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Protein
Submitted name:

Pleckstrin homology domain-containing family A member 7

Gene

PLEKHA7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Pleckstrin homology domain-containing family A member 7Imported
Gene namesi
Name:PLEKHA7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:27049. PLEKHA7.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166689.

PTM / Processingi

Proteomic databases

MaxQBiE9PKC0.
PaxDbiE9PKC0.
PeptideAtlasiE9PKC0.
PRIDEiE9PKC0.

PTM databases

iPTMnetiE9PKC0.

Expressioni

Gene expression databases

BgeeiENSG00000166689.
ExpressionAtlasiE9PKC0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9PKC0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 42WWInterPro annotationAdd BLAST34
Domaini54 – 87WWInterPro annotationAdd BLAST34
Domaini164 – 282PHInterPro annotationAdd BLAST119

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili705 – 739Sequence analysisAdd BLAST35
Coiled coili771 – 798Sequence analysisAdd BLAST28
Coiled coili1070 – 1093Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410INUD. Eukaryota.
ENOG4111YSB. LUCA.
GeneTreeiENSGT00530000063012.
OMAiLDLKMTG.
OrthoDBiEOG091G00N4.
PhylomeDBiE9PKC0.

Family and domain databases

CDDicd00201. WW. 1 hit.
Gene3Di2.30.29.30. 1 hit.
InterProiView protein in InterPro
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR001202. WW_dom.
PfamiView protein in Pfam
PF00169. PH. 1 hit.
SMARTiView protein in SMART
SM00233. PH. 1 hit.
SM00456. WW. 2 hits.
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF51045. SSF51045. 2 hits.
PROSITEiView protein in PROSITE
PS50003. PH_DOMAIN. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 2 hits.

Sequencei

Sequence statusi: Complete.

E9PKC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAATVGRDT LPEHWSYGVC RDGRVFFIND QLRCTTWLHP RTGEPVNSGH
60 70 80 90 100
MIRSDLPRGW EEGFTEEGAS YFIDHNQQTT AFRHPVTGQF SPENSEFILQ
110 120 130 140 150
EEPNPHMSKQ DRNQRPSSMV SETSTAGTAS TLEAKPGPKI IKSSSKVHSF
160 170 180 190 200
GKRDQAIRRN PNVPVVVRGW LHKQDSSGMR LWKRRWFVLA DYCLFYYKDS
210 220 230 240 250
REEAVLGSIP LPSYVISPVA PEDRISRKYS FKAVHTGMRA LIYNSSTAGS
260 270 280 290 300
QAEQSGMRTY YFSADTQEDM NAWVRAMNQA AQVLSRSSLK RDMEKVERQA
310 320 330 340 350
VPQANHTESC HECGRVGPGH TRDCPHRGHD DIVNFERQEQ EGEQYRSQRD
360 370 380 390 400
PLEGKRDRSK ARSPYSPAEE DALFMDLPTG PRGQQAQPQR AEKNGMLPAS
410 420 430 440 450
YGPGEQNGTG GYQRAFPPRT NPEKHSQRKS NLAQVEHWAR AQKGDSRSLP
460 470 480 490 500
LDQTLPRQGP GQSLSFPENY QTLPKSTRHP SGGSSPPPRN LPSDYKYAQD
510 520 530 540 550
RASHLKMSSE ERRAHRDGTV WQLYEWQQRQ QFRHGSPTAP ICLGSPEFTD
560 570 580 590 600
QGRSRSMLEV PRSISVPPSP SDIPPPGPPR VFPPRRPHTP AERVTVKPPD
610 620 630 640 650
QRRSVDISLG DSPRRARGHA VKNSSHVDRR SMPSMGYMTH TVSAPSLHGK
660 670 680 690 700
SADDTYLQLK KDLEYLDLKM TGRDLLKDRS LKPVKIAESD TDVKLSIFCE
710 720 730 740 750
QDRVLQDLED KIRALKENKD QLESVLEVLH RQMEQYRDQP QHLEKIAYQQ
760 770 780 790 800
KLLQEDLVHI RAELSRESTE MENAWNEYLK LENDVEQLKQ TLQEQHRRAF
810 820 830 840 850
FFQEKSQIQK DLWRIEDVTA GLSANKENFR ILVESVKNPE RKTVPLFPHP
860 870 880 890 900
PVPSLSTSES KPPPQPSPPT SPVRTPLEVR LFPQLQTYVP YRPHPPQLRK
910 920 930 940 950
VTSPLQSPTK AKPKVEDEAP PRPPLPELYS PEDQPPAVPP LPREATIIRH
960 970 980 990 1000
TSVRGLKRQS DERKRDRELG QCVNGDSRVE LRSYVSEPEL ATLSGDMAQP
1010 1020 1030 1040 1050
SLGLVGPESR YQTLPGRGLS GSTSRLQQSS TIAPYVTLRR GLNAESSKAT
1060 1070 1080 1090 1100
FPRPKSALER LYSGDHQRGK MSAEEQLERM KRHQKALVRE RKRTLGQGER
1110 1120 1130 1140 1150
TGLPSSRYLS RPLPGDLGSW KREQDFDLQL LERVVQGEKK DKEENGWLKV
1160 1170 1180 1190 1200
QAMPVTELDL EPQDYDLDIS RELSKPEKVS IPERYVELDP EEPPSLEELQ
1210 1220 1230 1240 1250
ARYRKAEKIR NILARSSMCN LQPTSGQDQN SVADLDLQLQ EQERIINISY
1260 1270
ALASEASQRS KQVAAQAVTD P
Length:1,271
Mass (Da):144,424
Last modified:April 5, 2011 - v1
Checksum:i310BE965442CC769
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026639 Genomic DNA. No translation available.
AC116533 Genomic DNA. No translation available.
AC127033 Genomic DNA. No translation available.
AC131064 Genomic DNA. No translation available.
RefSeqiNP_001316559.1. NM_001329630.1.
UniGeneiHs.12332.
Hs.729280.
Hs.733020.

Genome annotation databases

EnsembliENST00000531066; ENSP00000435389; ENSG00000166689.
GeneIDi144100.
UCSCiuc057zkp.1. human.

Similar proteinsi

Entry informationi

Entry nameiE9PKC0_HUMAN
AccessioniPrimary (citable) accession number: E9PKC0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: August 30, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported