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Protein
Submitted name:

Tyrosine-protein kinase Lck

Gene

LCK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Tyrosine-protein kinase LckImported
Gene namesi
Name:LCKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:6524. LCK.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000182866.

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PKQ8.
PRIDEiE9PKQ8.

Expressioni

Gene expression databases

BgeeiENSG00000182866.
ExpressionAtlasiE9PKQ8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PKQ8.
SMRiE9PKQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini119 – 179SH3InterPro annotationAdd BLAST61

Keywords - Domaini

SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118938.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR000980. SH2.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00018. SH3_1. 1 hit.
PRINTSiPR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00326. SH3. 1 hit.
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiView protein in PROSITE
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Fragment.

E9PKQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGCGCSSHPE DDWMENIDVC ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT
60 70 80 90 100
YEGSNPPASP LQGDPRQQGL KDKACGSLAV GFHLSPTYFL PGLAFLVPHP
110 120 130 140 150
VTPGFLPIPA RFSLMPLVFT DNLVIALHSY EPSHDGDLGF EKGEQLRILE
160 170 180 190 200
QSGEWWKAQS LTTGQEGFIP FNFVAKANSL EPEPWFFKNL SRKDAERQLL
Length:200
Mass (Da):22,150
Last modified:April 5, 2011 - v1
Checksum:i5B49D43ED0540F9C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei200Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109945 Genomic DNA. No translation available.
AL121991 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000482949; ENSP00000431517; ENSG00000182866.
UCSCiuc057ejn.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE9PKQ8_HUMAN
AccessioniPrimary (citable) accession number: E9PKQ8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 7, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported