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E9PKM0

- E9PKM0_HUMAN

UniProt

E9PKM0 - E9PKM0_HUMAN

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Protein
Submitted name: Paired box protein Pax-6
Gene
PAX6
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. multicellular organismal development Source: UniProtKB-KW
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotationSAAS annotations

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotations

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Paired box protein Pax-6Imported
Gene namesi
Name:PAX6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:8620. PAX6.

Subcellular locationi

Nucleus By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiE9PKM0.
BgeeiE9PKM0.

Structurei

3D structure databases

ProteinModelPortaliE9PKM0.

Family & Domainsi

Sequence similaritiesi

Contains 1 paired domain.UniRule annotation
Contains paired domain.SAAS annotations

Keywords - Domaini

Paired boxUniRule annotationSAAS annotations

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00292. PAX. 1 hit.
[Graphical view]
PRINTSiPR00027. PAIREDBOX.
SMARTiSM00351. PAX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9PKM0-1 [UniParc]FASTAAdd to Basket

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MQNSHSGVNQ LGGVFVNGRP LPDSTRQKIV ELAHSGARPC DISRILQVSN   50
GCVSKIL 57
Length:57
Mass (Da):6,086
Last modified:May 14, 2014 - v2
Checksum:i27EE9F6D3D8F1790
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei57 – 571Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z83307 Genomic DNA. No translation available.
Z95332 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000524853; ENSP00000431585; ENSG00000007372.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z83307 Genomic DNA. No translation available.
Z95332 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E9PKM0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000524853 ; ENSP00000431585 ; ENSG00000007372 .

Organism-specific databases

HGNCi HGNC:8620. PAX6.
GenAtlasi Search...

Miscellaneous databases

NextBioi 35502951.

Gene expression databases

ArrayExpressi E9PKM0.
Bgeei E9PKM0.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00292. PAX. 1 hit.
[Graphical view ]
PRINTSi PR00027. PAIREDBOX.
SMARTi SM00351. PAX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE9PKM0_HUMAN
AccessioniPrimary (citable) accession number: E9PKM0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: May 14, 2014
Last modified: July 9, 2014
This is version 23 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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