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Protein
Submitted name:

Thioredoxin reductase 1, cytoplasmic

Gene

TXNRD1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Thioredoxin reductase 1, cytoplasmicImported
Gene namesi
Name:TXNRD1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000198431.15
HGNCiHGNC:12437 TXNRD1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198431

PTM / Processingi

Proteomic databases

MaxQBiE9PKI4
PeptideAtlasiE9PKI4
PRIDEiE9PKI4

Expressioni

Gene expression databases

BgeeiENSG00000198431
ExpressionAtlasiE9PKI4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PKI4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 71FAD/NAD-binding_domInterPro annotationAdd BLAST59

Phylogenomic databases

eggNOGiKOG1752 Eukaryota
KOG4716 Eukaryota
COG1249 LUCA
GeneTreeiENSGT00390000007578

Family and domain databases

Gene3Di3.50.50.601 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR023753 FAD/NAD-binding_dom
IPR012999 Pyr_OxRdtase_I_AS
PfamiView protein in Pfam
PF07992 Pyr_redox_2, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
PROSITEiView protein in PROSITE
PS00076 PYRIDINE_REDOX_1, 1 hit

Sequencei

Sequence statusi: Fragment.

E9PKI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGPEDLPKS YDYDLIIIGG GSGGLAAAKE AAQYGKKVMV LDFVTPTPLG
60 70
TRWGLGGTCV NVGCIPKKLM HQ
Length:72
Mass (Da):7,551
Last modified:April 5, 2011 - v1
Checksum:iDB46A60506714009
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei72Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC089983 Genomic DNA No translation available.
AC090107 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000531689; ENSP00000433507; ENSG00000198431
UCSCiuc058soc.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PKI4_HUMAN
AccessioniPrimary (citable) accession number: E9PKI4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported