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E9PKC6

- E9PKC6_HUMAN

UniProt

E9PKC6 - E9PKC6_HUMAN

Protein
Submitted name:

CD44 antigen

Gene

CD44

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. hyaluronic acid binding Source: Ensembl

    GO - Biological processi

    1. branching involved in prostate gland morphogenesis Source: Ensembl
    2. branching involved in ureteric bud morphogenesis Source: Ensembl
    3. cell adhesion Source: Ensembl
    4. positive regulation of gene expression Source: Ensembl
    5. Wnt signaling pathway Source: Ensembl
    6. wound healing involved in inflammatory response Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CD44 antigenImported
    Gene namesi
    Name:CD44Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:1681. CD44.

    Subcellular locationi

    GO - Cellular componenti

    1. basolateral plasma membrane Source: Ensembl
    2. external side of plasma membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiE9PKC6.
    BgeeiE9PKC6.

    Structurei

    3D structure databases

    ProteinModelPortaliE9PKC6.
    SMRiE9PKC6. Positions 20-78.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.10.100.10. 1 hit.
    InterProiIPR016186. C-type_lectin-like.
    IPR016187. C-type_lectin_fold.
    IPR001231. CD44_antigen.
    IPR000538. Link.
    [Graphical view]
    PfamiPF00193. Xlink. 1 hit.
    [Graphical view]
    PRINTSiPR00658. CD44.
    SUPFAMiSSF56436. SSF56436. 1 hit.
    PROSITEiPS50963. LINK_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9PKC6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA   50
    DLCKAFNSTL PTMAQMEKAL SIGFETCR 78
    Length:78
    Mass (Da):8,812
    Last modified:April 5, 2011 - v1
    Checksum:i47F418A5EB56939D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL133330 Genomic DNA. No translation available.
    AL136989 Genomic DNA. No translation available.
    AL356215 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000526025; ENSP00000435377; ENSG00000026508.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL133330 Genomic DNA. No translation available.
    AL136989 Genomic DNA. No translation available.
    AL356215 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9PKC6.
    SMRi E9PKC6. Positions 20-78.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000526025 ; ENSP00000435377 ; ENSG00000026508 .

    Organism-specific databases

    HGNCi HGNC:1681. CD44.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi CD44. human.
    NextBioi 35502861.

    Gene expression databases

    ArrayExpressi E9PKC6.
    Bgeei E9PKC6.

    Family and domain databases

    Gene3Di 3.10.100.10. 1 hit.
    InterProi IPR016186. C-type_lectin-like.
    IPR016187. C-type_lectin_fold.
    IPR001231. CD44_antigen.
    IPR000538. Link.
    [Graphical view ]
    Pfami PF00193. Xlink. 1 hit.
    [Graphical view ]
    PRINTSi PR00658. CD44.
    SUPFAMi SSF56436. SSF56436. 1 hit.
    PROSITEi PS50963. LINK_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    5. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE9PKC6_HUMAN
    AccessioniPrimary (citable) accession number: E9PKC6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3