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Protein
Submitted name:

CD44 antigen

Gene

CD44

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CD44 antigenImported
Gene namesi
Name:CD44Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:1681. CD44.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000026508.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500324510721 – 78Sequence analysisAdd BLAST58

Proteomic databases

MaxQBiE9PKC6.
PaxDbiE9PKC6.
PeptideAtlasiE9PKC6.
PRIDEiE9PKC6.

Expressioni

Gene expression databases

BgeeiENSG00000026508.
ExpressionAtlasiE9PKC6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000398632.

Structurei

3D structure databases

ProteinModelPortaliE9PKC6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 78LinkInterPro annotationAdd BLAST47

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
GeneTreeiENSGT00530000063822.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like/link.
IPR001231. CD44_antigen.
IPR016187. CTDL_fold.
IPR000538. Link_dom.
[Graphical view]
PfamiPF00193. Xlink. 1 hit.
[Graphical view]
PRINTSiPR00658. CD44.
SMARTiSM00445. LINK. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS50963. LINK_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9PKC6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA
60 70
DLCKAFNSTL PTMAQMEKAL SIGFETCR
Length:78
Mass (Da):8,812
Last modified:April 5, 2011 - v1
Checksum:i47F418A5EB56939D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133330 Genomic DNA. No translation available.
AL136989 Genomic DNA. No translation available.
AL356215 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000526025; ENSP00000435377; ENSG00000026508.
UCSCiuc058aik.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133330 Genomic DNA. No translation available.
AL136989 Genomic DNA. No translation available.
AL356215 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PKC6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000398632.

Proteomic databases

MaxQBiE9PKC6.
PaxDbiE9PKC6.
PeptideAtlasiE9PKC6.
PRIDEiE9PKC6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000526025; ENSP00000435377; ENSG00000026508.
UCSCiuc058aik.1. human.

Organism-specific databases

HGNCiHGNC:1681. CD44.
OpenTargetsiENSG00000026508.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
GeneTreeiENSGT00530000063822.

Miscellaneous databases

ChiTaRSiCD44. human.

Gene expression databases

BgeeiENSG00000026508.
ExpressionAtlasiE9PKC6. baseline and differential.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like/link.
IPR001231. CD44_antigen.
IPR016187. CTDL_fold.
IPR000538. Link_dom.
[Graphical view]
PfamiPF00193. Xlink. 1 hit.
[Graphical view]
PRINTSiPR00658. CD44.
SMARTiSM00445. LINK. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS50963. LINK_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9PKC6_HUMAN
AccessioniPrimary (citable) accession number: E9PKC6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 30, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.