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Protein
Submitted name:

Thioredoxin reductase 1, cytoplasmic

Gene

TXNRD1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Thioredoxin reductase 1, cytoplasmicImported
Gene namesi
Name:TXNRD1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:12437. TXNRD1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198431.

PTM / Processingi

Proteomic databases

MaxQBiE9PJU2.
PaxDbiE9PJU2.
PeptideAtlasiE9PJU2.

Expressioni

Gene expression databases

BgeeiENSG00000198431.
ExpressionAtlasiE9PJU2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000434516.

Structurei

3D structure databases

ProteinModelPortaliE9PJU2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1752. Eukaryota.
KOG4716. Eukaryota.
COG1249. LUCA.
GeneTreeiENSGT00390000007578.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.

Sequencei

Sequence statusi: Fragment.

E9PJU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAMLPTGSH SAVLPPSHCS TAPPSTSQEP SSSADPKLCL SPPTSDSRQE
60 70 80 90
RNVQFGLAYQ EGRLQKLLKM NGPEDLPKSY DYDLIIIGGG SGGLAA
Length:96
Mass (Da):10,053
Last modified:April 5, 2011 - v1
Checksum:i2AA13DF515387D1C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei96Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC089983 Genomic DNA. No translation available.
AC090107 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000528079; ENSP00000433732; ENSG00000198431.
UCSCiuc058sof.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC089983 Genomic DNA. No translation available.
AC090107 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9PJU2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000434516.

Proteomic databases

MaxQBiE9PJU2.
PaxDbiE9PJU2.
PeptideAtlasiE9PJU2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000528079; ENSP00000433732; ENSG00000198431.
UCSCiuc058sof.1. human.

Organism-specific databases

HGNCiHGNC:12437. TXNRD1.
OpenTargetsiENSG00000198431.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1752. Eukaryota.
KOG4716. Eukaryota.
COG1249. LUCA.
GeneTreeiENSGT00390000007578.

Miscellaneous databases

ChiTaRSiTXNRD1. human.

Gene expression databases

BgeeiENSG00000198431.
ExpressionAtlasiE9PJU2. baseline and differential.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE9PJU2_HUMAN
AccessioniPrimary (citable) accession number: E9PJU2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 30, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.