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Protein
Submitted name:

CD44 antigen

Gene

CD44

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD44 antigenImported
Gene namesi
Name:CD44Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:1681. CD44.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000026508.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500324510721 – 78Sequence analysisAdd BLAST58

Proteomic databases

MaxQBiE9PKC6.
PaxDbiE9PKC6.
PeptideAtlasiE9PKC6.
PRIDEiE9PKC6.

Expressioni

Gene expression databases

BgeeiENSG00000026508.
ExpressionAtlasiE9PKC6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000398632.

Structurei

3D structure databases

ProteinModelPortaliE9PKC6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 78LinkInterPro annotationAdd BLAST47

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
GeneTreeiENSGT00530000063822.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR016186. C-type_lectin-like/link.
IPR001231. CD44_antigen.
IPR016187. CTDL_fold.
IPR000538. Link_dom.
PANTHERiPTHR10225:SF8. PTHR10225:SF8. 1 hit.
PfamiView protein in Pfam
PF00193. Xlink. 1 hit.
PRINTSiPR00658. CD44.
SMARTiView protein in SMART
SM00445. LINK. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS50963. LINK_2. 1 hit.

Sequencei

Sequence statusi: Complete.

E9PKC6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA
60 70
DLCKAFNSTL PTMAQMEKAL SIGFETCR
Length:78
Mass (Da):8,812
Last modified:April 5, 2011 - v1
Checksum:i47F418A5EB56939D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133330 Genomic DNA. No translation available.
AL136989 Genomic DNA. No translation available.
AL356215 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000526025; ENSP00000435377; ENSG00000026508.
UCSCiuc058aik.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133330 Genomic DNA. No translation available.
AL136989 Genomic DNA. No translation available.
AL356215 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PKC6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000398632.

Proteomic databases

MaxQBiE9PKC6.
PaxDbiE9PKC6.
PeptideAtlasiE9PKC6.
PRIDEiE9PKC6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000526025; ENSP00000435377; ENSG00000026508.
UCSCiuc058aik.1. human.

Organism-specific databases

HGNCiHGNC:1681. CD44.
OpenTargetsiENSG00000026508.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IZCP. Eukaryota.
ENOG4111S6T. LUCA.
GeneTreeiENSGT00530000063822.

Miscellaneous databases

ChiTaRSiCD44. human.

Gene expression databases

BgeeiENSG00000026508.
ExpressionAtlasiE9PKC6. baseline and differential.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR016186. C-type_lectin-like/link.
IPR001231. CD44_antigen.
IPR016187. CTDL_fold.
IPR000538. Link_dom.
PANTHERiPTHR10225:SF8. PTHR10225:SF8. 1 hit.
PfamiView protein in Pfam
PF00193. Xlink. 1 hit.
PRINTSiPR00658. CD44.
SMARTiView protein in SMART
SM00445. LINK. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS50963. LINK_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE9PKC6_HUMAN
AccessioniPrimary (citable) accession number: E9PKC6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 10, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.