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E9PKH0

- E9PKH0_HUMAN

UniProt

E9PKH0 - E9PKH0_HUMAN

Protein
Submitted name:

Receptor-type tyrosine-protein phosphatase C

Gene

PTPRC

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 2 (03 Apr 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: InterPro

    GO - Biological processi

    1. T cell receptor signaling pathway Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Receptor-type tyrosine-protein phosphatase CImported
    Gene namesi
    Name:PTPRCImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:9666. PTPRC.

    Expressioni

    Gene expression databases

    ArrayExpressiE9PKH0.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PKH0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    OrthoDBiEOG7XSTCW.

    Family and domain databases

    Gene3Di2.60.40.10. 2 hits.
    3.90.190.10. 1 hit.
    InterProiIPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    IPR016335. Leukocyte_common_ag.
    IPR029021. Prot-tyrosine_phosphatase-like.
    IPR024739. PTP_recept_N.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view]
    PfamiPF12567. CD45. 1 hit.
    PF00041. fn3. 2 hits.
    PF12453. PTP_N. 1 hit.
    PF00102. Y_phosphatase. 1 hit.
    [Graphical view]
    SMARTiSM00060. FN3. 2 hits.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 1 hit.
    SSF52799. SSF52799. 1 hit.
    PROSITEiPS50853. FN3. 2 hits.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    E9PKH0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTMYLWLKLL AFGFAFLDTE VFVTGQSPTP SPTGVSSVQT PHLPTHADSQ    50
    TPSAGTDTQT FSGSAANAKL NPTPGSNAIS DAYLNASETT TLSPSGSAVI 100
    STTTIATTPS KPTCDEKYAN ITVDYLYNKE TKLFTAKLNV NENVECGNNT 150
    CTNNEVHNLT ECKNASVSIS HNSCTAPDKT LILDVPPGVE KFQLHDCTQV 200
    EKADTTICLK WKNIETFTCD TQNITYRFQC GNMIFDNKEI KLENLEPEHE 250
    YKCDSEILYN NHKFTNASKI IKTDFGSPGE PQIIFCRSEA AHQGVITWNP 300
    PQRSFHNFTL CYIKETEKDC LNLDKNLIKY DLQNLKPYTK YVLSLHAYII 350
    AKVQRNGSAA MCHFTTKSAP PSQVWNMTVS MTSDNSMHVK CRPPRDRNGP 400
    HERYHLEVEA GNTLVRNESH KNCDFRVKDL QYSTDYTFKA YFHNGDYPGE 450
    PFILHHSTSY NSKALIAFLA FLIIVTSIAL LVVLYKIYDL HKKRSCNLDE 500
    QQELVERDDE KQLMNVEPIH ADILLETYKR KIADEGRLFL AEFQSIPRVF 550
    SKFPIKEARK PFNQNKNRYV DILPYDYNRV ELSEINGDAG SNYINASYID 600
    Length:600
    Mass (Da):67,888
    Last modified:April 3, 2013 - v2
    Checksum:iA0D6E743E843EFF1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei600 – 6001Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL157402 Genomic DNA. No translation available.
    AL355988 Genomic DNA. No translation available.
    KF510707 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000530727; ENSP00000433536; ENSG00000081237.
    UCSCiuc009wzf.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL157402 Genomic DNA. No translation available.
    AL355988 Genomic DNA. No translation available.
    KF510707 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9PKH0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000530727 ; ENSP00000433536 ; ENSG00000081237 .
    UCSCi uc009wzf.2. human.

    Organism-specific databases

    HGNCi HGNC:9666. PTPRC.
    GenAtlasi Search...

    Phylogenomic databases

    OrthoDBi EOG7XSTCW.

    Miscellaneous databases

    ChiTaRSi PTPRC. human.
    NextBioi 35502903.

    Gene expression databases

    ArrayExpressi E9PKH0.

    Family and domain databases

    Gene3Di 2.60.40.10. 2 hits.
    3.90.190.10. 1 hit.
    InterProi IPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    IPR016335. Leukocyte_common_ag.
    IPR029021. Prot-tyrosine_phosphatase-like.
    IPR024739. PTP_recept_N.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view ]
    Pfami PF12567. CD45. 1 hit.
    PF00041. fn3. 2 hits.
    PF12453. PTP_N. 1 hit.
    PF00102. Y_phosphatase. 1 hit.
    [Graphical view ]
    SMARTi SM00060. FN3. 2 hits.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 1 hit.
    SSF52799. SSF52799. 1 hit.
    PROSITEi PS50853. FN3. 2 hits.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PKH0_HUMAN
    AccessioniPrimary (citable) accession number: E9PKH0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 3, 2013
    Last modified: October 1, 2014
    This is version 30 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3