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Protein
Submitted name:

Neutral alpha-glucosidase AB

Gene

GANAB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Names & Taxonomyi

Protein namesi
Submitted name:
Neutral alpha-glucosidase ABImported
Gene namesi
Name:GANABImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000089597.16
HGNCiHGNC:4138 GANAB

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000089597

PTM / Processingi

Proteomic databases

EPDiE9PKU7
MaxQBiE9PKU7
PeptideAtlasiE9PKU7
PRIDEiE9PKU7

Expressioni

Gene expression databases

BgeeiENSG00000089597
ExpressionAtlasiE9PKU7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PKU7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini162 – 232Gal_mutarotas_2InterPro annotationAdd BLAST71

Sequence similaritiesi

Belongs to the glycosyl hydrolase 31 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1066 Eukaryota
COG1501 LUCA
GeneTreeiENSGT00760000119229

Family and domain databases

Gene3Di2.60.40.1180, 2 hits
InterProiView protein in InterPro
IPR011013 Gal_mutarotase_sf_dom
IPR000322 Glyco_hydro_31
IPR030458 Glyco_hydro_31_AS
IPR030459 Glyco_hydro_31_CS
IPR025887 Glyco_hydro_31_N_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF13802 Gal_mutarotas_2, 1 hit
PF01055 Glyco_hydro_31, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF74650 SSF74650, 1 hit
PROSITEiView protein in PROSITE
PS00129 GLYCOSYL_HYDROL_F31_1, 1 hit
PS00707 GLYCOSYL_HYDROL_F31_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PKU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVAAVAAR RRRLSVSGRD ENSVELTMAE GPYKIILTAR PFRLDLLEDR
60 70 80 90 100
SLLLSVNARG LLEFEHQRAP RVSFSDKVNL TLGSIWDKIK NLFSRQGSKD
110 120 130 140 150
PAEGDGAQPE ETPRDGDKPE ETQGKAEKDE PGAWEETFKT HSDSKPYGPM
160 170 180 190 200
SVGLDFSLPG MEHVYGIPEH ADNLRLKVTE GGEPYRLYNL DVFQYELYNP
210 220 230 240 250
MALYGSVPVL LAHNPHRDLG IFWLNAAETW VDISSNTAGK TLFGKMMDYL
260 270 280 290 300
QGSGETPQTD VRWMSETGII DVFLLLGPSI SDVFRQYASL TGTQALPPLF
310 320 330 340 350
SLGYHQSRWN YRDEADVLEV DQGFDDHNLP CDVIWLDIEH ADGKRYFTWD
360 370 380 390 400
PSRFPQPRTM LERLASKRRK LVAIVDPHIK VDSGYRVHEE LRNLGLYVKT
410 420 430 440 450
RDGSDYEGWC WPGSAGYPDF TNPTMRAWWA NMFSYDNYEG SAPNLFVWND
460 470 480 490 500
MNEPSVFNGP EVTMLKDAQH YGGWEHRDVH NIYGLYVHMA TADGLRQRSG
510 520 530 540 550
GMERPFVLAR AFFAGSQRFG AVWTGDNTAE WDHLKISIPM CLSLGLVGLS
560 570 580 590 600
FCGADVGGFF KNPEPELLVR WYQMGAYQPF FRAHAHLDTG RREPWLLPSQ
610 620 630 640 650
HNDIIRDALG QRYSLLPFWY TLLYQAHREG IPVMRPLWVQ YPQDVTTFNI
660 670 680 690 700
DDQYLLGDAL LVHPVSDSGA HGVQVYLPGQ GEVWYDIQSY QKHHGPQTLY
710 720 730 740 750
LPVTLSSIPV FQRGGTIVPR WMRVRRSSEC MKDDPITLFV ALSPQGTAQG
760 770 780 790 800
ELFLDDGHTF NYQTRQEFLL RRFSFSGNTL VSSSADPEGH FETPIWIERV
810 820 830 840 850
VIIGAGKPAA VVLQTKGSPE SRLSFQHDPE TSVLVLRKPG INVASDWSIH

LR
Length:852
Mass (Da):96,544
Last modified:April 5, 2011 - v1
Checksum:iD4E65914B91010E3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001458 Genomic DNA No translation available.
RefSeqiNP_001265121.1, NM_001278192.1
UniGeneiHs.595071

Genome annotation databases

EnsembliENST00000534779; ENSP00000435306; ENSG00000089597
GeneIDi23193
UCSCiuc010rma.4 human

Similar proteinsi

Entry informationi

Entry nameiE9PKU7_HUMAN
AccessioniPrimary (citable) accession number: E9PKU7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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