.,
RA   Du H., Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T.,
RA   Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B.,
RA   Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D.,
RA   Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R.,
RA   Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S.,
RA   Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C.,
RA   Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S.,
RA   Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C.,
RA   Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P.,
RA   Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J.,
RA   Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F.,
RA   Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F.,
RA   Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000431482.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AL096870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; E9PL57; -.
DR   SMR; E9PL57; -.
DR   IntAct; E9PL57; 5.
DR   STRING; 9606.ENSP00000431482; -.
DR   BioMuta; NEDD8-MDP1; -.
DR   EPD; E9PL57; -.
DR   MassIVE; E9PL57; -.
DR   MaxQB; E9PL57; -.
DR   PaxDb; 9606-ENSP00000431482; -.
DR   PeptideAtlas; E9PL57; -.
DR   Ensembl; ENST00000534348.5; ENSP00000431482.1; ENSG00000255526.6.
DR   UCSC; uc059ace.1; human.
DR   AGR; HGNC:39551; -.
DR   GeneCards; NEDD8-MDP1; -.
DR   HGNC; HGNC:39551; NEDD8-MDP1.
DR   VEuPathDB; HostDB:ENSG00000255526; -.
DR   eggNOG; KOG0005; Eukaryota.
DR   eggNOG; KOG4549; Eukaryota.
DR   HOGENOM; CLU_071162_3_2_1; -.
DR   PhylomeDB; E9PL57; -.
DR   TreeFam; TF328413; -.
DR   ChiTaRS; NEDD8-MDP1; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   RNAct; E9PL57; Protein.
DR   Bgee; ENSG00000255526; Expressed in male germ line stem cell (sensu Vertebrata) in testis and 97 other cell types or tissues.
DR   ExpressionAtlas; E9PL57; baseline and differential.
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   CDD; cd07501; HAD_MDP-1_like; 1.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR035679; MDP-1_euk.
DR   InterPro; IPR010036; MDP_1_eu_arc.
DR   InterPro; IPR000626; Ubiquitin-like_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR019956; Ubiquitin_dom.
DR   NCBIfam; TIGR01685; MDP-1; 1.
DR   PANTHER; PTHR17901:SF14; MAGNESIUM-DEPENDENT PHOSPHATASE 1; 1.
DR   PANTHER; PTHR17901; MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1; 1.
DR   Pfam; PF12689; Acid_PPase; 1.
DR   Pfam; PF00240; ubiquitin; 1.
DR   PRINTS; PR00348; UBIQUITIN.
DR   SMART; SM00213; UBQ; 1.
DR   SUPFAM; SSF56784; HAD-like; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          1..51
FT                   /note="Ubiquitin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50053"
FT   NON_TER         170
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000431482.1"
SQ   SEQUENCE   170 AA;  19536 MW;  4FA8A795F05587A7 CRC64;
     MLIKVKTLTG KEIEIDIEPT DKVERIKERV EEKEGIPPQQ QRLIYSGKQI DGTVRDRRGQ
     DVRLYPEVPE VLKRLQSLGV PGAAASRTSE IEGANQLLEL FDLFRYFVHR EIYPGSKITH
     FERLQQKTGI PFSQMIFFDD ERRNIVDVSK LGVTCIHIQN GMNLQTLSQG
//