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Protein

Matrix metalloproteinase

Gene

MMP3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Ca2+UniRule annotation
  • Zn2+UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, MetalloproteaseUniRule annotation, Protease
LigandCalciumUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Matrix metalloproteinaseUniRule annotation (EC:3.4.24.-UniRule annotation)
Gene namesi
Name:MMP3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149968.11.
HGNCiHGNC:7173. MMP3.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149968.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17UniRule annotationAdd BLAST17
ChainiPRO_501075562018 – 42Matrix metalloproteinaseUniRule annotationAdd BLAST25

Keywords - PTMi

ZymogenUniRule annotation

Proteomic databases

PaxDbiE9PKX2.

Expressioni

Gene expression databases

BgeeiENSG00000149968.
ExpressionAtlasiE9PKX2. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M10A family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG1565. Eukaryota.
ENOG410XQ5D. LUCA.
GeneTreeiENSGT00760000118870.

Sequencei

Sequence statusi: Complete.

E9PKX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MKSLPILLLL CVAVCSAYPL DGAAREISRK LLRPQKRCET VC
Length:42
Mass (Da):4,660
Last modified:April 5, 2011 - v1
Checksum:i07E256D194DC0566
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000789 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000524478; ENSP00000435255; ENSG00000149968.
UCSCiuc058gwf.1. human.

Entry informationi

Entry nameiE9PKX2_HUMAN
AccessioniPrimary (citable) accession number: E9PKX2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 27, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported