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Protein

Matrix metalloproteinase

Gene

MMP3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Ca2+UniRule annotation
  • Zn2+UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotation, Protease
LigandCalciumUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Matrix metalloproteinaseUniRule annotation (EC:3.4.24.-UniRule annotation)
Gene namesi
Name:MMP3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149968.11
HGNCiHGNC:7173 MMP3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149968

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17UniRule annotationAdd BLAST17
ChainiPRO_501075562018 – 42Matrix metalloproteinaseUniRule annotationAdd BLAST25

Keywords - PTMi

ZymogenUniRule annotation

Expressioni

Gene expression databases

BgeeiENSG00000149968
ExpressionAtlasiE9PKX2 baseline and differential

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M10A family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG1565 Eukaryota
ENOG410XQ5D LUCA
GeneTreeiENSGT00760000118870

Sequencei

Sequence statusi: Complete.

E9PKX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MKSLPILLLL CVAVCSAYPL DGAAREISRK LLRPQKRCET VC
Length:42
Mass (Da):4,660
Last modified:April 5, 2011 - v1
Checksum:i07E256D194DC0566
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000789 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000524478; ENSP00000435255; ENSG00000149968
UCSCiuc058gwf.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PKX2_HUMAN
AccessioniPrimary (citable) accession number: E9PKX2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported